Results 41 to 50 of about 2,474 (180)

Conditional Knockout of Raptor/mTORC1 Results in Dentin Malformation

Frontiers in Physiology, 2019
mTORC1 signaling plays an important role in extracellular and intracellular signals, including growth factors, nutrients, energy metabolism, and stress. However, the functional role of mTORC1 in dentinogenesis is unknown.
Furong Xie, Furong Xie, Furong Xie, Qinggang Dai, Qinggang Dai, Qinggang Dai, Xiao Liu, Xiao Liu, Xiao Liu, Jun Wang, Jun Wang, Jun Wang   +11 more
doaj   +1 more source

Unravelling the Genetic Basis of Dentinogenesis Imperfecta

International Dental Journal, 2023
Aim or Purpose: Dentinogenesis imperfecta (DI) is an autosomal dominant genetic disorder affecting dentine formation. This study aimed to perform mutational analysis in individuals with DI to unravel its molecular mechanisms.
Dr Maleeha Gilani, Associate Professor Robert Anthonappa   +1 more
doaj   +1 more source

Advances in 3D Printing for Removable Prosthetics—Insights and Perspectives

Journal of Esthetic and Restorative Dentistry, EarlyView.
ABSTRACT Objective This review summarizes recent advances in three‐dimensional (3D) printing for removable prosthodontics, including complete dentures, removable partial dentures, implant‐retained overdentures, and occlusal splints. The aim is to provide clinicians with an overview of current technologies, clinical performance, and future perspectives.
O. Schubert, D. Edelhoff, J. F. Güth, J. Schweiger   +3 more
wiley   +1 more source

Reduced Dietary Protein Induces Changes in the Dental Proteome

Journal of Experimental Zoology Part B: Molecular and Developmental Evolution, Volume 346, Issue 2, Page 107-127, March 2026.
Low dietary protein (10%) from normal (20%) does change protein expression in tooth proteome and alter developmental pathways. Among the significant protein expressions changes are actin‐based myosins, tooth, and bone development proteins. Perplexingly tooth size is not altered, suggesting more nuanced phenotypic response to low dietary protein in ...
Robert W. Burroughs, Christopher J. Percival, Natasha S. Vitek   +2 more
wiley   +1 more source

CLINICAL CASE OF RARE TYPE V OSTEOGENESIS IMPERFECTA

Педиатрическая фармакология, 2015
Osteogenesis imperfecta, also known as the brittle bone disease, is a clinically heterogenic hereditary connective tissue disease characterized by brittle bones and high risk of skeletal bone fractures.
G. T. Yakhyayeva, T. V. Margieva, L. S. Namazova-Baranova, K. V. Savostyanov, A. A. Pushkov, N. V. Zhurkova, K. V. Zherdev, N. D. Vashakmadze, A. K. Gevorkyan   +8 more
doaj   +1 more source

Co‐Occurrence of Osteogenesis Imperfecta Type III and Chronic Abruption‐Oligohydramnios Sequence: A Case Report Suggesting a Possible Role of Type I Collagen Fragility

Journal of Obstetrics and Gynaecology Research, Volume 52, Issue 2, February 2026.
ABSTRACT Pregnancy complicated by severe osteogenesis imperfecta (OI) is rare, and chronic abruption‐oligohydramnios sequence (CAOS) is an uncommon obstetric disorder characterized by persistent bleeding and oligohydramnios without membrane rupture. To our knowledge, this is the first report describing the coexistence of type III OI and CAOS. A 24‐year‐
Ayumi Okuyama, Tatsuya Izdebski, Minako Goto, Kohei Seo, Makiko Tominaga, Kiyotake Ichizuka   +5 more
wiley   +1 more source

Prevalence, Characteristics, and Predictive Factors of Dentoalveolar and Spreading Odontogenic Infections in Children Treated Under General Anaesthesia

International Journal of Paediatric Dentistry, Volume 36, Issue 1, Page 13-18, January 2026.
ABSTRACT Background Children receiving dental treatment under general anesthesia (GA) often have odontogenic infections (OIs). Early detection and treatment of patients at risk of OIs can improve oral health and prevent early tooth extractions. Aim To investigate the prevalence, characteristics, and predictive factors of OIs in children receiving ...
Annmari Hyppänen, Fanny Mussalo, Johanna Snäll, Heikki Alapulli, Eija Salmela   +4 more
wiley   +1 more source

Epidemiological and Clinical Features of Regional Odontodysplasia in South Korean Pediatric Patients: A Multicenter Case Series Study

International Journal of Paediatric Dentistry, Volume 36, Issue 1, Page 140-152, January 2026.
ABSTRACT Background Regional odontodysplasia (RO) is a rare developmental dental anomaly with unknown prevalence. Current knowledge is largely limited to individual case reports. Aim This study aims to present epidemiological data, clinical features, and radiographic characteristics of pediatric and adolescent patients with RO in South Korea. Design In
So Dam Lee, Je Seon Song, Hyo Seoul Lee, Hyuntae Kim, Yeonmi Yang, Ko Eun Lee   +5 more
wiley   +1 more source

Expanding the Clinical Spectrum of Bruck Syndrome: A Case Report and Literature Review

Case Reports in Pediatrics, Volume 2026, Issue 1, 2026.
Background Bruck syndrome is a rare autosomal recessive disorder characterized by osteogenesis imperfecta–like bone fragility and congenital joint contractures. Clinical overlap with other connective tissue disorders makes early diagnosis challenging, and genetic testing remains essential.
Ansam Nafah, May Shihab, Reem Shihab, Lana M. Dweekat, Hala O. Abdallah, Andrea Scaramuzza   +5 more
wiley   +1 more source

Genetic Aspects of Dentinogenesis Imperfecta

Journal of Dentistry Indonesia, 2015
Dentinogenesis Imperfecta (DI) is a hereditary, simple autosomal dominant disorder showing abnormalities in the dentin of the developing teeth and occurring at a rate of about 1 in 8000 births.
Elza Ibrahim Auerkari, Hedijanti Joenoes
doaj   +1 more source