Results 121 to 130 of about 29,720,759 (240)
An on‐resin dual‐modification strategy for peptides is presented, comprising S‐alkynylation of peptide thiosulfonates and regioselective iridium‐catalyzed azide–thioalkyne cycloaddition. This method reliably provides access to peptides with intricate non‐canonical modifications, being compatible with complex peptides, alkynes and azides.
Marius Werner +5 more
wiley +1 more source
Reciprocal control of viral infection and phosphoinositide dynamics
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley +1 more source
I.C: Infectious clonea: The European Nucleotide ArchiveStrains of DENV-1 used.
William B Lott (826053) +6 more
core +1 more source
Host‐specific compatibility between RNF138‐like proteins and flavivirus NS5 determines NS5 stability. Mammalian RNF138 but not arthropod homologs recognizes and induces conserved NS5/RdRp K48‐linked ubiquitination and proteasomal degradation, thereby restricting viral replication. Ectopic RNF138 in mice attenuates TBEV‐induced pathogenesis. (Created in
Jialiang Sun +6 more
wiley +1 more source
Structural similarities between Zika (ZIKV) and dengue virus (DENV) leads to the induction of cross-reactive responses. We have previously demonstrated that ZIKV exposed macaques significantly enhance DENV viremia.
William G. Valiant +5 more
doaj +1 more source
Upon JEV infection, ZNF33B recruits METTL14 to stabilize the METTL3‐METTL14 m6A methyltransferase complex, leading to increased m6A modification of host transcripts, including Trim25 mRNA. ZNF33B selectively binds m6A‐modified sites on Trim25 mRNA and accelerates its decay, resulting in reduced TRIM25 protein abundance.
Jian Du +9 more
wiley +1 more source
Plaque mean area of DENV-1 isolates.
Plaque mean area of DENV-1 isolates.
Alicia S. Mistchenko (649200) +2 more
core +1 more source
ABSTRACT Background and Aims Dengue, a mosquito‐borne viral infection, poses a significant public health challenge in Bangladesh, with a recent surge in reported dengue cases and fatalities at the national level. This paper aims to investigate the association between climatic factors and the 2023 dengue outbreak in Bangladesh, with a particular focus ...
Mohammad Ashraful Amin +3 more
wiley +1 more source
(A) The DENV-1 tree was constructed using the whole nucleotide envelope protein gene sequences from DENV-1 and shows the relationships of 50 strains from different sources including 10 DENV-1 strains isolated in China. (B) The DENV-2 tree was constructed
Hong Deng (115865) +12 more
core +1 more source
Genomic Characterization of Circulating Dengue Virus, Ethiopia, 2022–2023
In Ethiopia, dengue virus (DENV) infections have been reported in several regions; however, little is known about the genetic diversity of circulating viruses.
Adugna Abera +24 more
doaj +1 more source

