Results 141 to 150 of about 29,720,759 (240)

Functional properties of DENV EDIII-reactive antibodies in human DENV-1-infected sera and rabbit antiserum to EDIII

Molecular Medicine Reports, 2016
The envelope domain III (EDIII) of the dengue virus (DENV) has been confirmed to be involved in receptor binding. It is the target of specific neutralizing antibodies, and is considered to be a promising subunit dengue vaccine candidate. However, several recent studies have shown that anti‑EDIII antibodies contribute little to the neutralizing or ...
Jing, Chen, Kun, Wen, Xiao-Quan, Li, Hai-Su, Yi, Xi-Xia, Ding, Yan-Fen, Huang, Yu-Xian, Pan, Dong-Mei, Hu, Biao, Di, Xiao-Yan, Che, Ning, Fu   +10 more
openaire   +3 more sources

Circulation of Dengue Virus Serotypes in the City of Makkah, Saudi Arabia, as Determined by Reverse Transcription Polymerase Chain Reaction

Canadian Journal of Infectious Diseases and Medical Microbiology, 2017
The present study was aimed to investigate the circulation of four dengue virus (DENV) serotypes in Makkah, Western Saudi Arabia. Blood samples were collected from 25 dengue fever-suspected patients and were subjected to molecular typing for DENV-1, DENV-
Sameer R. Organji, Hussein H. Abulreesh, Gamal E. H. Osman   +2 more
doaj   +1 more source

Primary vaccination with low dose live dengue 1 virus generates a proinflammatory, multifunctional T cell response in humans.

PLoS Neglected Tropical Diseases, 2012
The four dengue virus serotypes (DENV-1-DENV-4) have a large impact on global health, causing 50-100 million cases of dengue fever annually. Herein, we describe the first kinetic T cell response to a low-dose DENV-1 vaccination study (10 PFU) in humans ...
Janet C Lindow, Nathan Borochoff-Porte, Anna P Durbin, Stephen S Whitehead, Kelly A Fimlaid, Janice Y Bunn, Beth D Kirkpatrick   +6 more
doaj   +1 more source

Design and Synthesis of a Potent, Cell Active Purine‐Based Amidoxime Against the Dengue Virus

ChemistrySelect, Volume 11, Issue 36, 22 September 2026.
Scaffold hopping from our previous indolazepinone hit exemplifies purine SP‐835G with DENV2 EC50 0.1 µM, CC50>100 µM, clogP 3.61. Docking studies support its amidine metabolite operates as an allosteric inhibitor of DENV(pro). A flexible ether linker appears pivotal for enhancing binding and activity.
Dimitrios Kiousis, Despoina Giannioti, Georgia Kalyva, Vasiliki Zogali, Maharah Binte Abdul Mahid, Kitti Wing Ki Chan, Minos‐Timotheos Matsoukas, Subhash G. Vasudevan, Gerasimos Rassias   +8 more
wiley   +1 more source

Molecular and Serological Screening of West Nile and Usutu Virus in Birds and Humans: A Sentinel Study in Finland

Veterinary Medicine and Science, Volume 12, Issue 5, September 2026.
We developed sensitive real‐time PCR assays for West Nile virus and Usutu virus to screen bird and human samples in Finland. Although no positive samples were detected, active migratory flyways and recent cases in neighbouring countries highlight the risk of future introduction and the need for continued surveillance.
Ruut Joensuu, Maija T. Suvanto, Sanna Sainmaa, Viktor Olander, Roope Nykänen, Essi M. Korhonen, Anne J. Jääskeläinen   +6 more
wiley   +1 more source

Regional DENV serotype distribution.

, 2013
Regional data extracted from source documents for distribution of DENV-1, 2 and 3 serotypes. DENV-4 was not present in Brazil until 2011.DENV, dengue viruses.
João Bosco Siqueira, Jr (499712), Maria Glória Teixeira (248091), Germano L. C. Ferreira (499713), Lucia Bricks (499714), Graham Joint (499715)   +4 more
core   +1 more source

Potent Neutralization Ability of a Human Monoclonal Antibody Against Serotype 1 Dengue Virus

Frontiers in Microbiology, 2018
The incidence of dengue virus (DENV) infections has been escalating in tropical and subtropical countries, but there are still no effective therapeutic options.
Jiansheng Lu, Rong Wang, Binghui Xia, Yunzhou Yu, Xiaowei Zhou, Zhixin Yang, Peitang Huang   +6 more
doaj   +1 more source

Climate Informed Dengue Prediction and Future Risk Under a Changing Monsoon Climate in Kerala, India

GeoHealth, Volume 10, Issue 9, September 2026.
Abstract Dengue fever has emerged as a major public health threat in India, with its burden projected to rise under climate change. This study investigates the influence of climate variability on dengue incidence in Kerala, a dengue hotspot in southern India, using 14 years of climate and dengue data (2006–2019).
Yacob Sophia, Mathew Koll Roxy, Surendranath Bindu Vaisakh, Pallipurathu Raghunathan Nair Sreelakshmi, Thekkumkara Surendran Anish, Pillaveetil Sathyadas Indu   +5 more
wiley   +1 more source

Cranberry Pomace Valorization: Composition, Extraction, Bioactivity, and Food Applications

Comprehensive Reviews in Food Science and Food Safety, Volume 25, Issue 5, September 2026.
ABSTRACT Cranberry pomace, the principal solid residue generated during cranberry processing, is increasingly recognized as a compositionally valuable coproduct rather than a waste material. This is particularly relevant in North America, where cranberry production is concentrated in the United States and Canada, the two leading producing countries ...
Ali Ali Redha, Tuba Esatbeyoglu
wiley   +1 more source

Phylogenetic studies reveal existence of multiple lineages of a single genotype of DENV-1 (genotype III) in India during 1956–2007 [PDF]

, 2009
Background Dengue virus type 1 (DENV-1) have been mostly circulating silently with dominant serotypes DENV-2 and DENV-3 in India. However recent times have marked an increase in DENV-1 circulation in yearly outbreaks.
Lal Shiv, Chhabra Mala, RS Rautela, Arvind Rai, PV Lakshmana Rao, Kukreti Himani, Rao PV Lakshmana, Saxena Parag, Mittal Veena, D Bhattacharya, Manmohan Parida, Parida Manmohan, Bhattacharya D, Parag Saxena, Veena Mittal, Mala Chhabra, Himani Kukreti, Shiv Lal, Rautela RS, Chaudhary Artee, Paban Dash, Artee Chaudhary, Dash Paban, Rai Arvind   +23 more
core   +1 more source