Results 151 to 160 of about 29,720,759 (240)

Early Warning Systems and Emergency Declarations During Brazil's Largest Dengue Outbreak

Tropical Medicine &International Health, Volume 31, Issue 9, Page 1183-1193, September 2026.
ABSTRACT Objectives Early warning systems (EWSs) are essential for alert, detection, and response to potential public health emergencies. Brazil's 2024 dengue epidemic, the largest ever recorded, offers a critical case for assessing correspondence between timely epidemic risk detection and health governance responsiveness.
Lorena Guadalupe Barberia, Alexandra Crispim Boing, Natália de Paula Moreira, Murilo Motta, Guilherme Pereira Ferreira, Dara Aparecida Vilela Pinto, Luiz Antonio Couto Soares, João de Oliveira Gusmão, Ana Paula Magalhães Brito, Sabrina Almeida, Tatiane C. Moraes de Sousa   +10 more
wiley   +1 more source

Population dynamics of DENV-1, DENV-2 and DENV-3 circulating lineages in Brazil.

, 2014
Panel A shows the proportion of federal states (total of 27) where each DENV serotype was molecularly confirmed from 2002 to 2012. Panels B, C and D depict changes in effective population size (Ne) over time (dashed lines) respectively for DENV-1, DENV-2
Nuno Rodrigues Faria (554050), Daniele B. A. Medeiros (554055), Sueli G. Rodrigues (554053), Jamilla A. Pantoja (554052), Valéria L. Carvalho (554054), Nazir Savji (200329), W. Ian Lipkin (67196), Marcio R. T. Nunes (5658712), Guy Baele (525074), Gustavo Palacios (67191), Pedro F. C. Vasconcelos (248082), Philippe Lemey (30422), Edivaldo Costa Sousa Jr (554051), Marc A. Suchard (36176)   +13 more
core   +1 more source

An international study on emerging arboviral infections and blood safety

Transfusion, Volume 66, Issue 9, Page 1786-1799, September 2026.
Abstract Background Emerging and re‐emerging arboviral infections are a risk to blood safety. We conducted an international survey on how blood establishments respond to current and future arbovirus threats. Study Design and Methods A questionnaire on arbovirus donor deferral strategies, pathogen reduction, and donation screening was distributed to ...
Piya Rajendra, Helen M. Faddy, Daniel Candotti, Carolina B. Bub, Jose M. Kutner, Steven J. Drews, Carmen L. Charlton, Sheila F. O'Brien, Wai‐Chiu Tsoi, Michel‐Andres Garcia‐Otalora, Claire Reynolds, Tuulia Palukka, Riikka Lehtisalo, Ruth Offergeld, Axel Seltsam, Marijke Weber‐Schehl, Nahid Chenarsabz, Naoko Goto, Sung‐Chan Park, So‐Yong Kwon, Ryanne Lieshout‐Krikke, Aneta Kopacz, Ewa Sulkowska, Oana‐Alexandra Șerban, Simona Ruta, Eugene Zhiburt, Maha Badawi, Josephine Mitchel, Ute Jentsch, Ángel Luis Pajares Herraiz, Ana Lafuente Guijosa, Gülşen Özkaya Şahin, Christoph Niederhauser, Marion C. Lanteri, Brian Custer, Galen Conti, Anthea Cheng, Shannah Secret, Peter Simmonds, Heli Harvala, on behalf of the Virology subgroup of the ISBT WP‐TTID   +40 more
wiley   +1 more source

Ligand‑Based Virtual Screening Discovery of Thienopyrimidinone Derivatives as Allosteric nSMase2 Modulators and Antivirals Against West Nile Virus

ChemMedChem, Volume 21, Issue 16, 27 August 2026.
Ligand‐based virtual screening of over five million compounds identifies a thienopyrimidinone hit as a novel allosteric nSMase2 modulator. Structure‐guided optimisation improves inhibitory potency and delivers derivatives with antiviral activity against West Nile virus, expanding the chemical space of nSMase2 inhibitors and supporting host‐directed ...
Hadrián Álvarez‐Fernández, Patricia Mingo‐Casas, Ana‐Belén Blázquez, Flavia Caridi, Miguel A. Martín‐Acebes, María‐Jesús Pérez‐Pérez, Eva‐María Priego   +6 more
wiley   +1 more source

Cross-reactive binding response of anti-peptide antibody against the sE recombinant protein of DENV-1, DENV-2 and DENV-3.

, 2016
Sera raised against each peptide group were pooled (n = 5) and the resulting immune sera were used to test the cross-reactive antibody response in ELISA.
Chit Laa Poh (167240), Kristin Kirk (2805601), William John Hannan McBride (720952), Lara Grollo (490606), Babu Ramanathan (2805598), John Aaskov (222730)   +5 more
core   +1 more source

Spatial and temporal distribution of confirmed cases of DENV-1 and DENV-4 infections between January and December 2009.

, 2013
Spatial and temporal distribution of confirmed cases of DENV-1 and DENV-4 infections between January and December 2009.
Claudine Roche (261221), Stéphane Lastere (5652655), Henri-Pierre Mallet (336530), Anita Teissier (336528), Van-Mai Cao-Lormeau (261219), Maite Aubry (336527), Elise Daudens (336529), John Aaskov (222730), Didier Musso (336531)   +8 more
core   +1 more source

Limited cross-reactivity of mouse monoclonal antibodies against Dengue virus capsid protein among four serotypes

Biologics: Targets & Therapy, 2012
Megumi Noda,1 Promsin Masrinoul,1 Chaweewan Punkum,1 Chonlatip Pipattanaboon,2,3 Pongrama Ramasoota,2,4 Chayanee Setthapramote,2,3 Tadahiro Sasaki,6 Mikiko Sasayama,1 Akifumi Yamashita,1,5 Takeshi Kurosu,6 Kazuyoshi Ikuta,6 Tamaki Okabayashi11Mahidol ...
Noda M, Masrinoul P, Punkum C, Pipattanaboon C, Ramasoota P, Setthapramote C, Sasaki T, Sasayama M, Yamashita A, Kurosu T, Ikuta K, Okabayashi T   +11 more
doaj  

DENV-1 and DENV-2 neutralizing antibody prevalence by year and birth cohort.

, 2016
Samples were collected from longitudinal cohort studies conducted in Iquitos between 1993 and 2010. Panel A: DENV-1 neutralizing antibody prevalence by year, based on birth cohorts. Panel B: DENV-2 neutralizing antibody prevalence by year, based on birth
Angelica Espinoza (2137915), Tadeusz J. Kochel (137222), Kanya C. Long (2137906), Wilma Casanova (2137918), Stalin Vilcarromero (372094), Eric S. Halsey (129244), Brett M. Forshey (249475), Sandra Olkowski (2137909), Steven T. Stoddard (167457), Thomas W. Scott (102260), Robert C. Reiner (2137912), Amy C. Morrison (108730), Helen J. Wearing (245189)   +12 more
core   +1 more source

Identification of an Arylnaphthalene Lignan Derivative as an Inhibitor against Dengue Virus Serotypes 1 to 4 (DENV-1 to -4) Using a Newly Developed DENV-3 Infectious Clone and Replicon. [PDF]

Microbiol Spectr, 2023
Hu M, Li WF, Wu T, Yang Y, Chen G, Chen T, Liu Y, Mei Y, Wu, Wei Y, Luo T, Zhang HJ, Li YP.   +12 more
europepmc   +1 more source

Fab and MAb binding to DENV-1 RVPs.

, 2014
(A) E106 MAb binding to DENV-1 RVPs by bio-layer interferometry. E106 MAb binds with high apparent affinity to DENV-1 RVPs (KDapp of 13±2 nM) with a slow dissociation (t1/2>400 sec). Raw data is in red and fits are in gray. (B) Direct binding of E106 Fab
Michael S. Diamond (106070), Christopher A. Nelson (129930), Elizabeth A. Christian (553448), Joseph Rucker (553449), Syd Johnson (129934), Swati Mukherjee (493224), Theodore C. Pierson (129937), S. Kyle Austin (129925), Bimmi Shrestha (129929), Daved H. Fremont (46679), Kimberly A. Dowd (129927), Manu N. Mabila (553447), Melissa A. Edeling (129933)   +12 more
core   +1 more source