Results 31 to 40 of about 20,792 (192)

Temporally integrated single cell RNA sequencing analysis of controlled and natural primary human DENV-1 infections [PDF]

, 2020
AbstractControlled dengue human infection studies present an opportunity to address many longstanding questions in the field of flavivirus biology. However, limited data are available on how the immunological and transcriptional response elicited by an attenuated challenge virus compares to that associated with a wild-type DENV infection.
Adam T. Waickman, Heather Friberg, Gregory D. Gromowski, Wiriya Rutvisuttinunt, Tao Li, Hayden Siegfried, Kaitlin Victor, Michael K. McCracken, Stefan Fernandez, Anon Srikiatkhachorn, Damon W. Ellison, Richard G. Jarman, Stephen J. Thomas, Alan L. Rothman, Timothy P. Endy, Jeffrey R. Currier   +15 more
openalex   +3 more sources

Clinical, Serological, and Molecular Profile of Dengue Patients With Warning Signs During the 2024 Outbreak in Belo Horizonte, Brazil. [PDF]

J Med Virol
ABSTRACT Dengue poses a significant arboviral threat in Brazil, with 2024 recording the largest outbreak to date. This prospective observational study was conducted during the 2024 outbreak with unvaccinated patients at Eduardo de Menezes Hospital, Belo Horizonte.
Pereira SH, Franco-Luiz APM, Nogueira CT, Cornélio GOV, Nogueira AMC, Andrade VA, Carvalho SH, Torres KCL, Peruhype-Magalhães V, Martins-Filho OA, Coelho-Dos-Reis JGA, Teixeira-Carvalho A, da Fonseca FG, Alves PA.   +13 more
europepmc   +2 more sources

Phylogenetic and Phylogeographic Analysis of DENV-1 Genotype Ⅰ in Asian-Pacific Region [PDF]

E3S Web of Conferences, 2020
Objective: To clarify the evolutionary characteristics and transmission mode of DENV-1 genotype I dengue virus in the Asia-Pacific region. Methods: 200 DENV-1 genotype I dengue viruses in the Asia-Pacific region from 2010 to 2014 and 2015 to 2019 were used for phylogenetic analysis and bayesian phylogeographic analysis using a series of molecular ...
Yang Deyan, Wang Haiqi, Yan Bin
openaire   +2 more sources

Genome sequence analysis of dengue virus 1 isolated in Key West, Florida. [PDF]

PLoS ONE, 2013
Dengue virus (DENV) is transmitted to humans through the bite of mosquitoes. In November 2010, a dengue outbreak was reported in Monroe County in southern Florida (FL), including greater than 20 confirmed human cases.
Dongyoung Shin, Stephanie L Richards, Barry W Alto, David J Bettinardi, Chelsea T Smartt   +4 more
doaj   +1 more source

Genetic Diversity of Dengue Virus in Clinical Specimens from Bangkok, Thailand, during 2018–2020: Co-Circulation of All Four Serotypes with Multiple Genotypes and/or Clades

Tropical Medicine and Infectious Disease, 2021
Dengue is an arboviral disease highly endemic in Bangkok, Thailand. To characterize the current genetic diversity of dengue virus (DENV), we recruited patients with suspected DENV infection at the Hospital for Tropical Diseases, Bangkok, during 2018–2020.
Kanaporn Poltep, Juthamas Phadungsombat, Emi E. Nakayama, Nathamon Kosoltanapiwat, Borimas Hanboonkunupakarn, Witthawat Wiriyarat, Tatsuo Shioda, Pornsawan Leaungwutiwong   +7 more
doaj   +1 more source

Neutralizing and enhancing antibody responses to five genotypes of dengue virus type 1 (DENV-1) in DENV-1 patients

Journal of General Virology, 2017
Dengue virus (DENV) has four distinct serotypes, DENV-1-4, with four to six genotypes in each serotype. The World Health Organization recommends tetravalent formulations including one genotype of each serotype as safe and effective dengue vaccines. Here, we investigated the impact of genotype on the neutralizing antibody responses to DENV-1 in humans ...
Atsushi, Yamanaka, Meng Ling, Moi, Tomohiko, Takasaki, Ichiro, Kurane, Eiji, Konishi   +4 more
openaire   +2 more sources

DENGUE OUTBREAK IN MATO GROSSO STATE, MIDWESTERN BRAZIL

Revista do Instituto de Medicina Tropical de São Paulo, 2015
Dengue virus (DENV) is the most frequent arbovirus worldwide. In this study, we report a large outbreak in Mato Grosso State (MT). Serum samples from 604 patients with acute febrile illness for less than five days were inoculated in C6/36 cells, then ...
Letícia Borges da Silva HEINEN, Nayara ZUCHI, Belgath Fernandes CARDOSO, Marcelo Adriano Mendes dos SANTOS, Mauricio Lacerda NOGUEIRA, Renata DEZENGRINI-SLHESSARENKO   +5 more
doaj   +1 more source

Development of a Dengue Virus Serotype-Specific Non-Structural Protein 1 Capture Immunochromatography Method

Sensors, 2021
Four serotypes of dengue virus (DENV), type 1 to 4 (DENV-1 to DENV-4), exhibit approximately 25–40% of the difference in the encoded amino acid residues of viral proteins.
Kanaporn Poltep, Emi E. Nakayama, Tadahiro Sasaki, Takeshi Kurosu, Yoshiki Takashima, Juthamas Phadungsombat, Nathamon Kosoltanapiwat, Borimas Hanboonkunupakarn, Sarin Suwanpakdee, Hisham A. Imad, Narinee Srimark, Chiaki Kitamura, Atsushi Yamanaka, Akio Okubo, Tatsuo Shioda, Pornsawan Leaungwutiwong   +15 more
doaj   +1 more source

DENV-1 infection with rhabdomyolysis in an adolescent: A case report and review of challenge in early diagnosis and treatment. [PDF]

Heliyon
Dengue infection is a well-known tropical disease that has become a global health issue. The clinical characteristics of dengue range from asymptomatic to severe, which can involve multiple organs and challenge management. Rhabdomyolysis in dengue infection is a rare condition described in children and adolescents.
Putri A, Arunsodsai W, Hattasingh W, Sirinam S.   +3 more
europepmc   +4 more sources

Emergence of the Asian genotype of DENV-1 in South India

Virology, 2017
A large outbreak of dengue occurred in Tamil Nadu, South India in 2012 with 12,000 cases and CFR of 0.5%. Molecular characterization of virus present in the sera of dengue patients was undertaken to determine if there were changes in the virus population.
D, Cecilia, J A, Patil, M B, Kakade, A, Walimbe, K, Alagarasu, B, Anukumar, A, Abraham   +6 more
openaire   +2 more sources