Results 71 to 80 of about 29,720,759 (240)
American Journal of Medical Genetics Part A, EarlyView.ABSTRACT Dengue virus (DENV) poses a serious global health challenge, particularly in cases of dengue hemorrhagic fever (DHF). Patients with preexisting mitochondrial disorders may be at increased risk for complications due to the specific impact of DENV on mitochondrial‐dependent cellular processes and immune function.
Audra N. Iness +11 more
wiley +1 more source
PLoS Pathogens, 2012 We previously developed a panel of neutralizing monoclonal antibodies against Dengue virus (DENV)-1, of which few exhibited inhibitory activity against all DENV-1 genotypes. This finding is consistent with reports observing variable neutralization of different DENV strains and genotypes using serum from individuals that experienced natural infection or
Austin, SK +8 more
openaire +5 more sources
, 2019 Clinical and laboratory outcome measures for patients with DENV-1, DENV-2 vs DENV-1 mixed with DENV-2 infection.
Hong Deng (115865) +12 more
core +1 more source
Predominance of Dengue Virus Serotype-1/Genotype-I in Eastern and Southeastern Ethiopia
VirusesWe determined the dengue virus (DENV) serotypes and genotypes in archived serum samples that were collected during the 2014–2016 and 2021 dengue outbreaks in Dire Dawa City and the Somali region in Ethiopia.
Mesfin Mengesha Tsegaye +19 more
doaj +1 more source
Population dynamics of DENV-1 genotype V in Brazil is characterized by co-circulation and strain/lineage replacement [PDF]
Archives of Virology, 2012 Following successive outbreaks of dengue fever caused predominantly by dengue virus (DENV) 2 and 3, DENV-1 is now the primary serotype circulating in Brazil. We sequenced and analyzed Brazilian DENV-1 genomes and found that all isolates belong to genotype V and are subdivided into three lineages, which were introduced during four different events.
Drumond, Betânia Paiva +4 more
openaire +4 more sources
Maltase 1 regulates DENV2 infection and life history in Aedes aegypti
Insect Science, EarlyView.Our study employed CRISPR/Cas9 to generate a MAL1 knockout strain of Aedes aegypti, demonstrating that the absence of MAL1 significantly suppresses DENV2 replication in the midgut and impairs viral transmission. The mutation also altered life‐history (hatching/pupation/emerging rates and sex‐specific survival), identifying MAL1 as a novel target for ...
Man‐Jin Li +5 more
wiley +1 more source
, 2023 The number of peptides and epitopes detected by the serum samples from dengue and Zika patients in the E and NS1 proteins of DENV-1, DENV-2, DENV-3, DENV-4, and ZIKV.
Luiz Tadeu Moraes Figueiredo (8119802) +7 more
core +1 more source
PLoS ONE, 2019 Dengue fever is caused by dengue viruses (DENV) from the Flavivirus genus and is the most prevalent arboviral disease. DENV exists in four immunogenically distinct and genetically-related serotypes (DENV-1 to 4), each subdivided in genotypes. Despite the
Rodolphe Hamel +10 more
doaj +1 more source
Iflaviruses in arthropods: when small is mighty
Insect Science, EarlyView.Many arthropod species harbor iflaviruses, which often cause covert (asymptomatic) infections, but may still affect host fitness. We review the impact of iflaviruses on arthropod fitness, immunity, behaviour as well as the iflavirus’ host range, transmission, tissue tropism and the interactions with other microorganisms within arthropods.
Annamaria Mattia +3 more
wiley +1 more source
Optimal time of detection for DENV 1, DENV 2, DENV 3 and DENV 4 serotypes.
, 2015 Panel A-C: optimal time of detection for DENV 1–3 serotypes is 30 min; panel D: optimal time of detection for DENV 4 serotype is 45 min.
Boon-Teong Teoh (409368) +7 more
core +1 more source