Results 81 to 90 of about 29,720,759 (240)

Immunological and viral determinants of dengue severity in hospitalized adults in Ha Noi, Viet Nam. [PDF]

open access: yesPLoS Neglected Tropical Diseases, 2011
The relationships between the infecting dengue serotype, primary and secondary infection, viremia and dengue severity remain unclear. This cross-sectional study examined these interactions in adult patients hospitalized with dengue in Ha Noi.158 patients
Annette Fox   +14 more
doaj   +1 more source

Liver Organoids: From Disease Modelling to Regenerative Medicine

open access: yesCell Proliferation, EarlyView.
Liver organoids provide a versatile platform for disease modelling and drug discovery, leveraging stem cells and engineering techniques. They bridge research and clinical applications, offering significant potential for advancing precision medicine and regenerative therapies for liver diseases.
Tiepeng Wang   +5 more
wiley   +1 more source

DENV-specific IgG responses and laboratory parameters of clinical disease severity in patients with acute dengue.

open access: yes, 2018
Analysis of the correlation between DENV-specific IgG responses and (A) degree of viraemia (Spearmans r = -0.25, p = 0.16) in patients with DHF, (B) degree of thrombocytopenia (Spearmans r = -0.29, p = 0.009), (C) aspartate transaminase (AST) levels ...
Clare S. Hardman (5807009)   +9 more
core   +1 more source

Emergence of new genotypes and lineages of dengue viruses during the 2012–15 epidemics in southern India

open access: yesInternational Journal of Infectious Diseases, 2019
Objectives: To genotypically characterize dengue virus (DENV) isolates among dengue-infected children from 2012–13/2014–15 outbreaks in southern India.
Syed Fazil Ahamed   +7 more
doaj   +1 more source

Contribution of endosomal proteins EHD1 and EHD4 to the HIV‐1 replication cycle

open access: yesThe FEBS Journal, EarlyView.
EHD1 and EHD4, two key trafficking proteins, regulate multiple stages of HIV‐1 infection: In producer cells, they help produce fully infectious virus particles, regulate Envelope protein incorporation in a cell‐type‐dependent manner, and limit the accumulation of antiviral IFITM proteins in virions.
Grégory Pacini   +4 more
wiley   +1 more source

The linear range for the multiplex rRT-PCR assay is shown for DENV-1 (A), DENV-2 (B), DENV-3 (C), and DENV-4 (D).

open access: yes, 2013
The linear range for the multiplex rRT-PCR assay is shown for DENV-1 (A), DENV-2 (B), DENV-3 (C), and DENV-4 (D).
Jesse J. Waggoner (404050)   +14 more
core   +1 more source

TIM-1 Ubiquitination Mediates Dengue Virus Entry

open access: yesCell Reports, 2018
Summary: Dengue virus (DENV) is a major human pathogen causing millions of infections yearly. Despite intensive investigations, a DENV receptor that directly participates in virus internalization has not yet been characterized.
Ophélie Dejarnac   +16 more
doaj   +1 more source

Conserved dimerization architecture in C‐type lectins from virus‐vector mosquitoes

open access: yesThe FEBS Journal, EarlyView.
C‐type lectins (CTLs) are involved in the detection of viral/microbial carbohydrates. We studied a family of soluble CTLs in the mosquito Aedes aegypti, which acts as a vector for viruses like dengue and Zika. Using crystallography, biophysics, and structure prediction approaches, we found that these proteins consistently pair together in the same ...
Mattia Bertinelli   +6 more
wiley   +1 more source

Dengue@Home: evaluation of a hospital in the home pathway for management of adults with dengue fever

open access: yesInternal Medicine Journal, EarlyView.
Abstract Background The rising incidence of dengue in popular travel destinations for Australians is increasing the burden on local healthcare systems. Since hospital‐based monitoring consumes significant resources, alternative models of care are needed.
Georgina Oakman   +7 more
wiley   +1 more source

Model of infectious intracellular transport of DENV-1 HW, DENV-2 NGC and DENV-2 16681 in Vero cells.

open access: yes, 2013
DENV-1 HW is internalized through the classical clathrin-mediated endocytic pathway, while DENV-2 NGC and DENV-2 16681 use a non-classical clathrin- and caveolin- independent route.
Elsa B. Damonte (308403)   +2 more
core   +1 more source

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