Results 181 to 190 of about 27,818 (210)

Small extracellular vesicles from the human endothelial cell line EA.hy 926 exert a self-cell activation and modulate DENV-2 genome replication and infection in naïve endothelial cells. [PDF]

PLoS One
Calderón-Peláez MA, Madroñero LJ, Castellanos JE, Velandia-Romero ML.   +3 more
europepmc   +1 more source

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Aedes aegypti antiviral adaptive response against DENV-2

Developmental & Comparative Immunology, 2018
Priming is the conceptual term defining memory phenomenon in innate immune response. Numerous examples of enhanced secondary immune response have been described in diverse taxa of invertebrates; which naturally lacks memory response. In mosquitoes, a previous non-lethal challenge with some specific pathogens modify their immune response against the ...
Javier, Serrato-Salas, Javier, Izquierdo-Sánchez, Martha, Argüello, Renáud, Conde, Alejandro, Alvarado-Delgado, Humberto, Lanz-Mendoza   +5 more
openaire   +2 more sources

Nanodelivery system enhances the immunogenicity of dengue-2 nonstructural protein 1, DENV-2 NS1

Vaccine, 2020
Nonstructural protein 1 (NS1) of dengue virus (DENV) is currently recognized as a dengue vaccine candidate. Unfortunately, most of non-replicating immunogens typically stimulate unsatisfactory immune responses, thus, the additional adjuvant is required.
Tuksin Jearanaiwitayakul
exaly   +3 more sources

Beyond Basicity: Discovery of Nonbasic DENV-2 Protease Inhibitors with Potent Activity in Cell Culture

Journal of Medicinal Chemistry, 2021
The viral serine protease NS2B-NS3 is one of the promising targets for drug discovery against dengue virus and other flaviviruses. The molecular recognition preferences of the protease favor basic, positively charged moieties as substrates and inhibitors, which leads to pharmacokinetic liabilities and off-target interactions with host proteases such as
Nikos Kühl, Mila M. Leuthold, Mira A. M. Behnam, Christian D. Klein   +3 more
openaire   +2 more sources

Mortality Rate and Gonotropic Cycle Serotipe Denv-2 Transovarial Transmission through Intratoracal

Indian Journal of Public Health Research & Development, 2019
Transovarial transmission is an important role of Aedes aegypti as an intermediate host. This role is one of the factors dengue virus can survive in nature during interepidemic. DENV-2 transovarial transmission is an important problem because there has been evidence of horizontal transmission of DENV-2 serotypes by vertically infected mosquitoes ...
Isna Hikmawati, Hendro Wahjono, null Martini, Soeharyo Hadisaputro, Edi Darmana, Kisdjamiatun Retna Mustika Djati, Sugeng Juwono Mardihusodo   +6 more
openaire   +1 more source

Complete Genome Amplification and Sequencing of DENV-2 Pakistani Isolates: Analysis Reveals Molecular Evolution of DENV-2

Future Virology, 2018
Amjad Ali, Habib Ahmad, Mounir G AbouHaidar, Muhammad Idrees, Ijaz Ali   +4 more
openaire   +1 more source

Emergence of a Novel Dengue Virus 3 (DENV-3) Genotype-I Coincident with Increased DENV-3 Cases in Yangon, Myanmar between 2017 and 2019

Viruses, 2021
Aung Min Soe, Mya Myat Ngwe Tun, Kyaw Zin Thant   +2 more
exaly  

Continued Circulation of DENV-2 (Genotype IV) in Delhi, India

British Microbiology Research Journal, 2016
Pankaj Sharma, Veena Mittal, Mala Chhabra, Priyanka Singh, Dipesh Bhattacharya, Srinivas Venkatesh, Arvind Rai   +6 more
openaire   +1 more source

C6-structural optimizations of 2-aryl-1H-pyrazole-S-DABOs: From anti-HIV to anti-DENV activity

Bioorganic Chemistry, 2022
Wei-Lie Xiao, Yong-Tang Zheng
exaly  

What Role Does Superficial Vimentin have During DENV-2 infection?

Future Virology, 2017
Yi Yang, Jie Yang, Xiancai Rao
openaire   +1 more source