Results 111 to 120 of about 37,373 (211)

Cross-reactive binding response of anti-peptide antibody against the sE recombinant protein of DENV-1, DENV-2 and DENV-3.

, 2016
Sera raised against each peptide group were pooled (n = 5) and the resulting immune sera were used to test the cross-reactive antibody response in ELISA.
Chit Laa Poh (167240), Kristin Kirk (2805601), William John Hannan McBride (720952), Lara Grollo (490606), Babu Ramanathan (2805598), John Aaskov (222730)   +5 more
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IMMUNOPATHOGENESIS OF DENGUE DISEASE (DENV)

There iis ia lot iof iresearch ion ithe ivaried ievolution iof idengue ivirus i(DENV) iinfection in humans. Dengue ishock isyndrome (DSS), idengue ihemorrhagic ifever i(DHF), and animal models, and human data since DENV's icellular iand itissue itropism are thought ito be isignificant idengue iillness ifactors.
openaire   +2 more sources

Generation of a bivalent dengue virus-like particle targeting DENV-1 and DENV-2 in Pichia pastoris

Indonesian Journal of Biotechnology
Dengue remains a major global health concern, with current licensed vaccines offering variable protection across the four virus serotypes and posing safety considerations related to antibody-dependent enhancement (ADE). To contribute toward improved vaccine design, we developed a bivalent virus-like particle (VLP) targeting DENV-1 and DENV-2, the two ...
Kusumawardani, Shinta, Yusuf, Muhammad, Yosua, Yosua, Syafrudin, Elza Nurrachmanita, Baroroh, Umi, Nurainy, Neni, Subroto, Toto   +6 more
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Viremia and RNAemia detected after inoculation with DENV-1 0111/2011, DENV-2 0126/2010 or DENV-4 BEL 83791.

, 2018
Rhesus macaques were subcutaneously inoculated with ~105 plaque- or focus-forming units (PFU and FFU, respectively) of DENV-1 0111/2011 (n = 5), DENV-2 0126/2010 (n = 5) or DENV-4 BEL 83791 (n = 6).
Michael Cruz (5142977), Akira Homma (294831), Clarisse Lorin (204307), Edith Lepine (5142953), Maria Beatriz Borges (5142965), Marie-Pierre Malice (5142956), Elena Caride (5142962), Ana Claudia Duarte (5142968), Pedro Fernando C. Vasconcelos (5142974), Lucile Warter (338493), Yannick Vanloubbeeck (222659), Marcos Freire (5142950), Luiz Gustavo Mendes (5142959), Renato Sergio Marchevsky (166023), Ana Maria Bispo de Filippis (352082), Sally Mossman (5142971), Ygara S. Mendes (302186)   +16 more
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Genetic diversity of dengue virus circulating in the Philippines (2014-2019) and comparison with dengue vaccine strains.

PLoS Neglected Tropical Diseases
Dengue virus has four distinct serotypes and the genetic diversity within each of the four serotypes contribute to its complexity. An important aspect of dengue molecular evolutionary studies has been the dissection of the extent and structure of genetic
John Mark Velasco, Chonticha Klungthong, Piyawan Chinnawirotpisan, Paula Corazon Diones, Maria Theresa Valderama, Susie Leonardia, Wudtichai Manasatienkij, Khajohn Joonlasak, Prinyada Rodpradit, Jennifer Mateo, Vicente Vila, Fatima Claire Navarro, Anthony Jones, Aaron Farmer, Stefan Fernandez   +14 more
doaj   +1 more source

Phylogenetic trees showing the relationship of DENV identified in AFIRE study.

, 2019
The AFIRE DENV envelope (E) gene sequences are presented as: Subject Identification Number | Country | City | Year (in bold). The reference E gene sequences retrieved from GenBank are presented as: Accession Number | Strain (if available) | Country ...
Anggraini Alam (7154699), Dwiyanti Puspitasari (4062922), Ketut Tuti Merati Parwati (7522373), Dewi Dian Sukmawati (7522349), M. M. D. E. A. H. Hapsari (7522361), Bachti Alisjahbana (270243), Dewi Murniati (7522352), I Made Gede Dwi Lingga Utama (7522355), Muhammad Karyana (49829), Nurhayati Lukman (7610627), Wahyu Nawang Wulan (7522370), Herman Kosasih (476294), C Jason Liang (7522367), I Made Susila Utama (7522343), Mulya Rahma Karyanti (4112020), Ida Laksono (7522358), Ninny Meutia (7522364), Chuen-Yen Lau (205754)   +17 more
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Dengue virus genetic diversity and lineage dynamics in Thailand: implications for surveillance and vaccine implementation

Virology Journal
Background Dengue fever, caused by dengue virus (DENV), is a major public health problem in tropical and subtropical regions. Thailand is considered endemic for dengue, and all four DENV serotypes co-circulate in this country.
Pichamon Sittikul, Ifwa Wirasit, Jittraporn Rattanamahaphoom, Pimolpachr Sriburin, Warisa Nuprasert, Kittisak Taoma, Chukiat Sirivichayakul, Kriengsak Limkittikul, Saranath Lawpoolsri, Chawarat Rotejanaprasert, Supawat Chatchen   +10 more
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Heterogeneous Co-circulation of Multiple DENV-1 and DENV-2 Genotypes during the 2023 Vietnam Outbreak

Abstract Background Dengue virus (DENV) remains a major public health burden in Vietnam, where repeated outbreaks occur against a background of complex serotype and genotype circulation. Previous outbreak investigations in Vietnam have often emphasized dominance of a single serotype, genotype, or lineage.
Melissa Alifa Da Costa, Bich Thi Hau Vu, Syin Lian Adeline Yeo, Manalaysay Jessica, Ay Betül, Kazumi Haga, Hina Horio, Islam Bakhrom Karimov, Thi Thu Thuy Nguyen, Le Khanh Hang Nguyen, Ngoc Linh Nguyen, Thi Thu Hang Pham, Lay Myint Yoshida, Yamabhai Montarop, Sujan Shresta, Mai Thi Quynh Le, Meng Ling Moi   +16 more
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Mouse models as a tool to study asymptomatic DENV infections

Frontiers in Cellular and Infection Microbiology
Asymptomatic outcome accounts for most dengue virus infections and is likely to play an important role in maintaining virus circulation, contributing to its dissemination and shortening inter-epidemic periods. While dengue immunopathogenesis, investigation of potential therapeutics, and vaccine efficacy have been widely studied, only recently have ...
Paulo Henriques, Alexandra Rosa, Helena Caldeira-Araújo, Helena Caldeira-Araújo, Ana Margarida Vigário, Ana Margarida Vigário   +5 more
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Results from in vivo studies investigating the role of ZIKV antibodies in DENV infection and on DENV antibodies in ZIKV infection.

, 2019
Left panel: In mice that had ZIKV antibodies either maternally acquired or administered before DENV infection, increased DENV viral load, cytokine production, and mortality was observed.
Byron E. Martina (6612863), Marion P. G. Koopmans (185300), Thomas Langerak (6612854), Barry Rockx (151946), Eric C. M. van Gorp (225896), Noreen Mumtaz (6612857), Vera I. Tolk (6612860)   +6 more
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