Results 31 to 40 of about 37,373 (211)

T cell immunity to infection with dengue virus in humans

Frontiers in Immunology, 2014
Dengue virus (DENV) is the etiologic agent of dengue fever, the most significant mosquito-borne viral disease in humans. Up to 400 million DENV infections occur every year, and severity can range from asymptomatic to an acute self-limiting febrile ...
Daniela eWeiskopf, Alessandro eSette
doaj   +1 more source

Genetic Diversity of Dengue Virus in Clinical Specimens from Bangkok, Thailand, during 2018–2020: Co-Circulation of All Four Serotypes with Multiple Genotypes and/or Clades

Tropical Medicine and Infectious Disease, 2021
Dengue is an arboviral disease highly endemic in Bangkok, Thailand. To characterize the current genetic diversity of dengue virus (DENV), we recruited patients with suspected DENV infection at the Hospital for Tropical Diseases, Bangkok, during 2018–2020.
Kanaporn Poltep, Juthamas Phadungsombat, Emi E. Nakayama, Nathamon Kosoltanapiwat, Borimas Hanboonkunupakarn, Witthawat Wiriyarat, Tatsuo Shioda, Pornsawan Leaungwutiwong   +7 more
doaj   +1 more source

DENV-specific IgA contributes protective and non-pathologic function during antibody-dependent enhancement of DENV infection

PLOS Pathogens, 2023
Dengue represents a growing public health burden worldwide, accounting for approximately 100 million symptomatic cases and tens of thousands of fatalities yearly. Prior infection with one serotype of dengue virus (DENV) is the greatest known risk factor for severe disease upon secondary infection with a heterologous serotype, a risk which increases as ...
Adam D. Wegman, Mitchell J. Waldran, Lauren E. Bahr, Joseph Q. Lu, Kristen E. Baxter, Stephen J. Thomas, Adam T. Waickman   +6 more
openaire   +3 more sources

Bayesian Skyline plot of the CAM DENV-1 and DENV-2 lineages.

, 2023
Upper and lower panels show the Bayesian Skyline plots (BSPs) obtained from the time-scaled phylogenetic analyses of the DENV-1 and DENV-2 CCNA lineages.
Irma López Martínez (8555781), Lorena Preciado-Llanes (6756047), Adnan Araiza Rodriguez (16943087), Claudia Wong Arámbula (16943090), Julien Thézé (6433850), Mauricio Vázquez Pichardo (16943099), Oliver G. Pybus (8098271), Bernardo Gutierrez (6453725), Fabiola Garces Ayala (16943081), Sumali Bajaj (8971151), Abril Paulina Rodriguez Maldonado (16943078), Moritz U. G. Kraemer (3290625), María de la Luz Torre Rodriguez (16943084), Ernesto Ramírez González (16943093), Marina Escalera-Zamudio (606283), Darlan da Silva Candido (6433859), José Alberto Díaz-Quiñónez (16943096), Arturo Reyes-Sandoval (174899), Nuno R. Faria (8098247), Sarah C. Hill (3311418)   +19 more
core   +1 more source

Discrepant Activation Pattern of Inflammation and Pyroptosis Induced in Dermal Fibroblasts in Response to Dengue Virus Serotypes 1 and 2 and Nonstructural Protein 1

Microbiology Spectrum, 2023
Four serotypes of dengue virus (DENV-1 to DENV-4) cause mild to severe disease in humans through infected mosquito bites. Dermal fibroblasts were found to be susceptible to DENV, and this may play a critical role in establishing the initial infection ...
Kai-Che Wei, Wan-Ju Wei, Ching-Len Liao, Tsung-Hsien Chang   +3 more
doaj   +1 more source

Re-emergence of dengue virus serotype 3 infections in Gabon in 2016–2017, and evidence for the risk of repeated dengue virus infections

International Journal of Infectious Diseases, 2020
Objectives: Dengue outbreaks, mainly caused by dengue virus serotype 2 (DENV-2), occurred in 2007 and in 2010 in Gabon, Central Africa. However, information on DENV infections has been insufficient since 2010. The aim of this study was to investigate the
Haruka Abe, Yuri Ushijima, Marguerite M. Loembe, Rodrigue Bikangui, Georgelin Nguema-Ondo, Patrick I. Mpingabo, Vahid R. Zadeh, Christelle M. Pemba, Yohei Kurosaki, Yui Igasaki, Sophia G. de Vries, Martin P. Grobusch, Selidji T. Agnandji, Bertrand Lell, Jiro Yasuda   +14 more
doaj   +1 more source

Development of a Dengue Virus Serotype-Specific Non-Structural Protein 1 Capture Immunochromatography Method

Sensors, 2021
Four serotypes of dengue virus (DENV), type 1 to 4 (DENV-1 to DENV-4), exhibit approximately 25–40% of the difference in the encoded amino acid residues of viral proteins.
Kanaporn Poltep, Emi E. Nakayama, Tadahiro Sasaki, Takeshi Kurosu, Yoshiki Takashima, Juthamas Phadungsombat, Nathamon Kosoltanapiwat, Borimas Hanboonkunupakarn, Sarin Suwanpakdee, Hisham A. Imad, Narinee Srimark, Chiaki Kitamura, Atsushi Yamanaka, Akio Okubo, Tatsuo Shioda, Pornsawan Leaungwutiwong   +15 more
doaj   +1 more source

Placental Transfer of Dengue Virus (DENV)–Specific Antibodies and Kinetics of DENV Infection–Enhancing Activity in Brazilian Infants [PDF]

Journal of Infectious Diseases, 2016
Maternal-fetal transferred dengue virus (DENV)-specific antibodies have been implicated in the immunopathogenesis of dengue during infancy.A prospective birth cohort was established in a dengue-endemic area in the Northeast Region of Brazil. DENV-specific immunoglobulin G (IgG) and DENV-1-4 serotype-specific neutralizing antibody (NAb) levels were ...
Priscila M S, Castanha, Cynthia, Braga, Marli T, Cordeiro, Ariani I, Souza, Claudeir D, Silva, Celina M T, Martelli, Willem G, van Panhuis, Eduardo J M, Nascimento, Ernesto T A, Marques   +8 more
openaire   +2 more sources

Dengue outbreaks in Taiwan, 1998-2017: Importation, serotype and temporal pattern

Asian Pacific Journal of Tropical Medicine, 2018
Objective: To ascertain the role of imported cases and serotypes on dengue outbreaks in Taiwan which have been sporadic yet highly volatile during the past two decades, exhibiting record-breaking magnitude in recent years.
Ying-Hen Hsieh
doaj   +1 more source

DENV-neutralizing antibody responses detected after infection with DENV-1 0111/2011, DENV-2 0126/2010 or DENV-4 BEL 83791.

, 2018
Sera collected 2 weeks after DENV inoculation were tested by plaque-reduction neutralization test (PRNT) for their neutralizing activity against DENV-1 60305, DENV-2 44/2, DENV-3 16562 and DENV-4 TVP360.
Michael Cruz (5142977), Akira Homma (294831), Clarisse Lorin (204307), Edith Lepine (5142953), Maria Beatriz Borges (5142965), Marie-Pierre Malice (5142956), Elena Caride (5142962), Ana Claudia Duarte (5142968), Pedro Fernando C. Vasconcelos (5142974), Lucile Warter (338493), Yannick Vanloubbeeck (222659), Marcos Freire (5142950), Luiz Gustavo Mendes (5142959), Renato Sergio Marchevsky (166023), Ana Maria Bispo de Filippis (352082), Sally Mossman (5142971), Ygara S. Mendes (302186)   +16 more
core   +1 more source