Results 61 to 70 of about 37,373 (211)

Host immune response against DENV and ZIKV infections

Frontiers in Cellular and Infection Microbiology, 2022
Dengue is a major public health concern, affecting almost 400 million people worldwide, with about 70% of the global burden of disease in Asia. Despite revised clinical classifications of dengue infections by the World Health Organization, the wide spectrum of the manifestations of dengue illness continues to pose challenges in diagnosis and patient ...
Shamala Devi Sekaran, Amni Adilah Ismail, Gaythri Thergarajan, Chandramathi Samudi, Shakila Rahman, Ravishankar Ram Mani, Felicita Jusof, Yvonne A. L. Lim, Rishya Manikam   +8 more
openaire   +4 more sources

Cross-reactive DENV-specific serum neutralization during secondary DENV infections.

, 2012
A. DENV-specific neutralization of the serum at 3 months post-onset of symptoms in 2° DENV-3 infections. Longitudinal serum samples, obtained 3 months post-onset of symptoms from a subset (n = 20) of 2° DENV-3 infections, were analyzed in a flow ...
Eva Harris (27355), Marie O. Pohl (176426), Angel Balmaseda (109173), Magelda Montoya (176423), Simona Zompi (176420)   +4 more
core   +1 more source

Pro- and anti-inflammatory cytokines signatures at different severity of dengue infection

Journal of Family Medicine and Primary Care
Context: Dengue disease severity and progression are determined by the host immune response, with both pro- and anti-inflammatory cytokines are key mediators.
Himani Prajapati, Vivek Kumar, Garima Mittal, Yogesh Saxena   +3 more
doaj   +1 more source

Regional DENV serotype distribution.

, 2013
Regional data extracted from source documents for distribution of DENV-1, 2 and 3 serotypes. DENV-4 was not present in Brazil until 2011.DENV, dengue viruses.
João Bosco Siqueira, Jr (499712), Maria Glória Teixeira (248091), Germano L. C. Ferreira (499713), Lucia Bricks (499714), Graham Joint (499715)   +4 more
core   +1 more source

In silico screening of potential plant peptides against the non-structural proteins of dengue virus

Journal of Vector Borne Diseases
Background & objectives: Peptides isolated from different sources of plants have the advantages of specificity, lower toxicity, and increased therapeutic effects; hence, it is necessary to search for newer antivirals from plant sources for the treatment ...
G Reena, R Ranjani, D Goutham, K Sangeetha   +3 more
doaj   +1 more source

Emergence of genotype Cosmopolitan of dengue virus type 2 and genotype III of dengue virus type 3 in Thailand. [PDF]

PLoS ONE, 2018
Dengue is a mosquito-borne disease that has spread to over 100 countries. Dengue fever is caused by dengue virus (DENV), which belongs to the Flavivirus genus of the family Flaviviridae. DENV comprises 4 serotypes (DENV-1 to DENV-4), and each serotype is
Juthamas Phadungsombat, Marco Yung-Cheng Lin, Narinee Srimark, Atsushi Yamanaka, Emi E Nakayama, Visal Moolasart, Patama Suttha, Tatsuo Shioda, Sumonmal Uttayamakul   +8 more
doaj   +1 more source

(E)-Guggulsterone Inhibits Dengue Virus Replication by Upregulating Antiviral Interferon Responses through the Induction of Heme Oxygenase-1 Expression

Viruses, 2021
Dengue virus (DENV) infection, which causes dengue fever, dengue hemorrhagic fever, and dengue shock syndrome, is a severe global health problem in tropical and subtropical areas. There is no effective vaccine or drug against DENV infection.
Wei-Chun Chen, Chih-Ku Wei, Monir Hossen, Yao-Chin Hsu, Jin-Ching Lee   +4 more
doaj   +1 more source

Functional properties of DENV EDIII-reactive antibodies in human DENV-1-infected sera and rabbit antiserum to EDIII

Molecular Medicine Reports, 2016
The envelope domain III (EDIII) of the dengue virus (DENV) has been confirmed to be involved in receptor binding. It is the target of specific neutralizing antibodies, and is considered to be a promising subunit dengue vaccine candidate. However, several recent studies have shown that anti‑EDIII antibodies contribute little to the neutralizing or ...
Jing, Chen, Kun, Wen, Xiao-Quan, Li, Hai-Su, Yi, Xi-Xia, Ding, Yan-Fen, Huang, Yu-Xian, Pan, Dong-Mei, Hu, Biao, Di, Xiao-Yan, Che, Ning, Fu   +10 more
openaire   +3 more sources

Detection of genotype-1 of dengue virus serotype 3 for the first time and complete genome analysis of dengue viruses during the 2018 epidemic in Mandalay, Upper Myanmar.

PLoS ONE, 2021
BackgroundDengue (DEN) is a neglected tropical disease, and surveillance of dengue virus (DENV) serotypes and genotypes is critical for the early detection of outbreaks.
Mya Myat Ngwe Tun, Aung Kyaw Kyaw, Takeshi Nabeshima, Aung Min Soe, Khine Mya Nwe, Kyaw Ko Ko Htet, Thet Htoo Aung, Thein Thein Htwe, Thidar Aung, Su Su Myaing, Tu Tu Mar, Ei Phyu Lwin, Hlaing Myat Thu, Kyaw Zin Thant, Kouichi Morita   +14 more
doaj   +1 more source

Dengue virus neutralizing antibody levels associated with protection from infection in thai cluster studies. [PDF]

PLoS Neglected Tropical Diseases, 2014
Long-term homologous and temporary heterologous protection from dengue virus (DENV) infection may be mediated by neutralizing antibodies. However, neutralizing antibody titers (NTs) have not been clearly associated with protection from infection.Data ...
Darunee Buddhari, Jared Aldstadt, Timothy P Endy, Anon Srikiatkhachorn, Butsaya Thaisomboonsuk, Chonticha Klungthong, Ananda Nisalak, Benjawan Khuntirat, Richard G Jarman, Stefan Fernandez, Stephen J Thomas, Thomas W Scott, Alan L Rothman, In-Kyu Yoon   +13 more
doaj   +1 more source