The DNases of pathogenic Lancefield streptococci [PDF]
DNases are abundant among the pathogenic streptococci, with most species harbouring genes for at least one. Despite their prevalence, however, the role for these extracellular enzymes is still relatively unclear.
Alex Remmington, Claire E. Turner, Lacks
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SFN sensitizes PD‐1 blockade therapy in preclinical and clinical investigations, with no side effects. SFN elevates the antitumor response in peripheral and tumor microenvironment. ABSTRACT Anti‐PD‐1/PD‐L1 therapy has achieved promising success across several tumor types; however, its efficacy is still far from satisfactory in non–small cell lung ...
Jieyao Li +16 more
wiley +1 more source
Summary Background and objectives Systemic sclerosis (SSc) is a rare, chronic autoimmune disease characterized by fibrosis of the skin and/or internal organs. Emerging evidence suggests that subcutaneous adipose tissue may contribute to systemic inflammation and fibrosis in SSc.
Marija Geroldinger‐Simić +3 more
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Deoxyribonucleases expressed in competence-induced com and spo0 mutants of Bacillus subtilis [PDF]
The inclusion of 1% casein in buffer used to reactivate enzymes subjected to SDS-polyacrylamide electrophoresis resulted in faster and more complete restoration of nuclease and B-galactosidase enzyme activities.
McGrew, Billy Robert
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Alternative Approaches to Combat Medicinally Important Biofilm-Forming Pathogens [PDF]
Bacteria have developed the capability to produce structured communities (or cluster of cells) via adherence to surface to form biofilms that facilitate or prolong their survival under extreme environmental condition.
Palanisamy, Navindra Kumari +2 more
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Reactivation of nucleases with peroxidation damages induced by a menadione:ascorbate combination devastates human prostate carcinomas: ultrastructural aspects [PDF]
INTRODUCTION: Xenografts of androgen-independent human DU145 prostate metastatic carcinomas implanted in nu/nu male mice have revealed a significant survival after a prooxidant anticancer treatment consisting of a combination of menadione bisulfite and ...
Gilloteaux, Jacques +3 more
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Deoxyribonuclease probing on sea urchin embryo chromatin [PDF]
Bibliography: pages 118-143.The role that the sea urchin, Parechinus angulosus, embryo and sperm histone variants play in chromatin structure has been investigated. Chromatin structure has been determined at different levels of resolution in sperm and in
Landsman, David
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Failure to process chromatin on apoptotic microparticles in the absence of deoxyribonuclease 1 like 3 drives the development of systemic lupus erythematosus [PDF]
Systemic lupus erythematosus is an autoinflammatory disorder driven by the development of autoantibodies to self-nucleic acids, in particular to DNA and to chromatin.
Sally, Benjamin Andrew
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Modeling the influence of DNA lesion on the regulation of gene expression [PDF]
Nucleic acids are organic macromolecules that result from the polymerization of nucleotides. These molecules are generally considered as the support of the genetic information. Two families of nucleic acids are currently known: DNA and RNA.
MICLOT, Tom
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Purification & Characterization of a Deoxyribonuclease from Etiolated Soybean [PDF]
A deoxyribonuclease (DNase) has been isolated from a purified preparation of soybean nuclei. The procedure, involving solubilization of proteins using ammonium sulfate, Sephadex G-75, DEAE-Cellulose and CMSephadex chromatography and non-denaturing ...
Xu, Cunyong
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