Results 21 to 30 of about 4,381 (137)

GHRHR Deficiency Enhances Retinal Ganglion Cell Survival and Visual Functions in Experimental Glaucoma by Inhibiting Ferroptosis

open access: yesAdvanced Science, EarlyView.
Glaucoma, a major cause of blindness, involves retinal ganglion cell (RGC) degeneration. This study shows growth hormone‐releasing hormone receptor (GHRHR) deficiency preserves RGC survival and restores vision, unlike activation which only aids survival.
Yan Tong   +24 more
wiley   +1 more source

Development And Evaluation Of Terbutaline Sulphate Loaded-Biodegradable Microspheres For Pulmonary Delivery [PDF]

open access: yes, 2007
Mikrosfera terbutalin sulfat (TBS) pelepasan tertahan dibangun menggunakan polimer PLA R 203H dan PLGA RG 504H. Sustained-release terbutaline sulphate (TBS) microspheres were developed using PLA R 203H and PLGA RG 504H ...
Mohammed Ahmed, Rehab Abdallah
core  

Apoptosis of Cardiomyosites in Heart Disease [PDF]

open access: yes, 2023
Although the notion that apoptosis can act as a pathogenic mediator came somewhat later to car-diovascular medicine than to other fields of medicine, research into the role of apoptosis in heart disease has progressed explosively during the past 10 years.
Maxmudovich, Ziyodullaev Maqsud
core   +2 more sources

The Trichinella Super‐Pangenome Reveals the Evolution of Encapsulation and Predicted Host–Parasite Protein Interactions

open access: yesAdvanced Science, EarlyView.
ABSTRACT The muscle capsule of Trichinella is a critical structure that impedes immune attacks and drug penetration, yet the molecular mechanisms underlying its formation remain poorly understood. Using a high‐quality super‐pangenome comprising 12 Trichinella species, we compared extensive genomic variations between encapsulating and non‐encapsulating ...
Qingbo Lv   +8 more
wiley   +1 more source

COELENTERATE TOXINS, ITS PHARMACEUTICAL AND THERAPEUTIC EFFECTS [PDF]

open access: yes, 2021
Present review article emphasizes species specific coelenterate toxins, its pharmaceutical and therapeutic effects. Most of the coelenterates inflict venom accidently by using nematocysts found on arms.
SHARMA, SIMRAN, UPADHYAY, RAVI KANT
core   +1 more source

NET‐DNA Activates the ANXA2/TMEM215/BiP Axis to Promote Mitophagy‐Mediated Anoikis Resistance in Endometriosis

open access: yesAdvanced Science, EarlyView.
NET‐DNA is enriched during early endometriotic lesion establishment and drives anoikis resistance by promoting an ANXA2–TMEM215–BiP axis. This pathway strengthens ER–mitochondria contacts, enhances PINK1/Parkin‐associated mitophagy, preserves mitochondrial homeostasis, and supports ectopic stromal cell survival, thereby facilitating lesion persistence ...
Honglin Wang   +12 more
wiley   +1 more source

Dasatinib and quercetin prevent alveolar bone loss in aged mice

open access: yesJournal of Periodontology, EarlyView.
Abstract Background Recent findings have associated alveolar bone loss (ABL) with the presence of senescent cells. Aging and the accumulation of senescent cells are associated with a pro‐inflammatory environment which may exacerbate tissue damage.
Luisa S. Battistelli   +7 more
wiley   +1 more source

Chloroplast ribonuclease P does not utilize the ribozyme-type pre-tRNA cleavage mechanism. [PDF]

open access: yes, 2000
This is the published version. Copyright 2000 by the RNA Society.The transfer RNA 5' maturation enzyme RNase P has been characterized in Bacteria, Archaea, and Eukarya.
Thomas, Brian C.   +2 more
core   +1 more source

DNA End Resection Controls the Balance between Homologous and Illegitimate Recombination in Escherichia coli [PDF]

open access: yes, 2012
Even a partial loss of function of human RecQ helicase analogs causes adverse effects such as a cancer-prone Werner, Bloom or Rothmund-Thompson syndrome, whereas a complete RecQ deficiency in Escherichia coli is not deleterious for a cell.
A Kuzminov   +59 more
core   +3 more sources

Characterization of Point Mutations in the cdtA Gene of the Cytolethal Distending Toxin of Actinobacillus Actinomycetemcomitans [PDF]

open access: yes, 2005
The Cdt is a family of gram-negative bacterial toxins that typically arrest eukaryotic cells in the G0/G1 or G2/M phase of the cell cycle. The toxin is a heterotrimer composed of the cdtA, cdtB and cdtC gene products.
Cao, Linsen   +4 more
core   +6 more sources

Home - About - Disclaimer - Privacy