Nucleases and Their Inhibitors: Exploring Biological Roles, Industrial Applications, and Challenges in Heterologous Expression. [PDF]
Graphical Abstract and Lay Summary Intracellular nucleases, depicted as blue circles in a nucleosome, hydrolyze phosphodiester bonds, repair damaged DNA using DNA base excision repair (BER), mismatch repair (MMR), and homologous recombination (HR), and are involved in DNA replication.
Vermeulen W, van Staden ADP, Dicks LMT.
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Fluorescent Analysis of K<sub>M</sub> and V<sub>max</sub> Values for Methyl-Dependent Restriction Endonucleases. [PDF]
Martyshova V, Sedykh S.
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DNA recognition, cleavage, and toxic metal ion interaction of an artificial zinc finger protein inside E. coli cells. [PDF]
Hajdu B +8 more
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The interplay between supercoiling and DNA modifying enzymes at the single-molecule level. [PDF]
Wilkinson EM +4 more
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Ancestral proteins trace the emergence of substrate specificity and oligomerization within bacterial DEDDy dinucleases. [PDF]
Mortensen S +5 more
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Polymorphism analysis of estrogen receptor β Gene RsaI and AluI in girls with idiopathic central precocious puberty: investigating the relationship and implications for early risk prediction. [PDF]
Liu P +5 more
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Viral Nuclease Inhibitors: Small molecule disruptors of the UL12 alkaline nuclease display broad anti-herpes virus activity. [PDF]
Sharma N +10 more
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AlphaFold3-guided optimization of a photoactivatable endonuclease for top-down genome engineering. [PDF]
Yone H, Kono H, Sato M, Ohta K.
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VDR BsmI polymorphism and obesity in vitamin D deficiency among undergraduate students: a cross-sectional study. [PDF]
Rubio DAV +9 more
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Molecular Characterization of a Restriction Endonuclease PsaI from <i>Pseudomonas anguilliseptica</i> KM9 and Sequence Analysis of the PsaI R-M System. [PDF]
Furmanek-Blaszk B, Mruk I, Sektas M.
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