Results 1 to 10 of about 4,381 (137)
Advanced Materials, EarlyView.An injectable cold atmospheric plasma‐activated decellularized tumor extracellular matrix hydrogel is introduced as a post‐surgical immunoactivation platform. The engineered gel attracts residual tumor cells and induces immunogenic cell death, reshaping the tumor microenvironment and eliciting systemic antitumor immunity. In combination with checkpoint
Tianxu Fang +5 more
wiley +1 more source
An Endonuclease Excising 8-Oxo-2'-deoxyguanosine in Regenerating Rat Liver [PDF]
, 2004 Oxidative DNA damage is generated in every tissue in the body, and is mainly excised by glycosylases. However, endonucleases and exonucleases are suggested as being present in tissues, since oxidized nucleosides such as thymidine glycol and 8-Oxo-2 ...
Baba, Naomichi +3 more
core
Novel Antibiofilm Non-Biocidal Strategies [PDF]
, 2021 Subaerial biofilm (SAB) formation on cultural heritage objects is often considered an undesirable process in which microorganisms and their by-products, e.g., enzymes and pigments, cause damage or alteration to a surface.
F. Cappitelli, F. Villa
core +1 more source
Advanced Science, EarlyView.A flexible, ultrathin multi‐channel microelectrode array (MEA) conformally integrated onto a curved slide‐well enables stable electrical interfacing with 3D cardiac organoids. The geometry‐guided self‐alignment allows simultaneous recording of extracellular field potentials and contractile motion from irregular, beating tissues.
Ye Seul Kim +12 more
wiley +1 more source
Cellular and Secretory Proteins of the Salivary Glands of \u3cem\u3eSciara coprophila\u3c/em\u3e During the Larval-pupal Transformation [PDF]
, 1972 The cellular and secretory proteins of the salivary gland of Sciara coprophila during the stages of the larval-pupal transformation were examined by electrophoresis in 0.6 mm sheets of polyacrylamide gel with both SDS-continuous and discontinuous buffer ...
Been, Anita Cavagnaro, Rasch, Ellen M.
core +1 more source
The Toxic Effects of Aflatoxin B1: An Update [PDF]
, 2019 Aflatoxin B1 (AFB1) is the most toxic in aflatoxin family. It is well known for its involvement in hepatic carcinogenesis. Other adverse effects include immune weakness, reproduction deficiency, malnutrition, and growth impairment.
Shan, Yuhua
core +1 more source
Advanced Science, EarlyView.This study developed a hierarchical targeting nanoplatform, siTREM2@ETP‐PEOz‐OMVs, against triple‐negative breast cancer (TNBC) bone metastasis. It precisely delivers therapeutic siTREM2 to monocytes/macrophages within the metastatic niche. This intervention dually regulates cell fate: reprogramming immunosuppressive macrophages and inhibiting ...
Fanglu Chen +12 more
wiley +1 more source
Codominance and toxins: A path to drugs of nearly unlimited selectivity [PDF]
, 1995 The effectiveness of drugs is often limited by their insufficient selectivity. I propose designs of therapeutic agents that address this problem. The key feature of these reagents, termed comtoxins (codominance-mediated toxins), is their ability to ...
Varshavsky, Alexander
core
Advanced Science, EarlyView.Cer24:1 levels are reduced in neutrophilic asthma and inversely correlate with disease severity and airway neutrophilia. Restoring Cer24:1 suppresses pathogenic Th17 differentiation by engaging EP2 on CD4+ T cells, thereby dampening the JAK2–STAT3–RORγt axis and reducing IL‐17 production.
Huan Liu +11 more
wiley +1 more source
Breed differences in PCV2 uptake and disintegration in porcine monocytes [PDF]
, 2018 Porcine circovirus type 2 (PCV2) is associated with various diseases which are designated as PCV2-associated diseases (PCVADs). Their severity varies among breeds.
Huang, Liping +4 more
core +2 more sources