Effect of deoxyribonuclease-deficiency on myeloid cells under homeostatic and inflammatory conditions [PDF]
, 2022 In healthy and diseased individuals, endogenous nucleic acids are present in various forms and need to be processed and cleared. Failed clearance of DNA is associated with an autoimmune disease termed systemic lupus erythematosus (SLE), which is ...
Reuter, Tatjana
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The role of the host—Neutrophil biology
Periodontology 2000, EarlyView., 2023 Abstract Neutrophilic polymorphonuclear leukocytes (neutrophils) are myeloid cells packed with lysosomal granules (hence also called granulocytes) that contain a formidable antimicrobial arsenal. They are terminally differentiated cells that play a critical role in acute and chronic inflammation, as well as in the resolution of inflammation and wound ...
Iain L. C. Chapple +4 more
wiley +1 more source
Restriction-modification system with methyl-inhibited base excision and abasic-site cleavage activities [PDF]
, 2015 The restriction-modification systems use epigenetic modification to distinguish between self and nonself DNA. A modification enzyme transfers a methyl group to a base in a specific DNA sequence while its cognate restriction enzyme introduces breaks in ...
Fukuyo, Masaki +9 more
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Quo Vadis Venomics? A Roadmap to Neglected Venomous Invertebrates [PDF]
, 2014 This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. (CC BY 4.0).
Campbell, L, Jenner, R, von Reumont, B
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The Enzymology and Genetics of Dna Repair in Drosophila Melanogaster (Ap Endonucleases, Oregon-R, Mus(2)201, Cleavage Mechanisms). [PDF]
, 1985 The work presented herein investigates the repair of apurinic/apyrimidinic (AP) sites in Drosophila melanogaster. Two different AP endonucleases were isolated differing in pH optima, reaction requirements, and associated activities.
Spiering, Andrea Lynn
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Red light delays programmed cell death in non-host interaction between Pseudomonas syringae pv tomato DC3000 and tobacco plants [PDF]
, 2020 Light modulates almost every aspect of plant physiology, including plant-pathogen interactions. Among these, the hypersensitive response (HR) of plants to pathogens is characterized by a rapid and localized programmed cell death (PCD), which is critical ...
Carrau, Analía +6 more
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What did CRISPR-Cas9 accomplish in its first 10 years? [PDF]
, 2023 It’s been 10 years now from the debut of clustered regularly interspaced short palindromic repeats-associated protein 9 (CRISPR/Cas9) era in which gene engineering has never been so accessible, precise and efficient.
Khlidj, Yehya
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Mesoporous Silica-Based Supports for the Controlled and Targeted Release of Bioactive Molecules in the Gastrointestinal Tract [PDF]
, 2015 JFS Special Issue: 75 Years of Advancing Food Science, and Preparing for the Next 75Mesoporous silica particles (MSPs) have attracted increasing interest as supports in the design of controlled delivery materials.
Barat Baviera, José Manuel +3 more
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Activation of nucleases, pcd, and mobilization of reserves in the araucaria angustifolia megagametophyte during germination [PDF]
, 2018 The megagametophyte of mature seeds of Araucaria angustifolia consists of cells with thin walls, one or more nuclei, a central vacuole storing proteins, and a cytoplasm rich in amyloplasts, mitochondria and lipid bodies.
Correa, María D. +5 more
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A Genetic and Developmental Analysis of a Soluble Acid Deoxyribonuclease in Drosophila melanogaster [PDF]
, 1978 A deoxyribonuclease, called DNase-1, that is active at acid pH in the presence of EDTA has been studied in Drosophila melanogaster. The locus for the enzyme maps genetically to 61.8 on the right arm of the third chromosome.
Detwiler, Charles, MacIntyre, Ross
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