Results 141 to 150 of about 279,947 (331)
Molecular Oncology, EarlyView.Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon +9 more
wiley +1 more source
The case for cloud service trustmarks and assurance-as-a-service [PDF]
, 2013 Cloud computing represents a significant economic opportunity for Europe. However, this growth is threatened by adoption barriers largely related to trust.
Healy, Philip +5 more
core
Tumor mutational burden as a determinant of metastatic dissemination patterns
Molecular Oncology, EarlyView.This study performed a comprehensive analysis of genomic data to elucidate whether metastasis in certain organs share genetic characteristics regardless of cancer type. No robust mutational patterns were identified across different metastatic locations and cancer types.
Eduardo Candeal +4 more
wiley +1 more source
Software reliability prediction with an improved Elman network model
Tongxin xuebao, 2011 In order to improve accuracy and dependability of using neural network for software reliability prediction,a multi-objective optimization-based improved Elman recurrent network method（Mop-IElman） was proposed.First,on the basis of the Elman network,a ...
CHENG Xu-chao1, CHEN Xin-yu1, GUO Ping1
doaj
Molecular Oncology, EarlyView.Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat +8 more
wiley +1 more source
Software dependability modeling using an industry-standard architecture description language
, 2008 Performing dependability evaluation along with other analyses at architectural level allows both making architectural tradeoffs and predicting the effects of architectural decisions on the dependability of an application.
Feiler, Peter H. +3 more
core +2 more sources
An overview of fault tree analysis and its application in model based dependability analysis
Expert systems with applications, 2017 Sohag Kabir
semanticscholar +1 more source
Molecular Oncology, EarlyView.To integrate multiple transcriptomics data with severe batch effects for identifying MB subtypes, we developed a novel and accurate computational method named RaMBat, which leveraged subtype‐specific gene expression ranking information instead of absolute gene expression levels to address batch effects of diverse data sources.
Mengtao Sun, Jieqiong Wang, Shibiao Wan
wiley +1 more source
Molecular Oncology, EarlyView.Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley +5 more
wiley +1 more source