Results 41 to 50 of about 32,786 (219)
Organoids in pediatric cancer research
FEBS Letters, EarlyView.Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley +1 more source
IEEE AccessCutting-edge integrated circuits (ICs) are increasingly vulnerable to hardware faults, which can jeopardize the overall reliability of the system. Hence, it is crucial to evaluate the impact of faults to identify hardware vulnerabilities that later ...
Juan-David Guerrero-Balaguera +7 more
doaj +1 more source
Sensors, 2022 Distributed Embedded Systems (DESs) carrying out critical tasks must be highly reliable and hard in real-time. Moreover, to operate in dynamic operational contexts in an effective and efficient manner, they must also be adaptive.
Alberto Ballesteros +5 more
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FEBS Letters, EarlyView.Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho +3 more
wiley +1 more source
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
FEBS Letters, EarlyView.Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
Investigation of Amazon and Google for Fault Tolerance Strategies in Cloud Computing Services
Online Academic Journal of Information Technology, 2016 Cloud computing has recently become an attractive topic due to its ability to offer information technology solutions through virtual machines as on-demand services to share and consume resources over the Internet.
Sinan Can Açan, Shereen Al-raheym
doaj +1 more source
FEBS Letters, EarlyView.We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee +3 more
wiley +1 more source
Technological reliability of chemical engineering systems
Тонкие химические технологии, 2016 A significant part of the gross domestic product is lost because of hitches followed by long downtime periods in industrial systems. This is a common problem in the industry of developed nations.
N. N. Prokhorenko, K. O. Goncharuk
doaj +1 more source
Diversity and complexity in neural organoids
FEBS Letters, EarlyView.Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source
FEBS Letters, EarlyView.Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil +4 more
wiley +1 more source