Liquid biopsy enables minimally invasive, real‐time molecular profiling through analysis of circulating biomarkers in biological fluids. This Perspective highlights the importance of training pathologists through integrative educational programs, such as the European Masters in Molecular Pathology, to ensure effective and equitable implementation of ...
Marius Ilié +13 more
wiley +1 more source
Quantitative EEG Assessment of Dependence-Related Neurophysiological Patterns Using Rule- and Score-Based Modeling in Substance Use Disorders. [PDF]
Gürbüz MS, Gül Ö, Ekşi EF, Ögel K.
europepmc +1 more source
Potential therapeutic targeting of BKCa channels in glioblastoma treatment
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak +4 more
wiley +1 more source
Assessment of Functional Capacity and Its Sociodemographic and Health Determinants in Older Adults from a Region of Peru. [PDF]
Oblitas-Guerrero SM +6 more
europepmc +1 more source
Effective therapeutic targeting of CTNNB1‐mutant hepatoblastoma with WNTinib
WNTinib, a Wnt/CTNNB1 inhibitor, was tested in hepatoblastoma (HB) experimental models. It delayed tumor growth and improved survival in CTNNB1‐mutant in vivo models. In organoids, WNTinib outperformed cisplatin and showed enhanced efficacy in combination therapy, supporting its potential as a targeted treatment for CTNNB1‐mutated HB.
Ugne Balaseviciute +17 more
wiley +1 more source
Nicotine Dependence and Mental Health Among Syrian University Students: The Role of E-Cigarette Use: A Cross-Sectional Study. [PDF]
Alameer MB +7 more
europepmc +1 more source
Determination of fast electron energy dependence of magic angles in electron energy loss spectroscopy for anisotropic systems [PDF]
Yuekui Sun, Jun Yuan
openalex +1 more source
Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells
We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller +17 more
wiley +1 more source
The effect of sequence stability on serial dependence. [PDF]
Celin EK, Hansmann-Roth S.
europepmc +1 more source
Spectral state dependence of the 0.4-2 MeV polarized emission in Cygnus X-1 seen with INTEGRAL/IBIS, and links with the AMI radio data [PDF]
Juan Rodríguez +8 more
openalex +1 more source

