Results 151 to 160 of about 1,284,928 (317)

LINC01116, a hypoxia‐lncRNA marker of pathological lymphangiogenesis and poor prognosis in lung adenocarcinoma

Molecular Oncology, EarlyView.
The LINC01116 long noncoding RNA is induced by hypoxia and associated with poor prognosis and high recurrence rates in two cohorts of lung adenocarcinoma patients. Here, we demonstrate that besides its expression in cancer cells, LINC01116 is markedly expressed in lymphatic endothelial cells of the tumor stroma in which it participates in hypoxia ...
Marine Gautier‐Isola, Rafael Lopes Goncalves, Marin Truchi, Caroline Lacoux, Célia Scribe, Hugo Cadis, Laetitia Guardini, Sophie Bekisz, Marius Ilié, Paul Hofman, Georges Vassaux, Bernard Mari, Roger Rezzonico   +12 more
wiley   +1 more source

The Mediating Role of Emotion Dysregulation in the Association Between Impulsivity and Severity of Substance Dependence. [PDF]

Clin Psychol Psychother
Mansueto G, Palmieri S, Nikčević AV, Caselli G, Spada MM.   +4 more
europepmc   +1 more source

Evaluation and Projected Changes in Rainfall Erosivity: Topography Dependence Revealed by Convection-Permitting Climate Projections for the Mediterranean Island of Sicily

Eleonora Dallan, Vincenzo Bagarello, Vito Ferro, Vincenzo Pampalone, Marco Borga   +4 more
openalex   +1 more source

Grain Size Dependence of Active Slip Systems in an AZ31 Magnesium Alloy

, 2003
Takayuki Kobayashi, Junichi Koike, Yu Yoshida, S. Kamado, Mayumi Suzuki, Kouichi Maruyama, Yo Kojima   +6 more
openalex   +2 more sources

ATF4‐mediated stress response as a therapeutic vulnerability in chordoma

Molecular Oncology, EarlyView.
We screened 5 chordoma cell lines against 100+ inhibitors of epigenetic and metabolic pathways and kinases and identified halofuginone, a tRNA synthetase inhibitor. Mechanistically halofuginone induces an integrated stress response, with eIF2alpha phosphorylation, activation of ATF4 and its target genes CHOP, ASNS, INHBE leading to cell death ...
Lucia Cottone, James Dunford, Eleanor Calcutt, Vicki Gamble, Filiz Senbabaoglu Aksu, Lorena Ligammari, Georgina Wherry, Giorgia Gaeta, John C. Christianson, Adrienne M. Flanagan, Udo Oppermann, Adam P. Cribbs   +11 more
wiley   +1 more source

The Short Nicotine Dependence Index: A Simple and Versatile Self-Report Measure of Nicotine Dependence for General Populations. [PDF]

Nicotine Tob Res
Jackson SE, Tattan-Birch H, Stapleton J, Jarvis MJ.   +3 more
europepmc   +1 more source

Hexapod Robot Energy Consumption Dependence on Body Elevation and Step Height

, 2014
Mindaugas Luneckas, Tomas Luneckas, Dainius Udris, N. M. Fonseca Ferreira   +3 more
openalex   +2 more sources

Electron Temperature Dependence of the Optical Properties of Small Sodium Nanoparticles [PDF]

, 2014
Guozhong Wang, Yi-Zhuang Zheng, Zi Jian
openalex   +1 more source

Temperature Dependence of Aqueous-Phase Decomposition of α-Hydroxyalkyl-Hydroperoxides [PDF]

, 2020
Mingxi Hu, Kunpeng Chen, Junting Qiu, Ying‐Hsuan Lin, Kenichi Tonokura, Shinichi Enami   +5 more
openalex   +1 more source

Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma

Molecular Oncology, EarlyView.
Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken, Andrea Abel Gutierrez, Imke van Rossum, Cornelia G. Spruijt, Michiel Vermeulen, Guido van Mierlo, Blanca Scheijen, Annemiek B. van Spriel   +7 more
wiley   +1 more source