Results 181 to 190 of about 1,284,928 (317)

Phenotypic and genotypic characterization of single circulating tumor cells in the follow‐up of high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon, Rui P. L. Neves, Nikolas H. Stoecklein, Sven‐Thorsten Liffers, Jens Siveke, Jan D. Kuhlmann, Pauline Wimberger, Paul Buderath, Rainer Kimmig, Sabine Kasimir‐Bauer   +9 more
wiley   +1 more source

Mental health of caregivers for people with dementia and cerebral palsy as a key determinant of caregiver burden: a multivariable analysis. [PDF]

Front Public Health
Sánchez-Gil A, Calleja-Caballero A, Pérez-Robledo F, Martín-Sánchez C, Rodríguez-Lorenzo M, Martínez-Romo M, Pérez-Saez E, Rodríguez-Muñoz PM, Rivera-Picón C, Perez J, Sánchez-González JL.   +10 more
europepmc   +1 more source

Pressure Surge Dependence on Valve Operations in a Pipeline Loading System

, 2015
Barinaadaa Thaddeus Lebele-Alawa, Felix Ezekiel Oparadike   +1 more
openalex   +2 more sources

Combining antibody conjugates with cytotoxic and immune‐stimulating payloads maximizes anti‐cancer activity

Molecular Oncology, EarlyView.
Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang, Dong Jun Koo, Peter M. Tessier, Greg M. Thurber   +3 more
wiley   +1 more source

Differences in AUTOS- and FTND-assessed dependence on various tobacco products among Chinese current tobacco/nicotine users. [PDF]

Sci Rep
Yan D, Fei T, Liu X, Wu B, Gao Y, Li X, Li Y, Zhang Y, Jiang Y, Che Y, Zheng S.   +10 more
europepmc   +1 more source

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

Molecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee, Byung‐Cheol Han, Gi‐Bang Koo, Jihye Park, Mijin Kwon, Young Bin Park, Jae‐Mun Choi, Seung‐Ho Lee, Sangho Roh   +8 more
wiley   +1 more source

Evaluation of the relationship between insulin resistance and nicotine dependence: A cross-sectional study. [PDF]

Tob Induc Dis
Saruhan S, Kocabaş M, Tekbil GT, Sezgin Y.   +3 more
europepmc   +1 more source

Angular dependence of Auger electron emission from a single crystal specimen

, 1972
Liam A. McDonnell, D.P. Woodruff
openalex   +1 more source

What is the purpose of diagnosing addiction or dependence and what does this mean for establishing diagnostic criteria? [PDF]

, 2011
Robert West, Peter Miller
openalex   +1 more source

Density dependence [PDF]

Nature Plants, 2019
openaire   +2 more sources