Results 41 to 50 of about 1,284,928 (317)

Environmental dependence of gas properties in a protocluster at z~2.5 [PDF]

, 2021
Kohei Aoyama, Tadayuki Kodama, Tomoko L. Suzuki, Ken-ichi Tadaki, Rhythm Shimakawa, Masao Hayashi, Yusei Koyama, José Manuel Pérez-Martínez   +7 more
openalex   +1 more source

Age-related changes of dopamine D1 and D2 receptors expression in parvalbumin-positive cells of the orbitofrontal and prelimbic cortices of mice

Frontiers in Neuroscience
Dopamine (DA) plays a pivotal role in reward processing, cognitive functions, and emotional regulation. The prefrontal cortex (PFC) is a critical brain region for these processes.
Jihui Dong, Jihui Dong, Xiaoyan Wei, Xiaoyan Wei, Ziran Huang, Ziran Huang, Jing Tian, Jing Tian, Wen Zhang, Wen Zhang   +9 more
doaj   +1 more source

Parent Quality of Life at Two Years Following Their Child's Completion of Acute Lymphoblastic Leukemia Treatment

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Parents of children treated for acute lymphoblastic leukemia (ALL) often experience significant caregiver burden and disruption to their well‐being. While parent quality of life (QoL) during treatment is well characterized, little is known about outcomes during early survivorship.
Sara Dal Pra, Maria McCarthy, Michael Takagi, Cinzia De Luca   +3 more
wiley   +1 more source

Psychometric properties of the Turkish version of Drug Use Disorders Identification Test–Extended (Turkish DUDIT-E) in substance-dependent adults under probation

Psychiatry and Clinical Psychopharmacology, 2017
Objective: Motivation is a widely used concept in substance use treatment, which is related to the change during treatment. The Drug Use Disorders Identification Test–Extended (DUDIT-E) is one of the instruments to measure motivation.
Cuneyt Evren, Gokhan Umut, Muge Bozkurt, Bilge Evren, Hanife Yilmaz   +4 more
doaj   +1 more source

Evaluation of the Utility of Baseline Echocardiogram in Patients With Standard Risk Precursor B‐Lymphoblastic Leukemia

Pediatric Blood &Cancer, EarlyView.
Abstract Background A routine baseline echocardiogram is often obtained prior to anthracycline administration in children with cancer. The utility of baseline echocardiogram is unclear in patients with standard risk B‐cell acute lymphoblastic leukemia (SR B‐ALL) as their anthracycline cumulative dose is low.
Ziyad Alrajhi, Alice Pozza, Luc Mertens, Adam Paul Yan, Sarah Alexander   +4 more
wiley   +1 more source

A review of systematic reviews for evidence on use of mobile applications for mental disorders, including substance use disorders, in low and middle-income countries

Digital Health
Background and objectives There is an increased burden of mental disorders, including substance use disorders (MSUD) in low- and middle-income countries (LMICs). Digital technology offers a viable avenue to scale up the services for MSUD in such settings.
Riya Kaur Bhatia, Parag Bhardwaj, Anshika Chaudhry, Abhishek Ghosh, Arpit Parmar, Yashita Ahluwalia, Gunjan Singh, Deepshikha Prasad, Pulkit Verma, Neha Dahiya, Ashoo Grover, Siddharth Sarkar, Yatan Pal Singh Balhara   +12 more
doaj   +1 more source

CPX‐351 in High‐Risk Relapsed Pediatric Acute Leukemia: Real‐World Phase 1 Data Establishing the FDA‐Approved Dose

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background/Objectives Outcomes for pediatric relapsed/refractory (R/R) acute myeloid leukemia (AML) remain dismal. CPX‐351, a liposomal formulation of cytarabine and daunorubicin, may have less off‐target toxicities than traditional chemotherapies and has shown improved outcomes for adults with newly diagnosed therapy‐related AML.
Jonathan D. Bender, Lauren Pommert, Lori R. Backus, Andrea Bidwell, Courtney Blank, Erin H. Breese, Karen C. Burns, Adam Lane, Lynn H. Lee, Benjamin Mizukawa, Robin E. Norris, Maureen M. O'Brien, Daniel Peck, Christine Phillips, Thomas D. Ryan, Jennifer Young, Michael Absalon, John P. Perentesis   +17 more
wiley   +1 more source

Pi4KIIα Regulates Unconditioned Stimulus-Retrieval-Induced Fear Memory Reconsolidation through Endosomal Trafficking of AMPA Receptors

iScience, 2020
Summary: Targeting memory reconsolidation is an effective intervention for treating posttraumatic stress disorder (PTSD). Disrupting unconditioned stimulus (US)-retrieval-induced fear memory reconsolidation has become an effective therapeutic approach to
Hongling Guo, Kai Yuan, Zhongyu Zhang, Yanxue Xue, Wei Yan, Shiqiu Meng, Weili Zhu, Ping Wu, Yanping Bao, Jie Shi, Wen Zhang, Lin Lu, Ying Han   +12 more
doaj   +1 more source

Novel Genetic Risk Factor Identified for L‐Asparaginase‐Induced Pancreatitis in Pediatric Patients With Cancer

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background L‐asparaginase is a critical component in treatment protocols for pediatric acute lymphoblastic leukemia. Acute pancreatitis reactions can necessitate delays and, in some cases, discontinuation of L‐asparaginase, which compromises outcomes.
Edward J. Raack, Wan‐Chun Chang, Miguel Cordova‐Delgado, Spencer J. Anderson, Jessica N. Trueman, Erika N. Scott, Catrina M. Loucks, Shahrad R. Rassekh, Gabriella S. S. Groeneweg, Michelle Higginson, Kathy Li, Fudan Miao, Derek Yau, Donna Johnston, Mounira Ibrahim, Maja Krajinovic, Thai Hoa Tran, Jessica Tewfik, Jean‐François Bussières, Thaïna‐Rafi Jean‐Baptiste, Denis Lebel, Lucie Pecheux, Bina Gyawali, Gregory Guilcher, Gesche Riabowol, Geert ’t Jong, Michelle Staub, Geoff Cuvelier, Kathleen Felton, Sara Khalaj, Michael Rieder, Awatif Abuzgaia, Tamorah Lewis, Himal Ghimire, Paul Nathan, Kerry Goralski, Ketan Kulkarni, Zara Forbrigger, Colin J. D. Ross, Bruce C. Carleton   +39 more
wiley   +1 more source

Trivializing dependence [PDF]

British Journal of Addiction, 1990
AbstractThere are a number of repetitive behaviors which have in common what appears to be a decrease in an individual's capacity to choose to discontinue them. The taxonomy we select to categorize these behaviors depends on our objectives. Broad definition which label as ‘addictions’ both repetitive use of drugs and repetitive behaviors not related to
openaire   +2 more sources