Results 91 to 100 of about 3,753,934 (302)

Septin 9 PB domains coordinate centrosome positioning and microtubule acetylation to control epithelial polarity

open access: yesFEBS Letters, EarlyView.
Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai   +4 more
wiley   +1 more source

Development and initial validation of a new self-report measure to assess perceived dependence on tobacco and nicotine products

open access: yesScientific Reports
How nicotine is administered has evolved from cigarettes to various delivery systems. Assessing perceived dependence on nicotine-containing products now requires accounting for product specificity while allowing comparisons across products and users ...
Esther F. Afolalu   +6 more
doaj   +1 more source

Nonparametric Estimation of the Tail-Dependence Coefficient

open access: yesRevstat Statistical Journal, 2013
A common measure of tail dependence is the so-called tail-dependence coefficient. We present a nonparametric estimator of the tail-dependence coefficient and prove its strong consistency and asymptotic normality in the case of known marginal ...
Marta Ferreira
doaj   +1 more source

Rab14 regulates the transport of human papillomavirus to the trans‐Golgi network for infectious cell entry

open access: yesFEBS Letters, EarlyView.
This study reveals that the small GTPase Rab14 is necessary for human papillomavirus (HPV) infection and plays an essential role in the transport of virions to the trans‐Golgi network (TGN). HPV in the early endosome (EE), which harbors GTP‐bound Rab14, is transported to the TGN through the switch of Rab14 from its GTP‐bound to GDP‐bound form.
Yoshiyuki Ishii, Iwao Kukimoto
wiley   +1 more source

An M-estimator of multivariate tail dependence. [PDF]

open access: yes
AN M-ESTIMATOR OF TAIL DEPENDENCE. Extreme value theory is the part of probability and statistics that provides the theoretical background for modeling events that almost never happen.
Krajina, A.
core  

A copula-based nonparametric measure of regression dependence [PDF]

open access: yes, 2010
This paper presents a framework for comparing bivariate distributions according to their degree of regression dependence. We introduce the general concept of a regression dependence order (RDO).
Siburg, Karl Friedrich   +2 more
core   +1 more source

Informeasure: an R/bioconductor package for quantifying nonlinear dependence between variables in biological networks from an information theory perspective

open access: yesBMC Bioinformatics
Background Using information measures to infer biological regulatory networks can capture nonlinear relationships between variables. However, it is computationally challenging, and there is a lack of convenient tools.
Chu Pan, Yanlin Chen
doaj   +1 more source

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

open access: yesFEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto   +3 more
wiley   +1 more source

Mutual information: a universal measure of statistical dependence

open access: yes, 2014
A deluge of data is transforming science and industry. Many hope that this massive flux of information will reveal new vistas of insight and understanding, but extracting knowledge from Big Data requires appropriate statistical tools. Often, very little
Kinney, J. B.
core  

Component importance based on dependence measures [PDF]

open access: yesMathematical Methods of Operations Research, 2017
We discuss the construction of component importance measures for binary coherent reliability systems from known stochastic dependence measures by measuring the dependence between system and component failures. We treat both the time-dependent case in which the system and its components are described by binary random variables at a fixed instant as well
openaire   +2 more sources

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