Results 221 to 230 of about 9,392,573 (389)

E2A selectively regulates TGF‐β–induced apoptosis in KRAS‐mutant non‐small cell lung cancer

Molecular Oncology, EarlyView.
Ability to induce apoptosis by TGF‐β is frequently lost in advanced lung adenocarcinoma despite intact TGF‐β signaling. We identify E2A as a mutant KRAS–dependent mediator of resistance to TGF‐β–induced apoptosis. TGF‐β induces E2A via SMAD3 in mutant KRAS cells, and E2A silencing restores apoptosis and enhances radiation response in cell lines ...
Sergei Chuikov, Shiva Krishna Katkam, Zhefan Wang, Venkateshwar G. Keshamouni   +3 more
wiley   +1 more source

How does self-control influences college students' smartphone dependence: The chain mediating effect of mental toughness and social adaptability. [PDF]

PLoS One
Shen Q, Li L, Li C.
europepmc   +1 more source

Harm reduction measures in a recreational gym user with anabolic androgenic steroid dependence: a case report in the context of current best clinical practice

Magnolini, Raphael, Bottoni, Sofia Laura, Hammer, Helena, Capraro, Joël, Bruggmann, Philip, Senn, Oliver   +5 more
openalex   +1 more source

CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

Molecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau, Lilian G. Zhai, Ryunosuke Hoshi, Zackary Rousseau, Abraam Zakhary, Yin Fang Wu, Rola M. Saleeb, Heyu Ni, Kelsie L. Thu   +8 more
wiley   +1 more source

Etiological Development of Alcohol Use and Dependence From Adolescence to Midlife in a Longitudinal Community Study of Twins. [PDF]

Alcohol Clin Exp Res (Hoboken)
Huizenga BA, Alexander JD, Krueger RF, McGue M, Wilson S, Zellers SM, Vrieze SI.   +6 more
europepmc   +1 more source

Nonsymmetric Dependence Measures: the Discrete Case [PDF]

, 2015
Hui Li
openalex   +1 more source

Equivalence and bifurcations of finite order stochastic processes [PDF]

This article presents an equivalence notion of finite order stochastic processes. Local dependence measures are defined in terms of joint and marginal densities. The dependence measures are classified topologically using level sets.
Wagener, F.O.O., Diks C.G.H.
core  

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

Molecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan, Veronika M Metzler, Simone de Brot, Corinne L Woodcock, Anna E Harris, Jennifer Lothion‐Roy, Emeli M Nilsson, Atara Ntekim, Michael S Toss, Jenny L Persson, Francesca Khani, Brian D Robinson, Lorraine J Gudas, Emad Rakha, David M Heery, Catrin S Rutland, Nigel P Mongan   +16 more
wiley   +1 more source

The Short Nicotine Dependence Index: A Simple and Versatile Self-Report Measure of Nicotine Dependence for General Populations. [PDF]

Nicotine Tob Res
Jackson SE, Tattan-Birch H, Stapleton J, Jarvis MJ.   +3 more
europepmc   +1 more source

On Measuring Internal Dependence in a Set of Random Variables [PDF]

, 1987
Robert A. Koyak
openalex   +1 more source