Results 181 to 190 of about 1,082,690 (294)

A Model of Demasking and Hydrolysis of Peptide Bonds During Tryptic Digestion of β-Casein and β-Lactoglobulin. [PDF]

Molecules
Vorob'ev MM.
europepmc   +1 more source

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

Molecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan, Veronika M Metzler, Simone de Brot, Corinne L Woodcock, Anna E Harris, Jennifer Lothion‐Roy, Emeli M Nilsson, Atara Ntekim, Michael S Toss, Jenny L Persson, Francesca Khani, Brian D Robinson, Lorraine J Gudas, Emad Rakha, David M Heery, Catrin S Rutland, Nigel P Mongan   +16 more
wiley   +1 more source

A Journey from Statistics and Probability to Risk Theory An interview with Ludger Rüschendorf

Dependence Modeling, 2015
Durante Fabrizio, Puccetti Giovanni, Scherer Matthias   +2 more
doaj   +1 more source

Study of a Flexible ZnO/MWCNTs Thin Film Sensor for Hydrogen Peroxide Vapor Detection by Impedance Spectroscopy. [PDF]

Nanotechnol Sci Appl
Shahnazaryan G, Sayunts A, Shahkhatuni G, Papovyan R, Simonyan Z, Gevorgyan G, Grigoryan A, Kopecký D, Aleksanyan M.   +8 more
europepmc   +1 more source

Cell‐cycle‐specific lesion evolution rather than inhibition of double‐strand‐break repair underpins cisplatin radiosensitization

Molecular Oncology, EarlyView.
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu, Xixi Lin, Emil Mladenov, Veronika Mladenova, Jürgen Thomale, Ali Sak, Yao Wang, Yunxuan Deng, Eleni Gkika, Martin Stuschke, George Iliakis   +10 more
wiley   +1 more source

On the shape of the radiation survival curve in tumor spheroids: The role of oxygen heterogeneity. [PDF]

Med Phys
Schneider U, Liang N, Besserer J.
europepmc   +1 more source

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

Molecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

Stat Trek. An interview with Christian Genest

Dependence Modeling, 2016
Durante Fabrizio, Puccetti Giovanni, Scherer Matthias, Vanduffel Steven   +3 more
doaj   +1 more source

Investigation of the Gelation Process of a Polymer Composition Based on an Acrylic Polymer. [PDF]

Gels
Raupov I, Nosenko T, Grigoreva V, Zazulya V, Sukhoroslov G, Shkodkin V.   +5 more
europepmc   +1 more source

NKCC1: A key regulator of glioblastoma progression

Molecular Oncology, EarlyView.
Glioblastoma (GBM) progression is driven by disrupted chloride cotransporter homeostasis. NKCC1 is highly expressed in stem‐like, astrocytic, and progenitor cells, correlating with earlier recurrence, while overall survival remains unaffected. NKCC1 serves as a prognostic marker and potential therapeutic target, linking chloride transporter imbalance ...
Anja Thomsen, Diana Freitag, Madlen Haase, Christian Senft, Falko Schwarz, Silke Keiner   +5 more
wiley   +1 more source