Results 111 to 120 of about 670,645 (305)
Degradation mechanism of the von Willebrand factor A2 domain by nattokinase
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto +3 more
wiley +1 more source
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace +6 more
wiley +1 more source
rERA: An optimization algorithm of task dependency graph for scheduling [PDF]
In this paper, based on the analysis of task dependency, we propose an algorithm to remove the redundantedges of the task dependency graphs. The effectivenessof the algorithm is illustrated through a simpleexample.
Cheng, Zhuo, Tan, Yasuo, Lim, Yuto
core
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley +1 more source
LA LEY CATALANA DE SERVICIOS SOCIALES: ¿NUEVOS DERECHOS DE CIUDADANÍA EN EL ESTADO AUTONÓMICO? [PDF]
Law 12/2007, of 11 October, establishes the new framework for social servicesin Catalonia and tends towards universalization of the system with the intentionof moving beyond a vision based merely on assistance.
Vicenç Aguado i Cudolà
doaj
From mice to humans—divergent strategies for intestinal homeostasis and regeneration
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa +2 more
wiley +1 more source
Existence dependency: conceptual modelling by contract. [PDF]
In Object Orientation, the Generalisation/Specialisation hierarchy and the Whole/Part relationship are prevalent classification schemes for object types.
Dedene, Guido, Snoeck, Monique
core
Changes in Serum Biochemical Factors Associated with Opium Addiction after Addiction Desertion [PDF]
Introduction: The long time use of opium has some effects on serums biochemical factors, the determination of this variation is a new approach in understanding off addiction and relive of drug abuser health.
Mohammad Reza Afarinesh +5 more
doaj
Dependency-dependent Bounds for Sums of Dependent Random Variables
We consider the problem of bounding large deviations for non-i.i.d. random variables that are allowed to have arbitrary dependencies. Previous works typically assumed a specific dependence structure, namely the existence of independent components. Bounds that depend on the degree of dependence between the observations have only been studied in the ...
Lampert, Christoph H. +2 more
openaire +2 more sources
Phosphoinositides and inositol phosphates as molecular glues
Inositol phosphates (IPs) and phosphoinositides (PIPs) regulate diverse eukaryotic processes. Beyond recruiting signaling proteins or acting as structural cofactors, recent studies suggest they mediate protein–protein interactions as natural molecular glues.
Aleshia Seaton‐Terry +9 more
wiley +1 more source

