Results 51 to 60 of about 670,645 (305)

Infant Embryonal CNS Tumors: Molecular Insights and Treatment Considerations for Contemporary Pediatric Neuro‐Oncology

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background Embryonal tumors comprise the majority of malignant central nervous system (CNS) neoplasms diagnosed in children under 3 years of age. Compared with their counterparts in older children, these tumors exhibit distinct molecular biology and a more aggressive clinical phenotype, while their management is complicated by the heightened ...
Sudarshawn Damodharan   +3 more
wiley   +1 more source

The Potential Role of Iceland in Northern Europe’s Protein Self-Sufficiency: Feasibility Study of Large-Scale Production of Spirulina in a Novel Energy-Food System

open access: yesFoods, 2022
Europe is dependent on protein-rich crop imports to meet domestic food demand. This has moved the topic of sustainable protein self-sufficiency up the policy agenda.
Asaf Tzachor   +5 more
doaj   +1 more source

Ewing Sarcoma in Infants and Children Under 2 Years of Age: A French Retrospective Study

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Ewing sarcoma, the second most common primary bone cancer in children, requires intensive treatment that may lead to significant long‐term sequelae, particularly in infants. We retrospectively analyzed data from 1621 French patients treated between 1988 and 2015 within the EW88/93/97 or EE99 trials, focusing on 17 infants diagnosed before 24 ...
Elodie Verdier   +18 more
wiley   +1 more source

Provider and Parent Perspectives on Prioritizing the “Asking and Monitoring” Pediatric Cancer Psychosocial Standards of Care

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background The Standards for Psychosocial Care for Children with Cancer and Their Families (“Standards”) are evidence‐based guidelines for psychosocial care in pediatric oncology. Care related to the three “Asking and Monitoring” Standards—Assessment of Psychosocial Needs, Assessment of Financial Needs, and Monitoring Neurocognitive Problems ...
Julia B. Tager   +8 more
wiley   +1 more source

Lymphocyte homing disorder: a concealed driver of intestinal immune collapse in sepsis

open access: yesFrontiers in Immunology
Sepsis is defined as life-threatening organ dysfunction caused by a dysregulated host response to infection. “Lymphocyte homing”—the targeted migration of lymphocytes between organs—serves as the physiological foundation for immune surveillance and local
Huixian Geng   +7 more
doaj   +1 more source

Chemosensitivity depends on the dependency [PDF]

open access: yesJournal of Cell Biology, 2009
Two different anti-apoptotic proteins support cancer cell survival via an identical mechanism, yet differ in their sensitivity to chemotherapeutic drugs, report [Brunelle et al.][1] Cancer cells often become dependent on one or more anti-apoptotic proteins to avoid death while continuing ...
openaire   +1 more source

A Dependent Dependency Calculus (Extended Version)

open access: yesCoRR, 2022
Over twenty years ago, Abadi et al. established the Dependency Core Calculus (DCC) as a general purpose framework for analyzing dependency in typed programming languages. Since then, dependency analysis has shown many practical benefits to language design: its results can help users and compilers enforce security constraints, eliminate dead code, among
Pritam Choudhury   +2 more
openaire   +2 more sources

Survival After Hematopoietic Stem Cell Transplantation in Diamond–Blackfan Anemia Syndrome: The Role of Iron Overload—A Systematic Review

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT We assessed the effect of iron overload (IO) on mortality and complications following hematopoietic stem cell transplantation (HSCT) in patients with Diamond–Blackfan anemia syndrome (DBAS) in a systematic review of individual participant data and cohort data from observational studies.
Geoffrey Z. L. Kuppens   +6 more
wiley   +1 more source

The DCU dependency-based metric in WMT-MetricsMATR 2010 [PDF]

open access: yes, 2010
We describe DCU’s LFG dependencybased metric submitted to the shared evaluation task of WMT-MetricsMATR 2010. The metric is built on the LFG F-structurebased approach presented in (Owczarzak et al., 2007).
He, Yifan   +3 more
core   +3 more sources

A Situational Assessment of the Diagnostic Landscape and Organizational Readiness to Implement Next‐Generation Sequencing at Two Childhood Cancer Treatment Centers in Ghana

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Purpose Next‐generation sequencing (NGS) has emerged as a promising approach to improve diagnostic accuracy, but its feasibility in low‐ and middle‐income countries remains unknown. This study characterized the diagnostic landscape and assessed organizational readiness for NGS implementation at two childhood cancer treatment centers in Accra ...
Melissa Carvalho   +6 more
wiley   +1 more source

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