Molecular Oncology, EarlyView.Taxanes are widely used chemotherapeutics whose effects on cellular mechanics remain poorly understood. We show that paclitaxel induces rapid cellular contraction by promoting GEF‐H1 dissociation from microtubules and non‐muscle myosin II activation through RhoA/ROCK.
Gloria Asensio‐Juárez +5 more
wiley +1 more source
Association between perceived usefulness of generative AI for learning and generative AI dependency among university students in Changde, China: a cross-sectional study of statistical indirect effects. [PDF]
Front PsycholLiu Y, Liu Y.
europepmc +1 more source
Molecular Oncology, EarlyView.This study identifies ARHGAP5, in addition to the frequently mutated ARHGAP35, as significantly mutated in endometrial cancer. Mutations in both genes co‐occur and are associated with their correlated downregulation. Functional CRISPR studies show that both paralogs regulate similar pathways, including actin cytoskeleton organization.
Mathilde Pinault +12 more
wiley +1 more source
Modeling Memory Effects in a Head-Final Language With Category Locality. [PDF]
Open Mind (Camb)Isono S, Kajikawa K, Oseki Y, Asahara M.
europepmc +1 more source
Molecular Oncology, EarlyView.Incomplete microwave ablation (iMWA) of liver cancer triggers a biphasic progression in residual tumors. At Day 3, the microenvironment is characterized by acute inflammatory responses and extracellular matrix (ECM) remodeling. By Day 14, a profound shift occurs toward oncogenic signal transduction and immunosuppression, marked by macrophage ...
Yu Liu +9 more
wiley +1 more source
Character strengths, psychological distress, anxiety, and depression in adolescents and young adults with gynecologic cancer: A network analysis. [PDF]
Asia Pac J Oncol NursQin N +10 more
europepmc +1 more source
Molecular Oncology, EarlyView.Circulating microRNA profiles distinguish nonmalignant Lynch syndrome from cancer‐associated Lynch syndrome, sporadic colorectal cancer, and healthy controls. Age‐stratified analysis reveals disease‐specific regulatory states, and a six‐miRNA panel shows concordant separation in an independent colorectal tissue cohort.
Ramadhani Salum Chambuso +5 more
wiley +1 more source
Emotional Dependency and Parasocial Grief Following the Alteration or Loss of Companion Artificial Intelligences: A Systematic Review. [PDF]
Behav Sci (Basel)Ponce JLA +4 more
europepmc +1 more source
Molecular Oncology, EarlyView.The kinase SRPK1 directly interacts with the protein TOPBP1 and regulates the pre‐mRNA splicing of WIZ thereby contributing to the activation of the ATR/CHK1 replicative checkpoint in response to replicative stress. This allows cancer cells' genomic stability and survival.
Amani Shreim +17 more
wiley +1 more source
Status Threat or Grateful Reciprocity? Investigating Pathways Through Which Receiving Task-Related Help Influences Recipients' Subsequent Differentiated Helping Behavior. [PDF]
Behav Sci (Basel)Wu H, Chen J, Si B, Xia L, Mao Y.
europepmc +1 more source