Results 101 to 110 of about 29,845,221 (313)
Diversity and complexity in neural organoids
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source
Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz +11 more
wiley +1 more source
An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa +3 more
wiley +1 more source
Nonlinear modal regression for dependent data with application for predicting COVID-19. [PDF]
Ullah A, Wang T, Yao W.
europepmc +1 more source
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley +1 more source
Data for: A new temperature-dependent strategy to modulate the epidermal growth factor receptor
This dataset contains the DNA constructs of EGFR-ELPs and raw/processed data support the temperature-dependent activation and internalization of EGFR ...
MacKay, J +2 more
core +1 more source
RandomForestsGLS: An R package for Random Forests for dependent data. [PDF]
Saha A, Basu S, Datta A.
europepmc +1 more source
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure +3 more
wiley +1 more source
Parks and Gardens Data Service
Parks and Gardens UK is the leading on-line resource for historic parks and gardens providing freely accessible, accurate and inspiring information on UK parks, gardens and designed landscapes and all activities concerned with their promotion ...
Parks and Gardens Data Service
core +1 more source
Time-dependent Stokes equations with measure data
We establish the existence of a unique solution of an initial boundary value problem for the nonstationary Stokes equations in a bounded fixed cylindrical domain with measure data.
Bui An Ton
doaj +1 more source

