Results 241 to 250 of about 296,360 (329)

Aging as a Loss of Goal‐Directedness: An Evolutionary Simulation and Analysis Unifying Regeneration with Anatomical Rejuvenation

Advanced Science, EarlyView.
The paper proposes that the root cause of aging is the loss of anatomical goal‐directedness after development. Using evolutionary neural cellular automata simulations, the authors show that after the organism has reached its developmental homeostatic setpoint (the adult morphology), the absence of target state to pursue leads to a drifting anatomical ...
Léo Pio‐Lopez, Benedikt Hartl, Michael Levin   +2 more
wiley   +1 more source

Raised intracranial pressure alters cortical vascular function and cephalic allodynia. [PDF]

Brain
Grech O, Rubio-Beltran E, Stanyer EC, Labastida-Ramirez A, Lavery GG, Hill LJ, Holland PR, Sinclair AJ.   +7 more
europepmc   +1 more source

Wearable and Implantable Devices for Continuous Monitoring of Muscle Physiological Activity: A Review

Advanced Science, EarlyView.
Recent advances in materials and device engineering enable continuous, real‐time monitoring of muscle activity via wearable and implantable systems. This review critically summarizes emerging technologies for tracking electrophysiological, biomechanical, and oxygenation signals, outlines fundamental principles, and highlights key challenges and ...
Zhengwei Liao, Ata Golparvar, Mohammad Javad Bathaei, Filipe Arroyo Cardoso, Clementine M. Boutry   +4 more
wiley   +1 more source

Hallmark features of conventional BCS superconductivity in 2H-TaS₂. [PDF]

Sci Rep
Elson F, Kenji Forslund O, Palm R, Alshemi A, Abdel-Hafiez M, Simutis G, Shiroka T, Das D, Blackburn E, Weissenrieder J, Sassa Y, Månsson M.   +11 more
europepmc   +1 more source

Interfacial Coordination‐Engineered Emulgel Modulates the Osteo‐Immune Microenvironment in Periodontitis Treatment Via HIF1 Signaling Pathway‐Induced Metabolic Reprogramming

Advanced Science, EarlyView.
Schematic illustration of HIPPE‐QU‐mediated periodontal regeneration. a) Fabrication process and microstructure of HIPPE‐QU. b) Antimicrobial and immunomodulatory HIPPE‐QU hydrogel for periodontal regeneration. HIPPE‐QU hydrogel co‐delivers HA‐Cu, GNPs, and QU, providing antimicrobial effects and reprogramming the immune microenvironment to promote ...
Hui Zhang, Xiao Huang, Rui Chen, Weimin Lin, Linke Li, Xi Peng, Xinxi Yang, Xingyu Chen, Tailin Guo, Jie Weng, Jianshu Li, Quan Yuan, Huan Tan, Mengyuan Wang   +13 more
wiley   +1 more source

Leukemic Cells Hijack Stromal Bioelectricity to Reprogram the Bone Marrow Niche via CaV1.2-Dependent Mechanisms. [PDF]

Adv Sci (Weinh)
Da Ros A, Benetton M, Borella G, Longo G, Borile G, Cani A, Lopez-Pigozzi D, Bortolozzi M, Bresolin S, Tregnago C, Locatelli F, Pigazzi M.   +11 more
europepmc   +1 more source

Spatially Resolved Mapping of Voltage‐Gated Proton Channel Activity Reveals Delayed Proton Transport in Local Microenvironments

Advanced Science, EarlyView.
A revolutionary imaging platform integrating quantitative single‐molecule photobleaching with ratiometric fluorescence probes enables high‐throughput (≈2300 individually resolvable channels) mapping of individual proton channels in a large field (≈3000 µm2), overcoming the spatial and temporal limitations of conventional electrophysiology.
Jiahua Zhuang, Yang Xu, Yuxian Lu, Shiyang Lyu, Jie Tan, Jiandong Feng   +5 more
wiley   +1 more source

Bisphenol A Treatment Impairs Synaptic Function in Human Cholinergic Neurons. [PDF]

J Biochem Mol Toxicol
Carrese AM, Vitale R, Turco M, Aniello F, Petecca N, Cigliano L, Vitale E, Donizetti A.   +7 more
europepmc   +1 more source

Order–Disorder Phase Stabilization by Pressure‐Induced Charge Transfer Enhances the Ferroelectric Photovoltaic Effect in Multiferroic BaFe4O7

Advanced Science, EarlyView.
A pressure‐driven charge transfer in multiferroic BaFe4O7 induces Fe valence disproportionation and structural distortion, drastically narrowing the bandgap and enhancing ferroelectric polarization. This synergistic optimization boosts photocurrent 2.5‐fold and is retained upon decompression, offering a promising strategy to overcome the ferroelectric ...
Jiayi Guan, Bihan Wang, Nana Li, Shang Peng, Ganghua Zhang, Limin Yan, Xuqiang Liu, Kai Zhang, Mingtao Li, Adama N‐Diaye, Qingyu Kong, Dongzhou Zhang, Xu Zhao, Ting Liu, Kejun Bu, Yuhong Mao, Gui Wang, Xujie Lü, Xiang Li, Tao Zeng, Wenge Yang   +20 more
wiley   +1 more source