Results 271 to 280 of about 302,258 (333)

Traceless Regulation of Genetic Circuitry

Advanced Science, EarlyView.
Energy‐based, as opposed to molecular, control offers unprecedented improvements in key circuit parameters. This review summarizes the fundamentals of such traceless switches, categorizes them by trigger modalities, and compares and contrasts distinct advantages as well as shortcomings of each kind.
Gokberk Unal, Martin Fussenegger
wiley   +1 more source

Quercetin as a Bitter Taste Receptor Agonist with Anticancer Effects in Head and Neck Cancer Cells. [PDF]

Nutrients
Turner G, Sywanycz SM, Buchler BL, Wardlow RD, Lee RJ, Carey RM.   +5 more
europepmc   +1 more source

Amelioration of Post‐Stroke Edema and Microcirculatory Dysfunction via Targeted AQP4 Inhibition While Preserving the Glymphatic System

Advanced Science, EarlyView.
Compared to untargeted therapy, the targeted nanocarrier, Angiopep‐2‐conjugated Lipid Nanoparticle (A‐LNP) loaded with TGN‐020 (TGN), selectively accumulated in stroke‐injured regions. It suppressed local aquaporin‐4 (AQP4) overexpression, thereby alleviating cerebral edema and hypoperfusion while preserving global glymphatic clearance.
Lei Jin, Zeyu Yang, Boyang Wei, Yu Wu, Longxiang Li, Jiaming Zhou, Xin Zhang, Fa Jin, Shixing Su, Yanchao Liu, Ran Li, Shenquan Guo, Xingwu Liu, Yu Cai, Hong Liu, Min Chen, Wenchao Liu, Chuanzhi Duan, Xifeng Li   +18 more
wiley   +1 more source

Polarization, Depolarization

CORROSION ENGINEERING, 1980
openaire   +2 more sources

Wide Band Gap Boron Nitride Nanodots‐Incorporated Polyetherimide Dielectrics for High‐Temperature Dielectric Energy Storage

Advanced Science, EarlyView.
The inherent conjugation effects between molecular chains in PEI dielectrics induce substantial energy loss escalation at elevated temperatures. This study incorporated BNNDs into PEI films, successfully achieving effective capture of motion charges under high‐temperature conditions.
Wen‐jin Hu, Wen‐hao Huang, Nan Zhang, De‐xiang Sun, Yong Wang, Jing‐hui Yang   +5 more
wiley   +1 more source

The adrenal gland and primary aldosteronism: anatomy, steroidogenesis, regulation, and genetic insights. [PDF]

Front Endocrinol (Lausanne)
Long KC, Azizan EA.
europepmc   +1 more source

STING Agonist‐Modified Tumor Targeting Photosensitizer Remodels Cancer‐Associated Fibroblasts to Potentiate Photoimmunotherapy in Pancreatic Cancer

Advanced Science, EarlyView.
This carrier‐free, esterase‐responsive nanoaggregate integrates a mitochondria‐targeting photosensitizer with a non‐nucleotide STING agonist to achieve localized photoactivation and immune reprogramming. ICyM2 remodels tumor stroma, induces potent immunogenic cell death, and triggers intratumoral STING activation, collectively revitalizing the ...
Yixuan Zhang, Shankun Yao, Yihan Zhao, Saisai Zhu, Wen Fang, Ranran Yu, Naiwen Shi, Ruixin Zhang, Yin Zhang, Jiawei Liang, Ziying Zhang, Shijin Xu, Ziwei Zhang, Jiajun Zhang, Yukun Li, Xiaoxuan Han, Yuncong Chen, Shu Zhang, Ying Lv   +18 more
wiley   +1 more source

From Plankton to Primates: How VSP Sequence Diversity Shapes Voltage Sensing. [PDF]

Int J Mol Sci
Leong LM, Kim Y, Baker BJ.
europepmc   +1 more source

Changes in ventricular depolarization and repolarization in the clinical follow-up of a patient with Brugada syndrome

, 2018
Marcelo V. Puga Bravo, Jesús A. Castro Hevia, Yisel Gallardo Medina   +2 more
openalex   +1 more source

Integration of Freestanding High‐k Oxide Membranes for 2D Ferroelectric Field‐Effect Transistors

Advanced Science, EarlyView.
This work introduces a defect‐tolerant integration strategy that enables freestanding BaTiO3 membranes to form low‐leakage top‐gate junctions with MoS2. The resulting FeFETs exhibit a record 0.22 V nm−1 memory window, ultrahigh‐k response, and near‐ideal subthreshold swings.
Zejing Guo, Xuyang Sha, Fang Xu, Guangyi Huang, Jinfeng Zhang, Yang Mou, Guorui Zhao, Jiaqi Liu, Qing Lan, Wenqing Song, Cheng Zhang, Hai Huang, Changlin Zheng, Lingfei Wang, Hangwen Guo, Jian Shen, Wu Shi   +16 more
wiley   +1 more source