Results 121 to 130 of about 181,440 (305)

Technoeconomic and sustainability analysis of batch and continuous crystallization for pharmaceutical manufacturing

AIChE Journal, Volume 72, Issue 7, July 2026.
Abstract In pharmaceutical industries, continuous manufacturing methods have already been well established to improve productivity and process intensification. However, to better understand the trade‐offs of continuous crystallizers over the existing batch production systems, a robust technoeconomic cost and sustainability analysis is necessary to ...
Jungsoo Rhim, Zoltan K. Nagy
wiley   +1 more source

Revisiting the microtubule based quantum models of mind: tubulin bound GTP cannot pump microtubule coherence or provide energy for alpha <-> beta computation in stable microtubules [PDF]

, 2003
The current paper investigates the biological models of stable brain microtubules as quantum or classical computers whose function is based on electron hopping associated with kinking of the tubulin dimer. Hameroff (1998a, 1998b, 2003a, 2003b), Tuszynski
Georgiev, Danko
core  

Microtubule length distributions in the presence of protein-induced severing

, 2010
Microtubules are highly regulated dynamic elements of the cytoskeleton of eukaryotic cells. One of the regulation mechanisms observed in living cells is the severing by the proteins katanin and spastin.
B. Alberts, Bela M. Mulder, L. Quarmby, Simon H. Tindemans   +3 more
core   +1 more source

Depolymerization and Nanoliposomal Encapsulation of Grape Seed Condensed Tannins: Physicochemical Characterization, Stability, In Vitro Release and Bioaccessibility

Antioxidants
Condensed tannins from grape seed residues show high antioxidant activity but low oral bioavailability because of their high degree of polymerization and covalent interactions with proteins.
Carolina F. Morales, Marcela Zamorano, Natalia Brossard, Andreas Rosenkranz, Fernando A. Osorio   +4 more
doaj   +1 more source

Adversarial Erasing Enhanced Multiple Instance Learning (siMILe): Discriminative Identification of Oligomeric Protein Structures in Single Molecule Localization Microscopy

Advanced Intelligent Systems, EarlyView.
Hallgrimson et al. introduce a machine learning algorithm, siMILe, that takes features of single‐molecule localization microscopy localization clusters (e.g., size and sphericity) and finds the clusters that are associated with certain cell conditions (such as differential protein expression or drug treatment).
Christian Hallgrimson, Y. Lydia Li, Claire A. Shou, Ben Cardoen, John Lim, Timothy H. Wong, Ismail M. Khater, Ivan Robert Nabi, Ghassan Hamarneh   +8 more
wiley   +1 more source

Stem cell–based therapies for type 1 diabetes: Progress in differentiation, clinical translation, and immune protection

Animal Models and Experimental Medicine, EarlyView.
Directed differentiation of pluripotent stem cells into functional pancreatic β cells have emerged as a promising strategy for the radical treatment of type 1 diabetes, with preclinical and early clinical evidence demonstrating reversal of hyperglycemia and insulin independence.
Zifan Li, Yu Kang, Yuyu Niu
wiley   +1 more source

Distribution of lifetimes of kinetochore-microtubule attachments: interplay of energy landscape, molecular motors and microtubule (de-)polymerization

, 2014
Before a cell divides into two daughter cells, chromosomes are replicated resulting in two sister chromosomes embracing each other. Each sister chromosome is bound to a separate proteinous structure, called kinetochore (kt), that captures the tip of a ...
Chowdhury, Debashish, Sharma, Ajeet K., Shtylla, Blerta   +2 more
core   +1 more source

Preparation of Nitrogen-Doped Carbon-Supported Co-V Catalyst for Catalystic Depolymerization of Lignin to Produce Monophenolic Compounds

能源环境保护
Lignin, a renewable biomass component, holds promise as a fossil fuel alternative through its depolymerization into monophenolic compounds for liquid fuel production.
Yuqiao MA, Xingwang LIU, Yong QIAN, Xinping OUYANG   +3 more
doaj   +1 more source

Effect of Pd/C Catalytic Extraction on the Hydrothermal Depolymerization Properties of Ethanol Organosolv Lignin (EOL) in Supercritical Ethanol

BioResources, 2023
This study investigated the effect of a Pd/C catalytic extraction process on the hydrothermal depolymerization product properties of ethanol organosolv lignin (EOL) in supercritical ethanol. Phenolic products were separated and analyzed by gel permeation
Yuran Zhou, Bin Wen, Bei Liu
doaj  

Effects of post-translational modifications catalysed by pollen transglutaminase on the functional properties of microtubules and actin filaments [PDF]

, 2009
TGases (transglutaminases) are a class of calcium-dependent enzymes that catalyse the interactions between acyl acceptor glutamyl residues and amine donors, potentially making crosslinks between proteins.
Bonner, PLR, Cai, G, Cresti, M, Del, Duca, Serafini-Fracassini, D   +4 more
core