Results 111 to 120 of about 462,800 (317)

Single‐cell DNA methylation profiling: Technologies, computation, and applications in precision oncology

open access: yesMolecular Oncology, EarlyView.
Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley   +1 more source

A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

open access: yesFEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei   +3 more
wiley   +1 more source

Banking regulation and deposit insurance: legal and comparative perspective.

open access: yes, 2008
PhDA major point of debate in most financial systems is the relevance, form and scope of regulatory intervention, particularly on the trade-off between the benefits and costs of regulation.
Olanipekun, Oladapo Olumide
core  

Analysing the significance of small conformational changes and low occupancy states in serial crystallographic data

open access: yesFEBS Open Bio, EarlyView.
This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill   +4 more
wiley   +1 more source

Deposit Insurance During EU Accession [PDF]

open access: yes
The paper presents a brief review of the systems of deposit insurance in accession countries, comparing their level of harmonization with the perspective of their EU integration.
Nikolay Nenovsky, Kalina Dimitrova
core  

Software Deposit: What Not To Deposit

open access: yes, 2018
A software deposit lodged within a digital repository can contain myriad content. But there is certain content that should not be included within a software deposit. Some of this content may be innocuous and only result in your deposit being more bloated than it otherwise needs to be. Some of this content may compromise your security. And, in the worst
openaire   +1 more source

YlmG1 is localized exclusively to the chloroplast envelope membrane and is involved in preprotein translocation in Arabidopsis thaliana

open access: yesFEBS Open Bio, EarlyView.
Cytosolically synthesized chloroplast preproteins are translocated across the outer and inner envelope membranes through translocons called TOC and TIC, respectively. In green algae and plants, the TIC core is composed of essential membrane proteins, Tic12, Tic20, and Tic214.
Mengyi Li, Xueyang Zhao, Masato Nakai
wiley   +1 more source

Reforming deposit insurance and FDICIA [PDF]

open access: yes
Current discussions about deposit insurance reform center on issues such as the size of insurance premiums, the size of the fund, and the size of the coverage limits-all issues that reflect a concern with how to allocate the losses arising from bank ...
Larry D. Wall, Robert A. Eisenbeis
core  

Large‐Scale Submarine Sediment Waves at Macauley Caldera Volcano: In Situ Evidence of High‐Flux, Syn‐Eruptive Submarine Transport

open access: yesGeochemistry, Geophysics, Geosystems
Two sediment cores were collected from a submarine sediment wave field on the flank of Macauley volcano. Combined with seismic reflection surveys and numerical modeling, we present an integrated model of the formation of large‐scale, eruption‐fed ...
Shannon E. Frey   +3 more
doaj   +1 more source

Investigating an Enhanced Contour Blasting Technique Considering Rock Mass Structural Properties

open access: yesApplied Sciences
When excavating tunnels and underground openings with the drill-and-blast method, minimizing excavation overbreak is vital, as it reduces the costs associated with excavation stability, mucking, and rock support.
Askar Imashev   +2 more
doaj   +1 more source

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