Results 51 to 60 of about 1,453,523 (291)

Nicotinamide N‐methyltransferase promotes drug resistance in lung cancer, as revealed by nascent proteomic profiling

open access: yesMolecular Oncology, EarlyView.
AZD9291 has shown promise in targeted cancer therapy but is limited by resistance. In this study, we employed metabolic labeling and LC–MS/MS to profile time‐resolved nascent protein perturbations, allowing dynamic tracking of drug‐responsive proteins. We demonstrated that increased NNMT expression is associated with drug resistance, highlighting NNMT ...
Zhanwu Hou   +5 more
wiley   +1 more source

Moral hazard in the banking sector of Republika Srpska

open access: yesActa Economica, 2016
Many previous crisis in the banking sector showed that moral hazard is often one of the main causes of such crises. Failure of two banks in Republika Srpska in a very short period of time gave rise to this study to determine whether in the banking sector
Горана Крунић
doaj   +1 more source

Characterizing the salivary RNA landscape to identify potential diagnostic, prognostic, and follow‐up biomarkers for breast cancer

open access: yesMolecular Oncology, EarlyView.
This study explores salivary RNA for breast cancer (BC) diagnosis, prognosis, and follow‐up. High‐throughput RNA sequencing identified distinct salivary RNA signatures, including novel transcripts, that differentiate BC from healthy controls, characterize histological and molecular subtypes, and indicate lymph node involvement.
Nicholas Rajan   +9 more
wiley   +1 more source

Open Access Mandates and the "Fair Dealing" Button [PDF]

open access: yes, 2010
We describe the "Fair Dealing Button," a feature designed for authors who have deposited their papers in an Open Access Institutional Repository but have deposited them as "Closed Access" (meaning only the metadata are visible and retrievable, not the ...
Carr, Leslie   +4 more
core   +1 more source

Bridging the gap: Multi‐stakeholder perspectives of molecular diagnostics in oncology

open access: yesMolecular Oncology, EarlyView.
Although molecular diagnostics is transforming cancer care, implementing novel technologies remains challenging. This study identifies unmet needs and technology requirements through a two‐step stakeholder involvement. Liquid biopsies for monitoring applications and predictive biomarker testing emerge as key unmet needs. Technology requirements vary by
Jorine Arnouts   +8 more
wiley   +1 more source

The concept of corporate governance in the Russian civil law

open access: yesУченые записки Казанского университета: Серия Гуманитарные науки, 2020
In this paper, the concept of governance in the Russian civil law, which is defined as one of the key concepts of the existing legal science, was considered.
A.A. Pavlov
doaj   +1 more source

Investigating the cell of origin and novel molecular targets in Merkel cell carcinoma: a historic misnomer

open access: yesMolecular Oncology, EarlyView.
This study indicates that Merkel cell carcinoma (MCC) does not originate from Merkel cells, and identifies gene, protein & cellular expression of immune‐linked and neuroendocrine markers in primary and metastatic Merkel cell carcinoma (MCC) tumor samples, linked to Merkel cell polyomavirus (MCPyV) status, with enrichment of B‐cell and other immune cell
Richie Jeremian   +10 more
wiley   +1 more source

YAP1::TFE3 mediates endothelial‐to‐mesenchymal plasticity in epithelioid hemangioendothelioma

open access: yesMolecular Oncology, EarlyView.
The YAP1::TFE3 fusion protein drives endothelial‐to‐mesenchymal transition (EndMT) plasticity, resulting in the loss of endothelial characteristics and gain of mesenchymal‐like properties, including resistance to anoikis, increased migratory capacity, and loss of contact growth inhibition in endothelial cells.
Ant Murphy   +9 more
wiley   +1 more source

In-situ sedimentary evidence of complex bottom currents at a modern deepwater seamount

open access: yesCommunications Earth & Environment
Interactions between deep-ocean currents and seafloor sediments create bedforms that are important for paleoenvironment reconstructions, resource exploration, and mapping ecosystems.
Shannon E. Frey   +3 more
doaj   +1 more source

Deposit deregulation [PDF]

open access: yes
Depository Institutions Deregulation and Monetary Control Act of 1980 ; Depository Institutions Deregulation Committee ; Bank ...
Jack Beebe
core  

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