Results 71 to 80 of about 1,726,979 (337)

CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau   +8 more
wiley   +1 more source

Deposit deregulation [PDF]

open access: yes
Depository Institutions Deregulation and Monetary Control Act of 1980 ; Depository Institutions Deregulation Committee ; Bank ...
Jack Beebe
core  

Dense deposit disease involving C3 and C4d Deposits

open access: yesIndian Journal of Nephrology, 2018
Dense deposit disease (DDD), earlier called Type II membranoproliferative glomerulonephritis is distinct disease having frequent relapses reaching end-stage kidney disease by 10-year in up to 50%-60% of cases and high recurrence rate in the allograft. The term DDD is derived from its distinctive ribbon-like osmiophilic deposits in the lamina densa of ...
Vankalakunti, M.   +6 more
openaire   +2 more sources

Interaction of HS1BP3 with cortactin modulates TKS5 localisation, cell secretion and cancer malignancy

open access: yesMolecular Oncology, EarlyView.
Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen   +9 more
wiley   +1 more source

Progress of in situ U-Th/He Isotopic Dating Technique and Its Application to Low Temperature Deposits

open access: yesYankuang ceshi, 2017
The traditional single-grain U-Th/He isotopic dating method a uses time-consuming acid dissolution, correction for α-ejection and more requirements on target minerals (euhedral, transparent, no cracks or inclusions).
FU Shan-ling, ZHAO Cheng-hai
doaj   +1 more source

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

open access: yesMolecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary   +1 more
wiley   +1 more source

Clinical performance of the urine‐based TERT promoter AbsoluteQ Digital PCR for non‐invasive detection of bladder cancer

open access: yesMolecular Oncology, EarlyView.
A urine‐based digital PCR assay targeting two hotspot TERT promoter variants detected bladder cancer with high sensitivity and no false positives in this case–control cohort. The streamlined AbsoluteQ workflow outperformed Sanger sequencing and supports non‐invasive molecular testing for bladder cancer detection.
Anna Nykel   +12 more
wiley   +1 more source

Neyshabour turquoise mine: the first Iron Oxide Cu-Au-U-LREE (IOCG) mineralized system in Iran

open access: yesJournal of Economic Geology, 2012
Neyshabour turquoise mine is located in northwest of Neyshabour, southern Quchan volcanic belt. Eocene andesite and dacite forming as lava and pyroclastic rocks cover most of the area.
Mohammad Hassan Karimpour   +3 more
doaj  

Geology, petrography, alteration, mineralization and petrogenesis of intrusive bodies in the Hamech prospect area, Southwest of Birjand

open access: yesJournal of Economic Geology, 2018
Introduction The Hamech prospect area is located in the eastern Iran, 85 kilometers southwest of Birjand. The study area coordinates between 58¬¬˚¬53΄¬00 ˝ to 59˚¬00΄¬00˝ latitude and 32˚¬22΄¬30 ˝ to 32˚¬26΄¬00˝ longitude.
Abbas Etemadi   +2 more
doaj   +1 more source

Higher Quality Exhaustible Resource Deposits Receiving Higher or Lower Resource Rents in a Simple Spatial Framework [PDF]

open access: yes
Kolstad.s (1994) model of intertemporal, competitive supply to a linear market from two distinct exhaustible resource deposits admits two di¤erent interior solutions .
John Hartwick
core  

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