Results 81 to 90 of about 1,726,979 (337)

Mycobacterial cell division arrest and smooth‐to‐rough envelope transition using CRISPRi‐mediated genetic repression systems

open access: yesFEBS Open Bio, EarlyView.
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point   +7 more
wiley   +1 more source

Understanding the relationship between pore size, surface charge density, and Cu2+ adsorption in mesoporous silica

open access: yesScientific Reports
This research delved into the influence of mesoporous silica’s surface charge density on the adsorption of Cu2+. The synthesis of mesoporous silica employed the hydrothermal method, with pore size controlled by varying the length of trimethylammonium ...
Yanhui Niu   +3 more
doaj   +1 more source

Housing Affordability: Local and National Perspectives

open access: yesInternational Journal of Population Data Science, 2018
This paper presents a new approach to measuring affordable homeownership. Future changes in the homeownership rate will depend on the ability of today’s renters to become homeowners.
Laurie Goodman, Wei Li, Jun Zhu
doaj   +1 more source

Deposit insurance, moral hazard and market monitoring [PDF]

open access: yes
The paper analyses the relationship between deposit insurance, debt-holder monitoring, and risk taking. In a stylised banking model we show that deposit insurance may reduce moral hazard, if deposit insurance credibly leaves out non-deposit creditors ...
Gropp, Reint, Vesala, Jukka
core  

Open Access Mandates and the "Fair Dealing" Button [PDF]

open access: yes, 2014
We describe the "Fair Dealing Button," a feature designed for authors who have deposited their papers in an Open Access Institutional Repository but have deposited them as "Closed Access" (meaning only the metadata are visible and retrievable, not the ...
Carr, Les   +4 more
core  

Software Deposit: Why Deposit Software

open access: yes, 2018
This work was funded by Jisc. The Software Sustainability Institute is supported by EPSRC grant EP/H043160/1 and EPSRC/BBSRC and ESRC grant EP/N006410/1.
openaire   +1 more source

dUTPase is essential in zebrafish development and possesses several single‐nucleotide variants with pronounced structural and functional consequences

open access: yesFEBS Open Bio, EarlyView.
dUTPases are involved in balancing the appropriate nucleotide pools. We showed that dUTPase is essential for normal development in zebrafish. The different zebrafish genomes contain several single‐nucleotide variations (SNPs) of the dut gene. One of the dUTPase variants displayed drastically lower protein stability and catalytic efficiency as compared ...
Viktória Perey‐Simon   +6 more
wiley   +1 more source

Russian banks´ private deposit interest rates and market discipline [PDF]

open access: yes
This paper examines the extent to which the observed diversity of private deposit interest rates in Russia is explained by bank financial indicators. We also test for whether the introduction of the bank deposit insurance scheme in 2005 affected deposit ...
Golovan, S.V.   +2 more
core  

Dihydroorotate dehydrogenase (DHODH) regulates trophoblast syncytialization through organelle stress–induced cellular senescence

open access: yesFEBS Open Bio, EarlyView.
The inhibition of mitochondrial dihydroorotate dehydrogenase (DHODH) impairs syncytialization and induces cellular senescence via mitochondrial and endoplasmic reticulum stress in human trophoblast stem cells, elevating sFlt1/PlGF levels, a hallmark of placental dysfunction in hypertensive disorders of pregnancy.
Kanoko Yoshida   +6 more
wiley   +1 more source

Machine-learning crystal size distribution for volcanic stratigraphy correlation

open access: yesScientific Reports
Volcanic stratigraphy reconstruction is traditionally based on qualitative facies analysis complemented by geochemical analyses. Here we present a novel technique based on machine learning identification of crystal size distribution to quantitatively ...
Martin Jutzeler   +4 more
doaj   +1 more source

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