Results 241 to 250 of about 511,438 (311)

Identification of histone deacetylase inhibitor targeting type I interferon and B‐cell abnormalities in systemic lupus erythematosus

open access: yesArthritis &Rheumatology, Accepted Article.
Objective Systemic lupus erythematosus (SLE) is characterized by increased type I interferon (IFN‐I) and autoantibody production. This study aimed to identify drugs that can inhibit both IFN‐I and autoantibody production. Methods We identified an inhibitor of IFN‐I production from a chemical library.
Takehiro Hirayama   +16 more
wiley   +1 more source

Risk factors for relapse in ANCA‐associated vasculitis among patients with relapse after induction of remission with rituximab

open access: yesArthritis &Rheumatology, Accepted Article.
Objective To determine risk factors for relapse of ANCA‐associated vasculitis (AAV) after re‐induction of remission with rituximab and discontinuation of maintenance therapy. Methods This is a post‐hoc analysis of the RITAZAREM clinical trial. Patients 15 years or older with AAV and a positive test for anti‐proteinase‐3 (PR3‐) or anti‐myeloperoxidase ...
Ellen Romich   +10 more
wiley   +1 more source

“A lot of it is about feel”: The promise of sensory ethnography for anatomical education research

open access: yesAnatomical Sciences Education, EarlyView.
Abstract Ethnographers have constructed rich accounts of cultural settings since the early nineteenth century. A new approach, sensory ethnography, holds great promise for Health Professions Education scholars in its incorporation of the senses, particularly regarding anatomical teaching and learning. In this article, we describe sensory ethnography as
Paula Cameron, Olga Kits, Anna MacLeod
wiley   +1 more source

Production of 3D printed biomodels of the canine brain for veterinary neuroanatomy teaching

open access: yesAnatomical Sciences Education, EarlyView.
Abstract Teaching neuroanatomy presents multiple challenges to both students and teachers, as it is a subject with highly dense content that commonly causes the development of aversion by students, a phenomenon referred to as “neurophobia,” which has been documented in human and veterinary medicine students.
João Victor Barbosa Tenório Fireman   +1 more
wiley   +1 more source

A prudent planetary limit for geologic carbon storage. [PDF]

open access: yesNature
Gidden MJ   +10 more
europepmc   +1 more source

“Basic human things”: Investigating vehicle residents' continually fractured (information) landscapes

open access: yesJournal of the Association for Information Science and Technology, EarlyView.
Abstract This ethnographic study explores vehicle residents' information practices in the United States (US). Vehicle residents are people whose primary means of housing is a vehicle. This work builds on previous research encompassing transitions and fractured (information) landscapes. Using fractured information landscapes as the theoretical framework,
Kaitlin E. Montague
wiley   +1 more source

From cramming to binge‐watching: Integrating documentary‐based assessment into a pharmacology and toxicology curriculum—a qualitative study

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Abstract Aims In the context of pharmacology and toxicology education, there is a growing shift toward programmatic assessment models that prioritize longitudinal learning, reflection and development of higher‐order cognitive skills. As part of this transition, we are exploring alternative and more meaningful forms of assessment. This qualitative study
Narin Akrawi   +2 more
wiley   +1 more source

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