Results 31 to 40 of about 295,234 (265)
Wishbone pattern of iron accumulation: A pathognomonic sign of type III GM1 gangliosidosis
Annals of Movement Disorders, 2019 Type III GM1 gangliosidosis is the adult or chronic variant of a lysosomal storage disorder, which occurs secondary to deficiency of β-galactosidase.
Shweta Prasad +3 more
doaj +1 more source
Pattern of Residual Stress Formation at Gas-Thermal Coating Deposition
Наука и техника, 2003 The paper shows that gas-thermal coatings on the product surface may be considered on a first approximation as bimetallic material. Such approach permits to make calculations and determine residual stresses on the basis of multi-layer plate theory ...
A. F. Ilyuschenko +4 more
doaj +1 more source
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Riverbed erosion-deposition dynamics and driving mechanisms in Shenzhen Bay, 2002—2020
Shui kexue jinzhanUnderstanding erosion-deposition dynamics in coastal bays is crucial for the sustainable development and management of urban estuaries. This study investigates the interannual erosion–deposition dynamics in Shenzhen Bay from 2002 to 2020.
Yuantai KANG +3 more
doaj +1 more source
Iron deposition in Parkinson’s disease by quantitative susceptibility mapping
BMC Neuroscience, 2019 Background Patients with Parkinson’s disease (PD) have elevated levels of brain iron, especially in the nigrostriatal dopaminergic system. The purpose of this study was to evaluate the iron deposition in the substantia nigra (SN) and other deep gray ...
Qiqi Chen +7 more
doaj +1 more source
Patterned deposition at moving contact lines [PDF]
Advances in Colloid and Interface Science, 2014 When a simple or complex liquid recedes from a smooth solid substrate it often leaves a homogeneous or structured deposit behind. In the case of a receding non-volatile pure liquid the deposit might be a liquid film or an arrangement of droplets depending on the receding speed of the meniscus and the wetting properties of the system.
openaire +3 more sources
FEBS Letters, EarlyView.Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil +4 more
wiley +1 more source
Particle and Fibre Toxicology, 2023 Background The understanding of inhaled particle respiratory tract deposition is a key link to understand the health effects of particles or the efficiency for medical drug delivery via the lung.
Jenny Rissler +5 more
doaj +1 more source
FEBS Letters, EarlyView.Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai +4 more
wiley +1 more source
Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations
FEBS Letters, EarlyView.The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas +6 more
wiley +1 more source