Results 51 to 60 of about 295,234 (265)

Fabrication and evaluation of controllable deposition distance for aligned pattern by multi-nozzle near-field electrospinning

AIP Advances, 2018
To mass-volume fabricate micro- and nano-scales aligned pattern, multi-nozzle near-field electrospinning (NFES) direct-writing technology is well proposed as a high-efficiency method in electrohydrodynamic (EHD) printing process.
Zhifeng Wang, Xindu Chen, Jiarong Zhang, Ya-Ju Lin, Kuan Li, Jun Zeng, Peixuan Wu, Yunbo He, Yang Li, Han Wang   +9 more
doaj   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Experimental Study on the Process of the Hyperconcentrated Flood of the Tributaries’ Merging into the Upper Yellow River and the Deposition Pattern in the Confluence

工程科学与技术, 2013
:The process of the hyperconcentrated flow of tributaries merges into the upper Yellow River as well as the deposition pattern in confluence was preliminarily studied through experiment.
王平, 张原锋, 侯素珍, 胡恬, 吴保生   +4 more
doaj  

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

Molecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary, Jose Javier Bravo‐Cordero   +1 more
wiley   +1 more source

Controllable deposition distance of aligned pattern via dual-nozzle near-field electrospinning

AIP Advances, 2017
For large area micro/nano pattern printing, multi-nozzle electrohydrodynamic (EHD) printing setup is an efficient method to boost productivity in near-field electrospinning (NFES) process.
Zhifeng Wang, Xindu Chen, Jun Zeng, Feng Liang, Peixuan Wu, Han Wang   +5 more
doaj   +1 more source

MITF maintains genome stability in nonmelanocyte lineages

Molecular Oncology, EarlyView.
MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir, Adrián López García de Lomana, Thejus B. Venkatesh, Kritika Kirty, Snaevar Sigurdsson, Linda Vidarsdottir, Ramile Dilshat, Erla Sveinbjornsdottir, Snaedis Ragnarsdottir, Daniel H Magnusson, Maria R. Bustos, Eirikur Steingrimsson, Thorkell Gudjonsson, Stefan Sigurdsson   +13 more
wiley   +1 more source

Tumor B‐cell infiltration in platinum‐treated advanced muscle‐invasive urothelial carcinoma

Molecular Oncology, EarlyView.
Bladder tumors with higher pretreatment memory B‐cell infiltration were linked to longer survival after cisplatin chemotherapy, but not carboplatin. These tumors also showed more organized immune structures (tertiary lymphoid structures) and a shared pro‐inflammatory B‐cell‐rich community, suggesting that memory B cells may help identify patients most ...
Konrad Stawiski, Júlia Perera‐Bel, Alejo Rodriguez‐Vida, Nuria Juanpere, Jihyun Lee, Daniel E. Michaud, Jennifer L. Guerriero, Kent W. Mouw, Aristotelis Bamias, Filipe L. F. Carvalho, Joaquim Bellmunt   +10 more
wiley   +1 more source

Epigenetic heterogeneity and plasticity in therapy‐induced tumor states through single‐cell multi‐omics

Molecular Oncology, EarlyView.
Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim, Hwiyeong Lee, Jin Hong, Daechan Park   +3 more
wiley   +1 more source

PAK1 activation drives divergent resistance mechanisms to aromatase inhibition and tamoxifen in a luminal: A breast cancer model

Molecular Oncology, EarlyView.
Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller, Janina Müller, Efstathios‐Iason Vlachavas, Lukas Beumers, Lena Fleischhacker, Sara Burmester, Angelika Wörner, Sabine Karolus, Dominic Helm, Cindy Körner, Stefan Wiemann   +10 more
wiley   +1 more source

Associations between NIH Toolbox Cognition Battery and in vivo brain amyloid and tau pathology in non‐demented older adults

Alzheimer’s & Dementia: Diagnosis, Assessment & Disease Monitoring, 2020
Introduction The National Institutes of Health (NIH) Toolbox Cognition Battery (NIHTB‐CB) was developed to be a common assessment metric across a broad array of research studies.
Beth E. Snitz, Dana L. Tudorascu, Zheming Yu, Elizabeth Campbell, Brian J. Lopresti, Charles M. Laymon, Davneet S. Minhas, Neelesh K. Nadkarni, Howard J. Aizenstein, William E. Klunk, Sandra Weintraub, Richard C. Gershon, Ann D. Cohen   +12 more
doaj   +1 more source