Results 51 to 60 of about 10,071,563 (340)

Exploring the Pattern Associated With Longitudinal Changes of β-Amyloid Deposition During Cognitively Normal Healthy Aging

Frontiers in Medicine, 2021
The aim of this study was to determine a pattern associated with longitudinal changes of β-amyloid (Aβ) deposition during cognitively normal(CN) healthy aging.
Yunyan Xie, Qin Yang, Chunhua Liu, Qi Zhang, Jiehui Jiang, Jiehui Jiang, Jiehui Jiang, Ying Han, Ying Han, Ying Han, The Alzheimer's Disease Neuroimaging Initiative   +10 more
doaj   +1 more source

Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis

FEBS Letters, EarlyView.
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee, Junho Jeong, Chae Yeong Lee, Hyunjoon Cho, Man Hwan Oh, Je Chul Lee, Jee‐Young Lee, Yangmee Kim   +7 more
wiley   +1 more source

Pattern of Residual Stress Formation at Gas-Thermal Coating Deposition

Наука и техника, 2003
The paper shows that gas-thermal coatings on the product surface may be considered on a first approximation as bimetallic material. Such approach permits to make calculations and determine residual stresses on the basis of multi-layer plate theory ...
A. F. Ilyuschenko, S. S. Makarevich, Zh. A. Mrochek, L. M. Kozhuro, M. F. Pashkevich   +4 more
doaj   +1 more source

ABL kinase‐dependent phosphorylation of SH proteins promotes their direct interaction with CRK family SH2 domains

FEBS Letters, EarlyView.
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens, Brendan W. Chandler, Anna M. Schmoker, Jaye L. Weinert, Charlotte A. Kearns, Warren T. Yacawych, Amila Šemić, Alicia M. Ebert, Bryan A. Ballif   +8 more
wiley   +1 more source

National Atmospheric Deposition Program 2010 Annual summary [PDF]

, 2009
At the NADP Fall 2010 Meeting and Scientific Symposium, the NADP voted to approve the Ammonia Monitoring Network (AMoN) as the fifth NADP network.
National Atmospheric Deposition Program
core  

Iron deposition in Parkinson’s disease by quantitative susceptibility mapping

BMC Neuroscience, 2019
Background Patients with Parkinson’s disease (PD) have elevated levels of brain iron, especially in the nigrostriatal dopaminergic system. The purpose of this study was to evaluate the iron deposition in the substantia nigra (SN) and other deep gray ...
Qiqi Chen, Yiting Chen, Yue Zhang, Furu Wang, Hongchang Yu, Caiyuan Zhang, Zhen Jiang, Weifeng Luo   +7 more
doaj   +1 more source

Decoding the dynamic extracellular matrix in cancer—3D models and bioscaffolds rewire the rules of tumor progression

FEBS Letters, EarlyView.
Cancer progression is regulated by the dynamic matrix code of the tumor microenvironment, which influences cellular behavior and disease development. Importantly, matrix remodeling in three‐dimensional cancer models more accurately reflects in vivo conditions compared to conventional two‐dimensional systems.
Sylvia Mangani, Konstantinos Spanopoulos, Zoi Piperigkou, Nikos K. Karamanos   +3 more
wiley   +1 more source

Distinctive patterns of callose deposition provide an early sign of ovule abortion in the andromonoecious shrubCaesalpinia gilliesi

Boletín de la Sociedad Argentina de Botánica, 2009
Ovule abortion may lead to the partial or complete reduction of the number of functional ovules in the ovary and then is the primary factor that determines the sexual expression of the plant.
A. Calviño, C. Carrizo García
doaj   +1 more source

Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions

FEBS Letters, EarlyView.
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang, Hyo Been Jin, Chang Min Kim, So Yeon Lee, Hyun Ho Park   +4 more
wiley   +1 more source

An experimental study on lung deposition of inhaled 2 μm particles in relation to lung characteristics and deposition models

Particle and Fibre Toxicology, 2023
Background The understanding of inhaled particle respiratory tract deposition is a key link to understand the health effects of particles or the efficiency for medical drug delivery via the lung.
Jenny Rissler, Madeleine Peterson Sjögren, Julia Linell, Amalia Larsson Hurtig, Per Wollmer, Jakob Löndahl   +5 more
doaj   +1 more source