Results 61 to 70 of about 10,071,563 (340)

Deposition efficiency of inhaled particles (15-5000 nm) related to breathing pattern and lung function: an experimental study in healthy children and adults

Particle and Fibre Toxicology, 2017
Exposure to airborne particles has a major impact on global health. The probability of these particles to deposit in the respiratory tract during breathing is essential for their toxic effects.
J. Rissler, A. Gudmundsson, H. Nicklasson, E. Swietlicki, P. Wollmer, J. Löndahl   +5 more
semanticscholar   +1 more source

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

FEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta, Hari Baskar Balasubramanian, Amir Pasokh, Marietta Zille   +3 more
wiley   +1 more source

Influence of deposition path strategy on residual stress and deformation in weaving wire-arc additive manufacturing of disc parts

Journal of Materials Research and Technology
Deposition pattern and path-planning deposition strategy have significant impacts on the deformation and residual stress of components during a wire-arc additive manufacturing (WAAM) process. This work comparatively addressed the influence of weaving and
Jiang Zhao, Guo-zheng Quan, Yu-qing Zhang, Yao-yao Ma, Li-he Jiang, Wei-wei Dai, Qian Jiang   +6 more
doaj   +1 more source

Deposition pattern of inhaled radon progeny size distribution in human lung

, 2014
One of the important factors controlling the distribution of radiation dose to the different portions of the human respiratory tract is the deposition pattern of radon progeny containing aerosol.
A. Mohamed, M. Abd El-hady, M. Moustafa, M. Yuness   +3 more
semanticscholar   +1 more source

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

FEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang, Ruslana Romaniuk, Hristo L. Svilenov   +2 more
wiley   +1 more source

A Finite Element Study of Wire Arc Additive Manufacturing of Aluminum Alloy

Applied Sciences
Analyses in the present work focus on understanding the influence of the WAAM (wire arc additive manufacturing) deposition pattern and travel speed on residual stress and warpage in aluminum alloy. The thermal profiles are analyzed using thermomechanical
Yousung Han
doaj   +1 more source

Epigenetic reprogramming of lineage switching in cancer

FEBS Letters, EarlyView.
Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı, Burcu Akman, Ezgi Bağırsakçı, Nese Atabey, Serap Erkek‐Ozhan   +4 more
wiley   +1 more source

Weathering, atmospheric deposition and vegetation uptake: role for ecosystem sensitivity to acid deposition and critical load [PDF]

, 2004
Critical loads of acidity represent the maximum acceptable atmospheric deposition for an ecosystem type. Two hundred and forty-one ecosystem types have been defined in France using pedologic, geologic and vegetation data.
Anne Probst, Jean-Paul Party, Probst, Anne, Moncoulon, David, Party, Jean-Paul, David Moncoulon   +5 more
core   +1 more source

Embroidery Transfer Pattern

, 1940
Envelope for a McCall Kaumagraph Transfer pattern to embroider floral designs on suggested items such as sheets, pillowcases, infant wear, bibs, and lingerie; includes illustrations and information about stamping and embroidering the ...
McCall Pattern Company
core   +1 more source

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

FEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee, Mingming Tong, Anna L. Gloyn   +2 more
wiley   +1 more source