Results 81 to 90 of about 313,425 (309)

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

Molecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary, Jose Javier Bravo‐Cordero   +1 more
wiley   +1 more source

Investigation of charged aerosol transport and deposition in human airway models

, 2005
This thesis was submitted for the degree of Doctor of Philosophy and awarded by Brunel University.Several theoretical and experimental studies of charged aerosol deposition in human airways have been reported.
Koolpiruck, Diew
core  

Debris-flow erosion and deposition dynamics [PDF]

, 2011
Debris flows are a major natural hazard in mountains world wide, because of their destructive potential. Prediction of occurrence, magnitude and travel distance is still a scientific challenge, and thus research into the mechanics of debris flows is ...
SCHÜRCH, PETER
core  

Combinatory electric-field-guided deposition for spatial microparticles patterning

Materials Today Bio
Spatial deposition and patterning of microparticles are crucial in chemistry, medicine, and biology. Existing technologies like electric force manipulation, despite precise trajectory control, struggle with complex and personalized patterns.
Zhiyuan Zheng, Yang Zhang, Jinyu Xing, Xin Li, Zhiqiang Zhu, Min Ye, Shuwei Shen, Ronald X. Xu   +7 more
doaj   +1 more source

C5b9 Deposition in Glomerular Capillaries Is Associated With Poor Kidney Allograft Survival in Antibody-Mediated Rejection

Frontiers in Immunology, 2019
C4d deposition in peritubular capillaries (PTC) reflects complement activation in antibody-mediated rejection (ABMR) of kidney allograft. However, its association with allograft survival is controversial. We hypothesized that capillary deposition of C5b9—
Valentin Goutaudier, Hélène Perrochia, Simon Mucha, Marie Bonnet, Sylvie Delmas, Florian Garo, Valérie Garrigue, Sébastien Lepreux, Vincent Pernin, Vincent Pernin, Jean-Emmanuel Serre, Ilan Szwarc, Pierre Merville, Pierre Merville, Annie Ramounau-Pigot, Céline René, Jonathan Visentin, Jonathan Visentin, Bryan Paul Morgan, Véronique Frémeaux-Bacchi, Georges Mourad, Lionel Couzi, Lionel Couzi, Moglie Le Quintrec, Moglie Le Quintrec   +24 more
doaj   +1 more source

MITF maintains genome stability in nonmelanocyte lineages

Molecular Oncology, EarlyView.
MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir, Adrián López García de Lomana, Thejus B. Venkatesh, Kritika Kirty, Snaevar Sigurdsson, Linda Vidarsdottir, Ramile Dilshat, Erla Sveinbjornsdottir, Snaedis Ragnarsdottir, Daniel H Magnusson, Maria R. Bustos, Eirikur Steingrimsson, Thorkell Gudjonsson, Stefan Sigurdsson   +13 more
wiley   +1 more source

Accounting for the black carbon aging process in a two-way coupled meteorology–air quality model [PDF]

Atmospheric Chemistry and Physics
Black carbon (BC) exerts significant impacts on both climate and environment. The BC aging process alters its hygroscopicity and light absorption properties.
Y. Jin, Y. Jin, J. Wang, J. Wang, C. Liu, C. Liu, D. C. Wong, D. C. Wong, G. Sarwar, K. M. Fahey, S. Wu, S. Wu, J. Wang, J. Wang, J. Cai, J. Cai, J. Cai, Z. Tian, Z. Tian, Z. Zhang, Z. Zhang, J. Xing, A. Ding, A. Ding, S. Wang, S. Wang   +25 more
doaj   +1 more source

Tumor B‐cell infiltration in platinum‐treated advanced muscle‐invasive urothelial carcinoma

Molecular Oncology, EarlyView.
Bladder tumors with higher pretreatment memory B‐cell infiltration were linked to longer survival after cisplatin chemotherapy, but not carboplatin. These tumors also showed more organized immune structures (tertiary lymphoid structures) and a shared pro‐inflammatory B‐cell‐rich community, suggesting that memory B cells may help identify patients most ...
Konrad Stawiski, Júlia Perera‐Bel, Alejo Rodriguez‐Vida, Nuria Juanpere, Jihyun Lee, Daniel E. Michaud, Jennifer L. Guerriero, Kent W. Mouw, Aristotelis Bamias, Filipe L. F. Carvalho, Joaquim Bellmunt   +10 more
wiley   +1 more source

Epigenetic heterogeneity and plasticity in therapy‐induced tumor states through single‐cell multi‐omics

Molecular Oncology, EarlyView.
Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim, Hwiyeong Lee, Jin Hong, Daechan Park   +3 more
wiley   +1 more source

The plasmodesmal protein PDLP1 localises to haustoria-associated membranes during downy mildew infection and regulates callose deposition [PDF]

, 2014
The downy mildew pathogen Hyaloperonospora arabidopsidis (Hpa) is a filamentous oomycete that invades plant cells via sophisticated but poorly understood structures called haustoria.
Wirthmueller, Lennart, Jones, Jonathan D. G., Piquerez, Sophie J. M., Robatzek, Silke, Marie-Cécile Caillaud, Caillaud, Marie-Cécile, Jonathan D G Jones, Sklenar, Jan, Faulkner, Christine, Sophie J. M. Piquerez (198592), Kim Findlay (232058), Marie-Cécile Caillaud (3212142), Lennart Wirthmueller (646107), Silke Robatzek, Findlay, Kim, Jan Sklenar (142122), Jonathan D. G. Jones (198635), Jones, Alexandra M., Lennart Wirthmueller, Christine Faulkner, Alexandra M. E. Jones (50010), Silke Robatzek (242498), Kim Findlay, Alexandra M E Jones, Christine Faulkner (224195), Jan Sklenar, Sophie J M Piquerez   +26 more
core   +1 more source