Results 101 to 110 of about 10,071,563 (340)

MITF maintains genome stability in nonmelanocyte lineages

open access: yesMolecular Oncology, EarlyView.
MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir   +13 more
wiley   +1 more source

Textile Transfer Pattern

open access: yes, 1934
Envelope for a McCall Kaumagraph Transfer pattern to make appliqué tulip flower and flower pot designs for suggested items such as kitchen curtains, table runners and pot holders; includes illustrations of finished pieces and instructions for ...
McCall Pattern Company
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National Atmospheric Deposition Program 2003 Annual Summary [PDF]

open access: yes, 2003
is peer reviewedSubmitted by Susan Braxton (braxton@illinois.edu) on 2011-10-21T01:22:27Z No. of bitstreams: 1 2003as.pdf: 4347873 bytes, checksum: cee7d046da768ca5fc97c93f07b97012 (MD5)Made available in DSpace on 2011-10-21T01:22:27Z (GMT). No.
National Atmospheric Deposition Program
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C5b9 Deposition in Glomerular Capillaries Is Associated With Poor Kidney Allograft Survival in Antibody-Mediated Rejection

open access: yesFrontiers in Immunology, 2019
C4d deposition in peritubular capillaries (PTC) reflects complement activation in antibody-mediated rejection (ABMR) of kidney allograft. However, its association with allograft survival is controversial. We hypothesized that capillary deposition of C5b9—
Valentin Goutaudier   +24 more
doaj   +1 more source

PAK1 activation drives divergent resistance mechanisms to aromatase inhibition and tamoxifen in a luminal: A breast cancer model

open access: yesMolecular Oncology, EarlyView.
Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller   +10 more
wiley   +1 more source

Spatial and single‐nuclei transcriptomics reveals idiosyncratic and generic patterns in papillary and anaplastic thyroid cancers

open access: yesMolecular Oncology, EarlyView.
Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur   +11 more
wiley   +1 more source

Carefree Pattern

open access: yes, 1975
McCall's Carefree Pattern #4387 by Halston to make stretch knit cape with asymmetrical drape and flared skirt with waistband, including illustrations of the finished pieces and information about sizing and construction on the ...
Halston, 1932-1990   +1 more
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