Results 31 to 40 of about 14,281 (294)

Depositional facies, sequence stratigraphy and reservoir potential of the Eocene Nanka Formation of the Ameki Group in Agu-Awka and Umunya, southeast Nigeria

open access: yesHeliyon, 2021
A sedimentological investigation was carried out in Agu-Awka and Umunya localities to interpret the facies, depositional environment, sequence stratigraphy, reservoir potential, and architecture of the outcropping Eocene Nanka Formation of the Ameki ...
Ovie B. Ogbe, Jerry Osokpor
doaj   +1 more source

Microfacies and depositional environment of the Upper Oligocene and Lower Miocene successions from Iraqi Kurdistan Region

open access: yesKuwait Journal of Science, 2020
Upper Oligocene and Lower Miocene successions in the High/Low Folded Thrust Zones boundary from the Sulaimani District, Kurdistan region, northeast Iraq, are manifested and represented by Bajwan, Anah and Jeribe formations, which are consists mainly of ...
Fadhil Ahmed Ameen   +2 more
doaj  

Sequence Stratigraphic Interpretation of XY-Field Onshore Niger Delta Basin Nigeria

open access: yesJournal of Applied Sciences and Environmental Management, 2022
Wireline logs and biostratigraphic data were integrated to attempt the sequence stratigraphy of “XY field” onshore Niger Delta Basin which revealed three depositional sequences.
C.E. Okpala   +4 more
doaj   +1 more source

From omics to AI—mapping the pathogenic pathways in type 2 diabetes

open access: yesFEBS Letters, EarlyView.
Integrating multi‐omics data with AI‐based modelling (unsupervised and supervised machine learning) identify optimal patient clusters, informing AI‐driven accurate risk stratification. Digital twins simulate individual trajectories in real time, guiding precision medicine by matching patients to targeted therapies.
Siobhán O'Sullivan   +2 more
wiley   +1 more source

The nicotinamide hypothesis revisited—plant defense signaling integrating PARP, nicotinamide, nicotinic acid, epigenetics, and glutathione

open access: yesFEBS Letters, EarlyView.
Nicotinamide (NIC) and nicotinic acid (NIA) are proposed as stress signaling compounds in plants. Oxidative stress may lead to single strand breaks (SSB) in DNA, which activate poly(ADP‐ribose) polymerase (PARP). NIC and NIA are then formed from NAD. NIC and NIA can promote epigenetic changes leading to the expression of defense genes specific for the ...
Torkel Berglund, Anna B. Ohlsson
wiley   +1 more source

Imeglimin attenuates liver fibrosis by inhibiting vesicular ATP release from hepatic stellate cells

open access: yesFEBS Letters, EarlyView.
Imeglimin, at clinically relevant concentrations, inhibits vesicular ATP accumulation and release from hepatic stellate cells, thereby attenuating purinergic signaling and reducing fibrogenic activation. This mechanism reveals a newly identified antifibrotic action of imeglimin beyond glycemic control.
Seiji Nomura   +8 more
wiley   +1 more source

Depositional environment of shales and enrichment of organic matters of the Lower Cambrian Niutitang Formation in the Upper Yangtze Region

open access: yesNatural Gas Industry B, 2021
The Niutitang Formation in the Upper Yangtze Region comprises a set of the Early Cambrian black shales containing abundant organic matter. We investigated the relationship between the depositional environment and organic matter enrichment based on core ...
Xue Yang   +8 more
doaj   +1 more source

Biophysical analysis of angiotensin II and amyloid‐β cross‐interaction in aggregation and membrane disruption

open access: yesFEBS Letters, EarlyView.
Angiotensin II (AngII), a neuropeptide, interacts with amyloid‐β (Aβ), a key player in Alzheimer's disease. This study reveals that AngII reduces Aβ aggregation and membrane disruption in vitro. Biophysical assays and molecular modeling suggest AngII binds disordered Aβ forms, potentially modulating early amyloidogenic events and contributing to ...
Mohsen Habibnia   +5 more
wiley   +1 more source

Targeting EZH2 reverses thyroid cell dedifferentiation and enhances iodide uptake in anaplastic thyroid cancer

open access: yesFEBS Letters, EarlyView.
Anaplastic thyroid cancer (ATC) lacks iodide uptake ability due to MAPK activation increasing the expression of the histone methyltransferase EZH2, which represses thyroid differentiation genes (TDGs) such as the sodium iodide symporter (NIS). Dual inhibition of MAPK (U0126) and EZH2 (EPZ6438/Tazemetostat) reverses this mechanism, thus restoring TDG ...
Diego Claro de Mello   +6 more
wiley   +1 more source

The impact of depositional environment and tectonic evolution on coalbed methane occurrence in West Henan, China

open access: yesInternational Journal of Mining Science and Technology, 2019
A deeper understanding of the mechanisms by which geological factors (depositional environment and tectonic evolution) control the occurrence of coalbed methane (CBM) is important for the utilization of CBM resources via surface-drilled wells and the ...
Zhaodan Cao, Baiquan Lin, Ting Liu
doaj   +1 more source

Home - About - Disclaimer - Privacy