Results 31 to 40 of about 14,281 (294)
A sedimentological investigation was carried out in Agu-Awka and Umunya localities to interpret the facies, depositional environment, sequence stratigraphy, reservoir potential, and architecture of the outcropping Eocene Nanka Formation of the Ameki ...
Ovie B. Ogbe, Jerry Osokpor
doaj +1 more source
Upper Oligocene and Lower Miocene successions in the High/Low Folded Thrust Zones boundary from the Sulaimani District, Kurdistan region, northeast Iraq, are manifested and represented by Bajwan, Anah and Jeribe formations, which are consists mainly of ...
Fadhil Ahmed Ameen +2 more
doaj
Sequence Stratigraphic Interpretation of XY-Field Onshore Niger Delta Basin Nigeria
Wireline logs and biostratigraphic data were integrated to attempt the sequence stratigraphy of “XY field” onshore Niger Delta Basin which revealed three depositional sequences.
C.E. Okpala +4 more
doaj +1 more source
From omics to AI—mapping the pathogenic pathways in type 2 diabetes
Integrating multi‐omics data with AI‐based modelling (unsupervised and supervised machine learning) identify optimal patient clusters, informing AI‐driven accurate risk stratification. Digital twins simulate individual trajectories in real time, guiding precision medicine by matching patients to targeted therapies.
Siobhán O'Sullivan +2 more
wiley +1 more source
Nicotinamide (NIC) and nicotinic acid (NIA) are proposed as stress signaling compounds in plants. Oxidative stress may lead to single strand breaks (SSB) in DNA, which activate poly(ADP‐ribose) polymerase (PARP). NIC and NIA are then formed from NAD. NIC and NIA can promote epigenetic changes leading to the expression of defense genes specific for the ...
Torkel Berglund, Anna B. Ohlsson
wiley +1 more source
Imeglimin attenuates liver fibrosis by inhibiting vesicular ATP release from hepatic stellate cells
Imeglimin, at clinically relevant concentrations, inhibits vesicular ATP accumulation and release from hepatic stellate cells, thereby attenuating purinergic signaling and reducing fibrogenic activation. This mechanism reveals a newly identified antifibrotic action of imeglimin beyond glycemic control.
Seiji Nomura +8 more
wiley +1 more source
The Niutitang Formation in the Upper Yangtze Region comprises a set of the Early Cambrian black shales containing abundant organic matter. We investigated the relationship between the depositional environment and organic matter enrichment based on core ...
Xue Yang +8 more
doaj +1 more source
Angiotensin II (AngII), a neuropeptide, interacts with amyloid‐β (Aβ), a key player in Alzheimer's disease. This study reveals that AngII reduces Aβ aggregation and membrane disruption in vitro. Biophysical assays and molecular modeling suggest AngII binds disordered Aβ forms, potentially modulating early amyloidogenic events and contributing to ...
Mohsen Habibnia +5 more
wiley +1 more source
Anaplastic thyroid cancer (ATC) lacks iodide uptake ability due to MAPK activation increasing the expression of the histone methyltransferase EZH2, which represses thyroid differentiation genes (TDGs) such as the sodium iodide symporter (NIS). Dual inhibition of MAPK (U0126) and EZH2 (EPZ6438/Tazemetostat) reverses this mechanism, thus restoring TDG ...
Diego Claro de Mello +6 more
wiley +1 more source
A deeper understanding of the mechanisms by which geological factors (depositional environment and tectonic evolution) control the occurrence of coalbed methane (CBM) is important for the utilization of CBM resources via surface-drilled wells and the ...
Zhaodan Cao, Baiquan Lin, Ting Liu
doaj +1 more source

