Results 61 to 70 of about 8,044,550 (301)

Gerakan struktur dan kaitannya dengan faktor kendali tektonik, berdasarkan analisis stratigrafi; Studi kasus geologi kuarter terhadap fase perkembangan Danau Tondano purba sepanjang Remboken - Kakas, Kec. Remboken dan Kec. Kakas, Kab. Tomohon, Sulawesi Ut

Indonesian Journal on Geoscience, 2014
http://dx.doi.org/10.17014/ijog.vol2no3.20075Studies of stratigraphy on Quaternary deposits in the southwest region of Lake Tondano, Tomohon Regency, South Sulawesi, revealed six facies of deposition environments.
Herman Moechtar, Indyo Pratomo, Herman Mulyana, Soemantri Poedjoprajitno   +3 more
doaj   +1 more source

Protocol for quantifying miRNA trafficking across the endosomal membrane

FEBS Open Bio, EarlyView.
An in vitro protocol measures miRNA uptake into endosomes isolated from mammalian cell extracts, which are free of subcellular contaminants. Performed at 37 °C in the presence of ATP, it ensures the import of single‐stranded miRNA into the endosomal lumen.
Syamantak Ghosh, Kamalika Mukherjee, Suvendra N. Bhattacharyya   +2 more
wiley   +1 more source

GelMA‐based 3D spheroids recapitulate transcriptomic and functional hallmarks of myeloid sarcoma

FEBS Open Bio, EarlyView.
GelMA 5% hydrogels support the formation of myeloid leukemia spheroids that recapitulate MS‐specific features, including G1 arrest, apoptosis, and ECM‐driven transcriptomic reprogramming. The 3D model mimicked soft‐tissue‐like stiffness and oxygen conditions, and transcriptomic convergence with primary MS samples confirmed its utility as a preclinical ...
Nicolas Germain, Elise Buret, Le Hoang Thanh Nguyen, Marion Cocheteux, Nicolas Touya, Mélanie Dhayer, Romain Dubois, Frank Lafont, Sebastien Janel, Patrice Maboudou, Steve Lancel, Philippe Marchetti   +11 more
wiley   +1 more source

Chemical Characteristics of Macroscopic Pyrogenic Carbon Following Millennial-Scale Environmental Exposure

Frontiers in Environmental Science, 2020
Pyrogenic Carbon (PyC) is ubiquitous in global environments, and is now known to form a significant, and dynamic component of the global carbon cycle, with at least some forms of PyC persisting in their depositional environment for many millennia ...
Philippa L. Ascough, Fiona Brock, Margaret E. Collinson, Jon D. Painter, David W. Lane, Michael I. Bird, Michael I. Bird   +6 more
doaj   +1 more source

Mutant NPM1 in Acute Myeloid Leukemia Initiation and Maintenance

Aging and Cancer, EarlyView.
NPM1 mutations drive acute myeloid leukemia by acting as neomorphic transcriptional regulators that cooperate with Menin–MLL and XPO1 to sustain HOX/MEIS1 expression and block differentiation. Targeting these mutant‐specific transcriptional dependencies provides a rational therapeutic strategy for NPM1‐mutated AML.
Yanan Jiang, Zhong Fan, Runmeng Liu, Xiaotian Zhang   +3 more
wiley   +1 more source

Corrigendum: Sequence stratigraphy of the Middle Jurassic Yan’an formation (NE Ordos Basin, China), relationship with climate conditions and basin evolution, and coal maceral’s characteristics

Frontiers in Earth Science, 2023
Dawei Lv, Dawei Lv, Yangyang Shen, A. J. Tom van Loon, Munira Raji, Zhihui Zhang, Guangzeng Song, Zhouhe Ren, Yujia Wang, Dongdong Wang   +9 more
doaj   +1 more source

SPG4 and Dementia: Expanding the Clinical Spectrum

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Hereditary spastic paraplegia (HSP) is a group of disorders characterized by progressive spasticity and lower limb weakness, with mutations in SPG4/SPAST being the most common cause. Detailed studies and clinical and molecular comparisons across different populations are missing.
Emanuele Panza, Arun Meyyazhagan, Eliseo Picchi, Gustavo Ribas, Ingrid Faber, Ryosuke Miyamoto, Preethi Basavaraju, Paolo Eusebi, Haripriya Kuchi Bhotla, Mario Stasi, Fabrizio Gaudiello, Francesco Patti, Filippo Maria Santorelli, Marcondes Cavalcante França Jr, José Luiz Pedroso, Orlando Graziani Povoas Barsottini, Hélio Afonso Ghizoni Teive, Peter Henry St George‐Hyslop, Toshitaka Kawarai, Antonio Orlacchio   +19 more
wiley   +1 more source

Depositional Environment of the Late Miocene of Lemau Formation from Bengkulu Basin Based on Palynology in Seluma, Bengkulu, Indonesia

JGEET: Journal of Geoscience, Engineering, Environment and Technology
Indonesia has several sedimentary basins, one of which is the Bengkulu Basin. One of the rock formations that make up this basin is the Lemau Formation, which is of Middle-Late Miocene age.
Sakilla Gia Mentari, Winantris, Lia Jurnaliah, Novita Iwa Anjani   +3 more
doaj   +1 more source

T1 Over Squared Proton Density Ratio to Characterize Multiple Sclerosis Lesions

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Differentiating remyelinated from demyelinated lesions in MS remains challenging without histological confirmation. This study introduces the T1‐to‐PD2 ratio (TPR) imaging approach and evaluates its ability to characterize MS lesions alongside other quantitative MRI (qMRI) metrics. Methods Thirty individuals with MS (mean age: 47.5 ± 
Sarah J. Wright, Scotty G. McKay, Jean Ramos Bou, Fen Bao, Vivian B. Truong, Chenyang Li, Li Jiang, Anza B. Memon, E. Mark Haacke, Yulin Ge, Yongsheng Chen   +10 more
wiley   +1 more source

Artificial Intelligence in Systemic Sclerosis: Clinical Applications, Challenges, and Future Directions

Arthritis Care &Research, EarlyView.
Systemic sclerosis (SSc) is a rare autoimmune disease defined by immune dysregulation, vasculopathy, and progressive fibrosis of the skin and internal organs. Despite advances in care, major complications such as interstitial lung disease (ILD) and myocardial involvement remain the leading causes of morbidity and mortality.
Cristiana Sieiro Santos, José Miguel Sequí‐Sabater, Diego Benavent   +2 more
wiley   +1 more source