Results 41 to 50 of about 1,580,450 (269)

Bathymetric surveys and lake deposits [PDF]

open access: yes, 1938
A progress report on the bathymetric survey of Windereme undertaken in June 1937 by the Hydrographic Department of the Admiralty. The brief article outlines the background of the surveying process as well as the initial effectiveness of the survey work ...
Mortimer, C.H., Worthington, E.B.
core  

Conserved structural motifs in PAS, LOV, and CRY proteins regulate circadian rhythms and are therapeutic targets

open access: yesFEBS Letters, EarlyView.
Cryptochrome and PAS/LOV proteins play intricate roles in circadian clocks where they act as both sensors and mediators of protein–protein interactions. Their ubiquitous presence in signaling networks has positioned them as targets for small‐molecule therapeutics. This review provides a structural introduction to these protein families.
Eric D. Brinckman   +2 more
wiley   +1 more source

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

open access: yesFEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka   +11 more
wiley   +1 more source

Mixed ether bath for electrodeposition of aluminum [PDF]

open access: yes, 1969
Anisole added to the bath mixture improves Brenner aluminum plating bath technique. Mixture has lower bath vapor-pressure and the electro-deposits obtained have greater physical strength than deposits from the Brenner ...
Lui, K.
core   +1 more source

Cell wall target fragment discovery using a low‐cost, minimal fragment library

open access: yesFEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan   +5 more
wiley   +1 more source

Thermochemical oxidation of methane induced by high-valence metal oxides in a sedimentary basin

open access: yesNature Communications, 2018
The role of thermochemical oxidation of methane (TOM) by high-valence metal oxides as a potential methane sink remains poorly understood. Here, the authors present evidence of TOM induced by Mn(Fe) oxides in a sedimentary basin, which yields calcite with
Wen-Xuan Hu   +5 more
doaj   +1 more source

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

open access: yesFEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson   +7 more
wiley   +1 more source

SkyScan 1172 X-ray micro-CT scanner of well-core digital modeling for geophysical analysis of landscape polystructures

open access: yesGeology, Ecology, and Landscapes
The present study deals with algorithms for the acquisition of a well-core digital model that is used in the Digital Well-Core technology or “Digital Petrophysics.” The study involved the initial implementation stage of this technology: identification of
Marsel A. Kadyrov   +4 more
doaj   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

Intraluminal Deposits Found in Glaucoma Tube Shunts Via Anterior Segment Ocular Coherence Tomography [PDF]

open access: yes, 2018
PURPOSE: To describe and characterize a novel observation of intraluminal deposits of glaucoma tube shunts (TS) using spectral domain (SD) ocular coherence topography (OCT).
Alvarado, Jorge A.   +2 more
core   +1 more source

Home - About - Disclaimer - Privacy