Results 41 to 50 of about 1,600,082 (335)

‘They Need to Hear You Say It’: Healthcare Professionals’ Perspectives on Barriers and Enablers to End‐of‐Life Discussions With Adolescents and Young Adults With Cancer

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT End‐of‐life conversations with adolescents and young adults (AYAs) with cancer rarely occur without the guidance of healthcare professionals. As a part of the ‘Difficult Discussions’ study, focused on palliative care and advance care planning discussions with AYAs with cancer, we investigated the factors that healthcare professionals identify ...
Justine Lee   +9 more
wiley   +1 more source

Mapping the evolution of mitochondrial complex I through structural variation

open access: yesFEBS Letters, EarlyView.
Respiratory complex I (CI) is crucial for bioenergetic metabolism in many prokaryotes and eukaryotes. It is composed of a conserved set of core subunits and additional accessory subunits that vary depending on the organism. Here, we categorize CI subunits from available structures to map the evolution of CI across eukaryotes. Respiratory complex I (CI)
Dong‐Woo Shin   +2 more
wiley   +1 more source

TITANOMAGNETITE ORES: MINERAL COMPOSITION AND MÖSSBAUER SPECTROSCOPY [PDF]

open access: yesМинералогия, 2017
Chemical and mineral composition of ilmenite-titanomagnetite ores from Chiney, Sludinsky, Bystrinsky and Kruchininsky deposits (East Siberia) are studied and compared with those from the Panzhihua pluton in China using microprobe and X-ray diffraction ...
V.P. Lyutoev   +5 more
doaj  

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

open access: yesFEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka   +11 more
wiley   +1 more source

Software Deposit: Where To Deposit Software

open access: yes, 2018
This work was funded by Jisc. The Software Sustainability Institute is supported by EPSRC grant EP/H043160/1 and EPSRC/BBSRC and ESRC grant EP/N006410/1.
openaire   +3 more sources

Cell wall target fragment discovery using a low‐cost, minimal fragment library

open access: yesFEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan   +5 more
wiley   +1 more source

Behaviour of Rare Earth Elements in the resent Sediments of Water Plants tanks and of Domestic Water in Mosul City [PDF]

open access: yesKirkuk Journal of Science, 2017
The present study includes distribution of rare earth elements in the resent sediments of the water plants and in domestic water tanks in some areas in Mosul city.
Hazim Ameen Muhammad   +1 more
doaj   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

Structural biology of ferritin nanocages

open access: yesFEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

SkyScan 1172 X-ray micro-CT scanner of well-core digital modeling for geophysical analysis of landscape polystructures

open access: yesGeology, Ecology, and Landscapes
The present study deals with algorithms for the acquisition of a well-core digital model that is used in the Digital Well-Core technology or “Digital Petrophysics.” The study involved the initial implementation stage of this technology: identification of
Marsel A. Kadyrov   +4 more
doaj   +1 more source

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