Results 11 to 20 of about 374,365 (198)

Depot medroxyprogesterone acetate and breast cancer: a systematic review. [PDF]

Arch Gynecol Obstet, 2023
Abstract Purpose Short-acting progestin-only injectables containing depot medroxyprogesterone acetate (DMPA) are a safe method of contraception. Although DMPA has been available for several decades, there is little data on its influence on the risk of breast cancer. Hence, the aim of this paper was to provide an overview
Zürcher A, Knabben L, von Gernler M, Stute P.   +3 more
europepmc   +6 more sources

Depot medroxyprogesterone acetate (DMPA)-associated early-onset osteoporotic fracture [PDF]

Endocrinology, Diabetes & Metabolism Case Reports
Depot medroxyprogesterone acetate (DMPA) is a highly effective injectable contraceptive, but is associated with reduced bone mineral density (BMD) and increased fracture risk in some studies because it inhibits the hypothalamic–pituitary–ovarian axis ...
Yotsapon Thewjitcharoen, Veekij Veerasomboonsin, Soontaree Nakasatien, Thep Himathongkam   +3 more
doaj   +2 more sources

Meningioma regression following depot medroxyprogesterone acetate withdrawal: a case series [PDF]

BMJ Neurology Open
Background Progesterone signalling is a key determinant of meningioma behaviour, particularly in skull base tumours. Cyproterone acetate-associated meningiomas stabilise or regress after withdrawal Whether similar reversibility follows cessation of depot
Allan Taylor, Byron De John, Richard J. Burman, Vishesh Sood, David Le Feuvre, Darlene Lubbe   +5 more
doaj   +2 more sources

Contraception in adolescents with mental disorders: adherence and satisfaction in the use of depot medroxyprogesterone acetate [PDF]

Revista Brasileira de Ginecologia e Obstetrícia
Objective: To evaluate the continuation rate, satisfaction, and reasons for discontinuation of depot medroxyprogesterone acetate (DMPA) in adolescents treated in a mental health service.
Giani Silvana Schwengber Cezimbra, Edward Araujo Júnior, Cristina Aparecida Falbo Guazzelli   +2 more
doaj   +2 more sources

Multi-omics analysis of the cervical epithelial integrity of women using depot medroxyprogesterone acetate. [PDF]

PLoS Pathogens, 2022
Depot medroxyprogesterone acetate (DMPA) is an injectable hormonal contraceptive used by millions of women worldwide. However, experimental studies have associated DMPA use with genital epithelial barrier disruption and mucosal influx of human ...
Frideborg Bradley, Mathias Franzén Boger, Vilde Kaldhusdal, Alexandra Åhlberg, Gabriella Edfeldt, Julie Lajoie, Sofia Bergström, Kenneth Omollo, Anastasios Damdimopoulos, Paulo Czarnewski, Anna Månberg, Julius Oyugi, Joshua Kimani, Peter Nilsson, Keith Fowke, Annelie Tjernlund, Kristina Broliden   +16 more
doaj   +2 more sources

Depot Medroxyprogesterone Acetate and Risk of Meningioma in the US.

JAMA Neurol
Importance There lacks data clarifying the meningioma risk conferred by depot medroxyprogesterone acetate in the US. Objective To examine the relative risk of meningioma diagnosis in women using depot medroxyprogesterone acetate and ...
Xiao T, Kumar P, Lobbous M, Yogi-Morren D, Soni P, Recinos PF, Kshettry VR.   +6 more
europepmc   +4 more sources

Implementation strategies to scale up self-administered depot medroxyprogesterone acetate subcutaneous injectable contraception: a scoping review [PDF]

Systematic Reviews, 2023
Background Self-administered depot medroxyprogesterone acetate subcutaneous injectable contraception (DMPA-SC) is registered in many countries. It shows great potential for improving contraceptive access, continuation, and autonomy.
Adeniyi Kolade Aderoba, Petrus Schoken Steyn, James Njogu Kiarie   +2 more
doaj   +2 more sources

Vaginal Atrophy following Long-Term Depot Medroxyprogesterone Acetate Use: A Case Report

Case Reports in Obstetrics and Gynecology, 2013
Depot medroxyprogesterone acetate (DMPA) is a commonly used form of contraception, with noncontraceptive benefits for the user. The mode of action is through the suppression of ovulation. It leads to hypoestrogenism which causes dryness of the vagina and
Christie Walker, Shawky Z. A. Badawy
doaj   +2 more sources

Differential Effects of Depot Medroxyprogesterone Acetate Administration on Vaginal Microbiome in Hispanic White and Black Women

Emerging Microbes and Infections, 2019
The use of depot medroxyprogesterone acetate (DMPA), a 3-monthly injectable hormonal contraceptive, is associated with an increased risk of HIV acquisition possibly through alteration of the vaginal microbiome.
Zhiheng Pei, Dervla Kelly, Stuart M. Brown   +2 more
exaly   +3 more sources

Medroxyprogesterone Acetate Levels Among Kenyan Women Using Depot Medroxyprogesterone Acetate in the FEM-PrEP Trial [PDF]

Contraception, 2016
To describe medroxyprogesterone acetate (MPA) levels among Kenyan depot medroxyprogesterone acetate (DMPA) users in the FEM-PrEP HIV prevention trial, and to compare MPA levels between ARV for HIV prevention (treatment) and placebo groups.We measured MPA in previously collected plasma samples from 63 Kenyan trial participants who used DMPA for one or ...
Rebecca L Callahan, David Jenkins, Lut van Damme   +2 more
exaly   +3 more sources