Results 71 to 80 of about 374,365 (198)

RICTOR Prevents Decidualization Disorder in Women With Advanced Maternal Age via Regulating FoxO1 Nuclear Export

open access: yesAging Cell, Volume 25, Issue 9, September 2026.
Advanced maternal age impairs uterine decidualization via downregulated RICTOR‐ATK3‐FoxO1 signaling. The RICTOR agonist MHY1485 rescues decidual defects, offering a therapy for age‐related pregnancy failure. ABSTRACT Miscarriage and abnormal embryonic development in women of advanced maternal age (AMA) are often associated with impaired decidualization.
Yifeng Lin   +9 more
wiley   +1 more source

Patient satisfaction of depot medroxyprogesterone acetate (dmpa-sc) injection as contraceptive

open access: yes, 2010
Patient satisfaction of depot medroxyprogesterone acetate (dmpa-sc) injection as ...
M Afzal (13515244)   +2 more
core  

Hyperoside alleviates endometrial stromal cell senescence in unexplained recurrent spontaneous abortion via DHX9‐mediated R‐loop resolution

open access: yesiMeta, Volume 5, Issue 4, August 2026.
This study suggests that the food‐derived flavonoid hyperoside may act as a natural DExH‐box helicase 9 (DHX9) modulator, directly targeting Thr419 of DHX9 to help resolve pathological R‐loop accumulation. Consequently, it suppresses cyclic GMP‐AMP synthase‐stimulator of interferon genes (cGAS‐STING)‐driven endometrial stromal senescence and restores ...
Yuepeng Jiang   +18 more
wiley   +1 more source

Depot Medroxyprogesterone Acetate Contraceptive Injections and Skeletal Health

open access: yesWomen's Health, 2010
This editorial focuses on the effect that depot medroxyprogesterone acetate (DMPA) or Depo-Provera® has on skeletal health. It describes what happens to bone mineral density (BMD) during Depo-Provera® use as well as what happens after Depo-Provera® is discontinued. It also discusses the evidence behind this particular issue but states the importance of
Regina Maria, Renner   +2 more
openaire   +2 more sources

Physiological Basis of Sex Differences in Human Performance and Exercise‐Associated Pathology

open access: yesClinical Endocrinology, Volume 105, Issue 2, Page 151-162, August 2026.
ABSTRACT The presence of sex differences in human physical performance is well‐established and shaped by distinct endocrine, anatomical and physiological mechanisms. Despite sustained advances, our understanding of how inherent biological factors drive variations in exercise capacity and related pathologies is still developing.
David A. Holdsworth   +7 more
wiley   +1 more source

Successful treatment of Depot Medroxyprogesterone acetate-related vaginal bleeding improves continuation rates in Adolescents

open access: yesThe Scientific World Journal, 2006
High discontinuation rates for depot medroxyprogesterone acetate (DMPA) in adolescents may contribute to the number of unintended pregnancies. Many cite vaginal bleeding as a reason for discontinuing DMPA use.
Kristin M. Rager   +2 more
doaj   +1 more source

Counting the costs: Comparing depot medroxyprogesterone acetate and norethisterone oenanthate utilisation patterns in South Africa

open access: yesBMC Health Services Research, 2001
Background In South Africa, where health care resources are limited, it is important to ensure that drugs provision and use is rational. The Essential Drug List includes depot medroxyprogesterone acetate (DMPA) and norethisterone oenanthate (NET-EN) as ...
Gray Andrew   +3 more
doaj   +1 more source

Expectations and Experiences of Side Effects Among Adolescent Women Using Intramuscular and Subcutaneous Depot Medroxyprogesterone Acetate [PDF]

open access: yes, 2010
Background: Intramuscular depot medroxyprogesterone acetate (DMPA-IM) has known physical side effects including changes in bleeding. A lower dose, subcutaneous formulation (DMPA-SC) is available with a similar side effect profile among adult women ...
Tanner, Amanda Elizabeth   +1 more
core  

Depot Medroxyprogesterone Acetate (Depo-Provlera) as a Contrac·eptive Preparation [PDF]

open access: yes, 2017
Experience with depot medroxyprogesterone acetate as a contraceptive preparation in 7 335 patients for a total of 38 714 months over a 3-year period is described.
Bloch, Basil
core  

Management of secondary amenorrhea induced by injectable contraceptive through Ayurveda: A case report

open access: yesJournal of Ayurveda Case Reports
Secondary amenorrhea refers to the absence of regular menstrual periods for at least three menstrual cycles with previous regular cycles or for six months with irregular cycles.
Kamini Dhiman, V. Vijila
doaj   +1 more source

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