Results 31 to 40 of about 2,122 (263)

Selective elimination of quiescent cancer cells by dequalinium chloride via ROS‐mediated ferroptosis

FEBS Open Bio, EarlyView.
Dequalinium chloride (DQ) selectively eliminates quiescent cancer cells (QCCs) by amplifying mitochondrial ROS. QCCs exhibit elevated basal ROS and limited redox‐buffering capacity, making them vulnerable to further ROS increases. DQ‐induced ROS exceeds the tolerance threshold, triggering lipid peroxidation and ferroptosis, whereas proliferating cells ...
Kotaro Miyamoto, Shiori Sakai, Minori Endo, Terigele, Mizuho Niibori, Taiki Morita, Yu Goto, Arisa Yoshida, Tomohiro Tanaka, Ning Lin, Takahiro Kuchimaru, Hiroyuki Nakamura, Masahiro Inoue, Shinae Kizaka‐Kondoh, Tetsuya Kadonosono   +14 more
wiley   +1 more source

MOGAD Is the Most Common Cause of Isolated Optic Neuritis in Children

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives The study aimed to characterize the clinical features, etiologies, and outcomes of isolated, first‐time pediatric ON in the post‐MOG‐IgG era. Methods This was a single‐center retrospective cohort study at Texas Children's Hospital of patients diagnosed with first‐time ON between 2018–2024, with follow‐up data collected through 2025.
Chaitanya Aduru, Akansha Chandrasekar, Kyla Blasingame, Jonathan Rosen, Jesse M. Levine, Karla Salazar, Madhuri Chilakapati, Rod Foroozan, Victoria Hardwick, Jonathan M. Yarimi, Nikita Shukla, Timothy E. Lotze, Kristen S. Fisher, Alexander J. Sandweiss   +13 more
wiley   +1 more source

Night Lighting and Domestic Dogs Reduce Livestock Depredation Risk in the Tropical Lowlands of Nepal

Conservation Letters
Increasing livestock depredation by recovering large carnivore populations undermines local support for long‐term conservation. Past studies on livestock depredation have primarily focused on biophysical predictors, often overlooking the role of ...
Bijaya Neupane, Ambika P. Gautam, Dietrich Schmidt‐Vogt, Nicholas J. Hogarth, Edward L. Webb   +4 more
doaj   +1 more source

WILD TURKEY DEPREDATION OF COMMERCIALLY GROWN GRAPES

Wildlife Society Bulletin, 2015
: With successful restoration of wild turkeys (Meleagris gallopavo; hereafter, turkey) has come concerns among some agricultural producers about potential crop depredation.
Thomas W. Hughes, Robert E. Eriksen
doaj   +1 more source

Cognitive and Neuroimaging Divergence Between Juvenile and Adult FUS Amyotrophic Lateral Sclerosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disorder characterized by progressive motor neuron degeneration. Fused in sarcoma (FUS)‐associated juvenile ALS (jALS) represents a distinct and aggressive subgroup with rapid deterioration and poor prognosis.
Alexandra V. Jürs, Marcel Naumann, Annaliis Lehto, Hanna Schön, Jens Kurth, Johannes Prudlo, Andreas Hermann, Elisabeth Kasper   +7 more
wiley   +1 more source

Fisher–shark interactions: A loss of support for the Maldives shark sanctuary from reef fishers whose livelihoods are affected by shark depredation

Conservation Letters, 2022
Targets for protecting predatory species often fail to consider the human costs of conservation. Human–wildlife interactions can increase following conservation action and present a major ecological and socioeconomic challenge.
Danielle Robinson, Steven P. Newman, Mark J. Whittingham, Richard M. Francksen, M. Shiham Adam, Selina M. Stead   +5 more
doaj   +1 more source

Complex Human-Shark Conflicts Confound Conservation Action

Frontiers in Conservation Science, 2021
Human-wildlife conflicts are a growing phenomenon globally as human populations expand and wildlife interactions become more commonplace. While these conflicts have been well-defined in terrestrial systems, marine forms are less well-understood.
Colin A. Simpfendorfer, Michelle R. Heupel, Dave Kendal   +2 more
doaj   +1 more source

Global Rather Than Vertical‐Selective Saccadic Abnormalities in Progressive Supranuclear Palsy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To test whether vertical saccades are preferentially affected in Progressive Supranuclear Palsy (PSP). Methods PSP patients (n = 24) were compared to age‐matched controls (n = 94) and two degenerative groups (Alzheimer's disease, n = 20; Lewy body disease, n = 50).
Duy Duan Nguyen, Mark Paine, Soohyun Lee, Amir Fazlollahi, Baibin (Ben) Wang, John D. O'Sullivan, Peter J. Nestor   +6 more
wiley   +1 more source

REAL AND PERCEIVED DAMAGE BY WILD TURKEYS: A LITERATURE REVIEW

Wildlife Society Bulletin, 2015
: As populations of wild turkeys (Meleagris gallopavo; hereafter, turkeys) have increased, number of complaints about damage to agricultural crops and other resources has increased. To better understand this, we conducted a literature review to determine
Scott R. Groepper, Scott E. Hygnstrom, Brandon Houck, Stephen M. Vantassel   +3 more
doaj   +1 more source

Subsidized Fencing of Livestock as a Means of Increasing Tolerance for Wolves

Ecology and Society, 2011
Studies of how proactive measures to reduce livestock depredation by carnivores affect human tolerance toward carnivores are extremely rare. Nevertheless, substantial amounts of money are spent each year on proactive measures to facilitate large ...
Jens Karlsson, Magnus Sjöström
doaj   +1 more source