Effectiveness of a multidisciplinary team-delivered deprescribing intervention for patients with chronic kidney disease: a protocol for a randomised controlled trial [PDF]
Introduction Inappropriate polypharmacy is prevalent among patients with chronic kidney disease (CKD), and can be mitigated by deprescribing. We aim to evaluate the clinical and economic impact of a multidisciplinary deprescribing programme in Qatar’s ...
Amani Zidan +10 more
doaj +2 more sources
Background Cost, scalability, and durability represent major challenges to the implementation of intensive lifestyle treatments for obesity and diabetes.
Laura Buchanan +6 more
semanticscholar +4 more sources
Deprescribing Anticholinergic Medications in Hospitalised Older Adults: A Systematic Review. [PDF]
ABSTRACT Background Anticholinergic medication use is increasing, particularly among older adults due to polypharmacy and comorbidities. High anticholinergic burden is linked to adverse outcomes such as reduced mobility and increased dementia risk. Acute hospital stays may offer an opportunity to address this often‐overlooked issue. Aims To examine the
Griffiths R +5 more
europepmc +2 more sources
Insights Into Pharmacist-Led Deprescribing of Benzodiazepines and Related Drugs: A Qualitative Study With Physicians and Pharmacists. [PDF]
ABSTRACT While deprescribing benzodiazepines and related drugs (BZRDs) is crucial for preventing prolonged use and their associated adverse effects, it presents challenges from a healthcare perspective, because of limited resources and time. Recently, a pharmacist‐led deprescribing of BZRDs in the treatment of insomnia was introduced in Helsinki's ...
Korppas M +3 more
europepmc +2 more sources
Deprescribing Benzodiazepine Receptor Agonists in Older Adults and People With Cognitive Impairment: A Systematic Review. [PDF]
ABSTRACT Background Benzodiazepine receptor agonists (BZRAs) (benzodiazepines and z‐drugs) may provide limited benefits in the management of insomnia when used short‐term. However, they increase the risk of harms including falls, fractures, hospitalizations, and cognitive impairment. Deprescribing (cessation) of BZRAs may be beneficial for older adults
McEvoy AM +5 more
europepmc +2 more sources
Deprescription in Palliative Care
Individuals with limited life expectancy represent a significant proportion of healthcare consumers and are usually patients with multiple diseases and high levels of frailty. Polypharmacy and the prescription of long lists of drugs are frequent in patients with reduced life expectancy and often, as the patient's health status deteriorates, the list of
Cabrera, Joana A +3 more
openaire +2 more sources
Towards optimal use of antithrombotic therapy of people with cancer at the end of life: a research protocol for the development and implementation of the SERENITY shared decision support tool Thrombosis Research [PDF]
Background: Even though antithrombotic therapy has probably little or even negative effects on the well-being of people with cancer during their last year of life, deprescribing antithrombotic therapy at the end of life is rare in practice.
Abbel, D. +78 more
core +13 more sources
Background: Good prescribing practices form the essence of drug therapy for better patient care. The major aim of better prescribing is to improve rational prescribing. Deprescribing gained momentum in recent decades.
Narayan Gaurang +4 more
doaj +1 more source
Billing Deprescribing Interventions: Portrait of an Initiative in Québec, Canada. [PDF]
ABSTRACT Background Deprescribing is a patient‐centred process in which a healthcare professional reduces or stops medications to improve health outcomes. Since late 2022, community pharmacists in Québec, Canada, have been able to bill for deprescribing interventions, enabling more robust deprescribing research in large cohort studies.
Calfat AC, Gosselin M, Sirois C.
europepmc +2 more sources
Prescriptive Appropriateness: Inhospital Adherence to Proton Pump Inhibitors Deprescription Flow Chart. [PDF]
The prescriptive appropriateness of Proton Pump Inhibitors (PPIs) in polypharmacy is controversial. PPIs are often overprescribed and the risk of prescribing errors and adverse drug reactions increases for each additional drug added to therapy. Hence, guided deprescription should be considered and easily implementable in ward practice.
Baiardi G +7 more
europepmc +4 more sources

