Results 21 to 30 of about 69,933 (288)

Depression and Oral FTC/TDF Pre-exposure Prophylaxis (PrEP) Among Men and Transgender Women Who Have Sex With Men (MSM/TGW). [PDF]

, 2016
We conducted a longitudinal and cross-sectional analysis of depressive symptomology in iPrEx, a randomized, placebo-controlled trial of daily, oral FTC/TDF HIV pre-exposure prophylaxis (PrEP) in men and transgender women who have sex with men. Depression-
Amico, K Rivet, Avelino-Silva, Vivian I, Burns, David, Chodacki, Piotr, Defechereux, Patricia A, Fernandez, Telmo, Glidden, David V, Grant, Robert M, iPrEx Study Team, Liu, Albert Y, Mayer, Kenneth H, McMahan, Vanessa M, Mehrotra, Megha, Vargas, Lorena   +13 more
core   +1 more source

Effects of camphor and related compounds on slowly adapting mechanoreceptors in the rat sinus hair follicle

IBRO Neuroscience Reports, 2022
Introduction: Camphor is a popular compound for therapeutic and cosmetic use with a distinctive odour, and somatosensory warming and cooling properties. The mechanisms for its action remain unclear.
Peter M.B. Cahusac, Arunteja Veermalla
doaj   +1 more source

The Ethics of Placebo-controlled Trials: Methodological Justifications [PDF]

, 2013
The use of placebo controls in clinical trials remains controversial. Ethical analysis and international ethical guidance permit the use of placebo controls in randomized trials when scientifically indicated in four cases: (1) when there is no proven ...
Grady, Christine, Millum, Joseph
core   +1 more source

Anti-depressant medication use is a risk factor for incident knee surgery and opioid use in patients with knee osteoarthritis

Frontiers in Psychiatry, 2023
ObjectiveTo investigate whether depression and exposure to anti-depressant medication are independent risk factors for incident knee surgery and opioid use in knee osteoarthritis (KOA) patients.MethodsWe identified all patients who visited our outpatient
Yongqiang Zheng, Jinshan Zhang, Zefeng Wang, Xiaofeng Liu, Yongquan Xu, Yangzhen Fang, Zhenyu Lin, Liang Lin   +7 more
doaj   +1 more source

CNS anti-depressant, anxiolytic and analgesic effects of Ganoderma applanatum (mushroom) along with ligand-receptor binding screening provide new insights: Multi-disciplinary approaches

Biochemistry and Biophysics Reports, 2021
This research was designed to evaluate the CNS depressant, anxiolytic, and analgesic action of aqueous and ethanol extract of Ganoderma applanatum, a valuable medicinal fungus used in multiple disorders belongs to Ganodermataceae family.
S M Moazzem Hossen, Mohammad Jahedul Islam, Md. Rabiul Hossain, Anik Barua, Md. Giash Uddin, Nazim Uddin Emon   +5 more
doaj   +1 more source

Cardiovascular and cortisol reactions to acute psychological stress and cognitive ability in the Dutch Famine Birth Cohort Study [PDF]

, 2011
Objective: Recently, in analyses of data from a large community sample, negative cross-sectional and prospective associations between cardiac stress reactivity and obesity were observed.
al'Absi, al'Absi, al'Absi, Backs, Bakker, Balanos, Barnett, Blair, Busato, Carroll, Carroll, Carroll, Carroll, Carroll, Carroll, Carroll, Deary, DeGangi, deRooij, deRooij, deRooij, Domes, Duschek, Dweck, Elias, Elias, Everson, Georgiades, Ginty, Girdler, Heaney, Heim, Kapuku, Koo-Loeb, Launer, Lovallo, Lovallo, Lupien, Lynch, Markovitz, Matthews, Matthews, McClelland, Murdison, Newman, Novak, Painter, Panknin, Phillips, Phillips, Phillips, Pintrich, Pruessner, Rabbitt, Ravelli, Robbins, Rottenberg, Roy, Salomon, Singh-Manoux, Sloan, Waldstein, Waldstein, Waldstein, Wolf, Wood, Wright, York   +67 more
core   +1 more source

Prescription drug monitoring programs use mandates and prescription stimulant and depressant quantities

BMC Public Health, 2023
Background While the mandate to check patients’ prescription history in Prescription Drug Monitoring Program (PDMP) database before prescribing/dispensing controlled drugs has been shown to be an important tool to curb opioid abuse, less is known about ...
Christian Gunadi, Yuyan Shi
doaj   +1 more source

Neferine alleviates chronic stress-induced depression by regulating monoamine neurotransmitter secretion and gut microbiota structure

Frontiers in Pharmacology, 2022
Neferine (Nef) might possess anti-depressive properties; however, its therapeutic effects are yet to be elucidated. Therefore, in this study, we aimed to explore the anti-depressant property of Nef using a mouse model of chronic stress-induced depression.
Zaiquan Dong, Zaiquan Dong, Qinglian Xie, Feiyu Xu, Xiaoling Shen, Yanni Hao, Jin Li, Haizhen Xu, Qiang Peng, Weihong Kuang, Weihong Kuang   +10 more
doaj   +1 more source

Depression [PDF]

Annals of Epidemiology, 2009
This is an invited article on how my career as an epidemiologist studying depression unfolded. The role of the Civil Rights movement in opening the PhD doors to women at Yale began my career. The unfolding of depression studies are described. These studies included a clinical trial of medication and what later was known as interpersonal psychotherapy ...
openaire   +2 more sources

Responses of substantia gelatinosa neurons to putative neurotransmitters in an in vitro preparation of the adult rat spinal cord [PDF]

, 1983
Extracellular recordings were performed from neurons of the substantia gelatinosa (SG) in an in vitro preparation obtained from the spinal cord of adult rats. About 40% of neurons were spontaneously active.
B. Sutor, Bennett, Cervero, Cervero, Cervero, Cervero, Coggeshall, Coggeshall, Dhanjal, Dhanjal, Dubuisson, Fry, Hentall, Hunt, Hökfelt, Kumazawa, Kumazawa, Light, Miletic, Murase, Price, Ruda, Sumal, W. Zieglgänsberger, Wall, Wall, Williams, Yoshimura, Zieglgänsberger, Zieglgänsberger   +29 more
core   +1 more source